3 citations
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February 2019 in “Der Urologe” This review discusses the risk of central nervous side effects, such as dementia and depression, from drugs used to treat lower urinary symptoms related to benign prostatic hyperplasia, and highlights inconsistent evidence across different medications.
1 citations
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September 2024 in “Journal of Oncology Pharmacy Practice” In this report, a 77-year-old woman treated for essential thrombocytosis with low-dose hydroxyurea experienced an unexpected change in hair color from gray to dark brown after 20 weeks, highlighting a potential aesthetic side effect of the drug, in addition to therapeutic effects.
1 citations
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October 2023 in “The Journal of nutrition, health & aging” In this study, hair levels of zinc and chromium were associated with a reduced likelihood of age-related cognitive decline in centenarians and oldest-old adults, suggesting further research is needed on these elements' potential role in cognitive health among the elderly.
July 2025 in “Journal of Advanced Nursing” This study observed that first-time mothers reported a gradual decrease in postpartum symptoms from an average of 7 at one month to 5.3 at three months, with pervasive issues like lack of energy and irritability, especially among older mothers.
December 2023 in “Frontiers in oncology” The study found that patients over 70 with advanced ovarian cancer may have better overall and progression-free survival with weekly paclitaxel-carboplatin chemotherapy compared to a three-weekly regimen, despite increased blood-related toxicities.
November 2022 in “Innovation in aging” This study reports that hair cortisol measurement in older Puerto Rican adults found a significant portion had non-detectable cortisol levels, especially among black participants, influencing exclusion rates in such populations.
April 2017 in “European Psychiatry” This case report describes a 64-year-old woman who developed delusions after starting citalopram, highlighting citalopram-induced psychosis in older adults as a potential but rare side effect.
March 2016 in “The Journal of Urology” This historical review traces the discovery of 5-alpha reductase inhibitors, widely used in urology, from the study of guevedoces, Dominican children with a rare disorder leading to significant androgenization at puberty.
September 2022 in “Journal of The American Academy of Dermatology” This study examined the incidence of hyperkalemia in women over 65 with female pattern hair loss and spironolactone use, but the findings on risk remain unclear.
417 citations
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February 2004 in “The Journal of Clinical Endocrinology and Metabolism” This study found that testosterone therapy increased bone mineral density in older men with low testosterone, and combining it with finasteride may reduce prostate enlargement associated with testosterone treatment.
57 citations
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August 2020 in “Journal of the American Geriatrics Society” This study found that nearly 80% of Finnish adults aged 70 to 93 had at least one skin disease requiring treatment, with men more affected than women.
26 citations
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March 2001 in “PubMed” This article reviews the effect of aging on male hormone levels and fertility, highlighting the need for more research on the benefits and risks of androgen supplementation in older men.
10 citations
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April 2022 in “BMJ Open” This study found that lower urinary tract symptoms were linked to reduced functional ability in older adults, with distinct associations for nocturia in men and frequency, urgency, and overactive bladder in women.
5 citations
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April 2023 in “Journal of Multidisciplinary Healthcare” This study found that chemical elements, particularly hair selenium, may indicate nutritional status in older adults, with variations observed by age and gender.
2 citations
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January 2025 in “Advances in Skin & Wound Care” This study from ISTAP emphasizes the importance of preventing skin tears, particularly in vulnerable populations like older adults and neonates, and recommends strategies such as using silicone-based adhesives, emollient therapy, and maintaining a safe environment to reduce the risk of these injuries.
1 citations
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January 2025 in “Reproductive Biology and Endocrinology” This study suggests that supplementing with a cell-free fat extract might enhance embryo development and improve clinical outcomes in older women experiencing in vitro fertilization failure.
1 citations
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April 2020 in “Journal of The American Academy of Dermatology” This article discusses the approval status of 5α-reductase inhibitors for androgenetic alopecia, noting finasteride is FDA-approved for certain men while dutasteride is not approved in the US for this condition; it reports no new results.
1 citations
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October 2015 in “Actas Dermo-Sifiliográficas” June 2026 in “Comprehensive Psychoneuroendocrinology” In this study, researchers observed a curvilinear relationship between loneliness and hair cortisol concentration among older adults at elevated cardiovascular risk, with cortisol levels higher at low-to-moderate loneliness and lower at higher loneliness, though results were sensitive to some data exclusions.
March 2026 in “The Journal of Sexual Medicine” In this study, older women aged 70 and above, treated for sexual dysfunction using carefully monitored hormone therapy, reported improvements in sexual function and symptom relief, with no incidences of cancer or thromboembolic events, though some experienced breast tenderness and hair changes.
January 2026 in “Psychoneuroendocrinology” In this study, researchers observed that loneliness was positively linked to higher hair cortisol levels among African American men but not women, suggesting a potential sex-specific association between loneliness and stress-related physiological pathways.
October 2025 in “Journal of the Endocrine Society” In this case report, an 80-year-old woman experienced elevated alkaline phosphatase levels due to the use of Viviscal hair supplements. Her levels returned to normal after discontinuing the supplement, highlighting the need for clinicians to consider supplements as potential causes of abnormal lab results.
February 2025 in “Journal of Women & Aging” This study identified a significant trend among Black women towards less frequent use of complex hairstyles and salon visits over 30 years, while managing grey hair became a key element of personal and social identity.
December 2023 in “Y Dược học” In this study, researchers found that 11.5% of older outpatients in Vietnam experienced post-COVID-19 hair loss; women, those single or divorced, and individuals with prior COVID-19 hospitalizations were more likely to report hair loss.
October 2014 in “Aktuelle Dermatologie” This study reports that elderly men with baldness and comorbid conditions experienced persistent scalp erosions following topical treatment with imiquimod or diclofenac, suggesting alternative therapies should be considered for this group.
August 2014 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study reported that administering a supraphysiological dose of testosterone for one year resulted in minor cognitive benefits and decreased depressive symptoms in older hypogonadal men, but major cognitive improvements were not observed.
December 2010 in “Journal of the American Geriatrics Society” This article highlights the complexity of diagnosing hyponatremia in older adults, emphasizing the need to evaluate urinary tract obstruction, medication effects, and age-related changes rather than relying solely on spot urinary values.
January 2001 in “亚洲男性学杂志:英文版” This review discusses hormonal changes in aging men and suggests the need for more research on androgen supplementation and partial androgen deficiency, without presenting new clinical findings.
October 2022 in “British Journal of Dermatology” In this retrospective study, the incidence of hyperkalaemia within the first year of spironolactone use was assessed among women over 65 with female-pattern hair loss, highlighting a potential safety concern.
506 citations
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March 2005 in “The Journal of Clinical Endocrinology and Metabolism” This study found that testosterone therapy improved physical performance and strength in older men with low testosterone over 36 months, whether administered alone or with finasteride.