147 citations
,
November 2020 in “Journal of Internal Medicine” This review discusses factors contributing to COVID-19 severity disparities, highlighting age, comorbidities, race/ethnicity, and gender, and reports no new clinical findings; it emphasizes understanding these mechanisms to address risk differences.
140 citations
,
January 2021 in “Journal of the International Society of Sports Nutrition” This source reports that while creatine supplementation is popular for improving muscle mass and performance, questions about its efficacy and safety persist. An expert team is reviewing literature to address concerns like water retention, renal effects, and its benefits across different populations and uses.
113 citations
,
July 2020 in “Communications biology” This review suggests that understanding the biological and molecular reasons for more severe COVID-19 in men, particularly those at risk for prostate cancer, could improve management of these patients, but reports no new results.
84 citations
,
August 2023 in “Drugs” This article describes the development milestones and recent approvals of ritlecitinib for treating severe alopecia areata, with approvals in the USA and Japan and ongoing regulatory reviews in other regions.
80 citations
,
January 1979 in “Journal of Surgical Oncology” This paper reviews keratoacanthoma as a tumor that resembles but rarely progresses to squamous cell carcinoma, detailing its stages, potential origins, and distinguishing features from other similar growths, without reporting new clinical results.
77 citations
,
April 1999 in “Dermatologic Clinics” This article reviews how new observations have revolutionized surgical hair restoration and highlights the logical applications and prior illogical judgments that delayed this advancement, without reporting new results.
62 citations
,
April 2013 in “Steroids” This review discusses the age-related diagnostic challenges and comorbidities of polycystic ovarian syndrome and provides no new clinical findings; the authors emphasize the role of obesity in insulin resistance among affected women.
38 citations
,
February 2012 in “Aesthetic Surgery Journal” This article discusses the importance of individualized treatment plans based on the morphological characteristics of the aging face in surgical rejuvenation, but it provides no new findings.
35 citations
,
August 2004 in “Epilepsy & behavior” In this study, divalproex sodium extended-release was found to be more tolerable and preferred by patients compared to the delayed-release formulation, with improved seizure control and psychiatric symptom relief.
35 citations
,
February 2004 in “Veterinary Dermatology” This study observed that cutaneous lymphocytosis in cats is a slowly progressive and relatively benign disease, but predicting individual clinical outcomes from skin lesions was not possible.
35 citations
,
January 1996 in “Dermatologic clinics” This article reviews tinea capitis as a common infectious scalp condition in children, reporting no new findings.
34 citations
,
July 2013 in “Clinical Cosmetic and Investigational Dermatology” This study observed that while topical drug therapy for erosive pustular dermatosis rarely leads to complete resolution, surgery may achieve remission in male patients.
32 citations
,
September 1997 in “Dermatologic Surgery” This study found that mini-micrografting and plug methods achieve comparable hair density, but mini-micrografting requires fewer sessions due to its dense graft packing.
30 citations
,
September 2016 in “BMJ” This study found that 5-α reductase inhibitors do not significantly increase the risk of erectile dysfunction in men with benign prostatic hyperplasia or alopecia, although duration of benign prostatic hyperplasia may elevate risk.
30 citations
,
June 2013 in “Optometry and vision science” This study reports that a clinical sequence can help eye care practitioners identify Demodex mites, which are often underdiagnosed and undertreated in ocular surface diseases.
27 citations
,
October 2020 in “Drugs” This article reviews the development milestones of clascoterone up to its first approval for treating acne vulgaris, reporting no new clinical results for androgenetic alopecia.
27 citations
,
August 2008 in “Mayo Clinic proceedings” This review discusses the diagnosis, management, and treatment options for peripheral arterial disease and does not report new clinical findings; the authors emphasize the need for early diagnosis and comprehensive management.
26 citations
,
December 1979 in “Journal of Cutaneous Pathology” This study found that trichostasis spinulosa was present in some seborrheic keratoses, indicating they may partly originate from hair follicle cells.
25 citations
,
May 2004 in “Prenatal Diagnosis” This study suggests that prenatal genetic diagnosis of MELAS syndrome using amniotic cells may not reliably predict fetal outcomes due to phenotypic diversity observed in siblings with similar levels of mutant mtDNA.
22 citations
,
October 2000 in “British Journal of Haematology” This article discusses the development of non-myeloablative stem cell transplants, which may expand the safe treatment range of allogeneic SCT, but presents no new clinical results.
21 citations
,
October 2011 in “PloS one” In this study, researchers identified three molecules in hair that varied with age, suggesting potential markers for aging and targets for cosmetic products.
20 citations
,
November 2004 in “Archives of Pathology & Laboratory Medicine” This case report describes a rare instance of melanocytic matricoma, a benign pigmented papule found in sun-damaged skin of an elderly individual, highlighting its distinct clinical and pathological features.
17 citations
,
September 2003 in “Journal of Investigative Dermatology Symposium Proceedings” This study found that anthralin and mechlorethamine were the most effective therapies among those tested in AA-affected rodent models, providing a basis for further analysis of their mechanisms in Alopecia Areata.
16 citations
,
January 2007 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas” This review discusses frontal fibrosing alopecia and reports no clinical results; the authors note that no therapeutic options tested, including corticosteroids, finasteride, and minoxidil, have shown clear benefits.
15 citations
,
August 2017 in “Pediatrics in review” This review covers hypertension in children and adolescents, detailing the importance of proper diagnosis, screening, and pharmacologic treatment while highlighting the need for further research on screening benefits.
15 citations
,
November 2008 in “Facial Plastic Surgery” This review discusses the common issues with unnatural appearing hair transplants and presents potential treatment approaches, but does not provide new clinical results.
15 citations
,
May 2005 in “Seminars in Plastic Surgery” This article details techniques for eyebrow and eyelash reconstruction surgery with hair follicular unit transplantation but reports no new clinical results; the author describes the advantages over other methods.
15 citations
,
May 2004 in “Facial Plastic Surgery Clinics of North America” This article describes a technique for improving the aesthetic results of surgical hair restoration by recycling plug grafts into smaller grafts, which can be combined with other procedures like scalp lifting and reductions.
14 citations
,
November 2023 in “Mycoses” In this study, Kerion Celsi, a deep fungal scalp infection, is highlighted as being rare in neonates but more common in children over 3 years, requiring medical treatment with antifungals and antibiotics to prevent scarring alopecia and distinguish it from bacterial infections.
14 citations
,
January 2008 in “Dermatology Online Journal” This review discusses the use of anti-hormonal therapies for female androgenetic alopecia and notes that while some treatments show promise, larger controlled studies are needed to define their roles and effectiveness.