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The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

Hair diversity is influenced by complex genetics and environmental factors, requiring more research for practical solutions.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Minoxidil works in liver and outer hair root sheath for hair growth.

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.

Women with early hair loss have higher blood pressure and aldosterone; screening and treatment may help.

Gonadal dysgenesis, like Turner's and Klinefelter's syndromes, negatively affects bone health, but hormone treatments can help.

The effects of estrogen on human hair growth are unclear and need more research.

Antiandrogen therapy helped increase hair growth in women with hormonal imbalances related to baldness.

The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.

Quercetin may help with PCOS symptoms, but more research is needed.

Dutasteride-containing mesotherapy effectively treats female hair loss, improving density and thickness with minimal side effects.

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

Hormones during pregnancy and lactation keep skin stem cells inactive, preventing hair growth.

Finger length ratios are not linked to the number of specific gene repeats affecting testosterone sensitivity.

The French Endocrine Society suggests diagnosing PCOS with two of three signs, recommends lifestyle changes and clomiphene for treatment, and calls for more research on certain treatments and tests.

Treat hair loss with finasteride, minoxidil, or surgery; consider side effects and severity.

Testosterone replacement therapy can prevent men from fathering children and should not be used by those wanting to stay fertile.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

Adrenal disorders can cause lasting brain and behavior issues in children.

Skin problems like acne, dry skin, and nail and hair changes are common in patients taking EGFR inhibitors.

AR/EDA2R gene linked to early-onset female hair loss, but 20p11 gene not involved.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Hirsutism is excessive male-pattern hair growth in women, often caused by hormonal imbalances, and requires ongoing treatment to manage.

A male with aromatase deficiency improved bone health with estradiol treatment.

New treatments for a chronic skin condition show promise, but individualized plans are crucial due to varying responses.

More pediatric-specific research and guidelines are needed to improve hidradenitis suppurativa treatment in children and adolescents.