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New CRISPR/Cas9 variants and nanotechnology-based delivery methods are improving cancer treatment, but choosing the best variant and overcoming certain limitations remain challenges.

Different genes cause Female Pattern Hair Loss compared to male hair loss, and treatments vary, but more research is needed to understand it fully.

Sex hormones affect brain injury differently in males and females.

The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.

Hair loss in women may have multiple causes, and eyebrow regrowth possible with specific injections.

Hormonal treatments are effective as a second-line option for moderate-to-severe acne in females, but should be used with caution due to health risks.

Mesotherapy might help reduce fat in specific areas for those close to their ideal weight, but more research and care are needed to ensure safety.

Estrogen and prolactin may play bigger roles in female hair loss than previously thought.

AGA in children needs careful diagnosis due to low androgen levels and possible other causes.

The length of CAG repeats in the androgen receptor gene is linked to ovarian reserve but does not affect how the ovaries respond to stimulation.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

The document concludes that managing PCOS involves treating symptoms and reducing long-term metabolic risks, with lifestyle changes being important.

Estrogens and progesterone are key in regulating melasma pigmentation.

Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.

TNFα, IFNγ, and Substance P significantly affect prolactin levels in human skin, suggesting new treatments for skin and hair conditions.

Different anti-androgen medications can help treat excessive hair growth, but the right choice depends on accurate diagnosis.

Understanding how DHT works is important for diagnosing and treating hormone-related disorders.

Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.

Spironolactone is safe for treating female hair loss, but the safety of other drugs is uncertain.

Testosterone affects stress hormone levels differently in adolescent and adult male rats.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.

Alopecia patients have less GPER-1, which might affect hair loss.

The study suggests that a specific gene variation and higher gene activity are linked to increased baldness in Egyptian men.

5-alpha reductase inhibitors may reduce bladder cancer recurrence and improve survival.

The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.

Using neurohormones to control keratin can lead to new skin disease treatments.