Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

In this study, PEVIII, a nanocomposite chitosan-coated vesicle containing both α-hederin and hederacoside C, demonstrated notable antibacterial activity against Pseudomonas aeruginosa in a keratitis model, showing significant lesion reduction, tissue improvement, and decreased bacterial load and inflammatory markers compared to other treatments.

This study presents cases of paraproteinemic keratopathy associated with multiple myeloma and MGUS, highlighting varied treatment responses and the need for long-term follow-up to better understand disease progression and management.

This study reported that distinct stem/progenitor populations in the ocular surface epithelium have different cell division frequencies and respond differently to injury, with specific spatial compartmentalization and migration behaviors.

This case report on a 17-year-old with Vogt-Koyanagi-Harada syndrome found that while steroid treatments improved vision during uveitis episodes, recurring ocular issues led to significant long-term visual impairment.

This study observed retinal and optic nerve damage in patients who had taken finasteride, suggesting potential ocular toxicity associated with the drug's use.

This study found that the ocular surface epithelium in mice contains distinct stem cell populations with unique cell division dynamics that change behaviorally in response to different levels of injury.

This retrospective study in pediatric patients with Sjögren's syndrome found consistent indications of tear film instability and identified systemic features like arthralgia, Raynaud's phenomenon, and frequent autoantibody positivity, underscoring the value of integrating clinical and ophthalmological assessments for early diagnosis.

This review found promising benefits of platelet-rich plasma for treating ocular surface diseases in animals, but methodological flaws currently preclude recommending it as standard care.

This review concluded that near-infrared and red light photobiomodulation shows potential for certain ocular conditions like age-related macular degeneration and dry eye disease, but clinical evidence is still mixed and insufficient to establish it as a standard therapy.

This study found no significant differences in dry eye disease parameters between female patients with androgenetic alopecia and healthy controls, although meibum quality was better in the alopecia group, suggesting complex hormonal interplay affecting ocular health.

This study reports that a new transplantation technique using tissue-engineered stem cells successfully reconstructed corneal epithelium in an animal model of severe ocular surface disease.

This study found that switching patients with glaucoma or ocular hypertension from benzalkonium chloride-latanoprost to preservative-free latanoprost maintained intraocular pressure control and improved tolerability, potentially enhancing treatment adherence and quality of life.

In this study, researchers developed an in-situ gel formulation of antibacterial Levofloxacin for the eye, which showed prolonged drug release, increased residence time, and effective antibacterial action, suggesting it may be a safe and effective ocular delivery system for antibiotics.

This study evaluated 386 patients with inborn errors of immunity and found that over half exhibited cutaneous, ocular, or hair manifestations, with bacterial skin infections and eczema being particularly prevalent. These findings may aid early diagnosis, especially in pediatric cases.

This review discusses Limbal Mesenchymal Stem Cell Secretome therapy for ocular chemical injuries, noting its potential in reducing inflammation and corneal opacity, but reports no new clinical results.

This article argues that human scalp hair follicles could serve as a surrogate model for studying immune privilege in the human eye, offering a novel approach for ocular IP research.

This study found that stressed dermal fibroblasts significantly increased dopa oxidase activity in melanocytes from hair, skin, and eyes, suggesting the involvement of fibroblast-derived factors like basic Fibroblast Growth Factor.

This study observed that a dual-loaded niosomal in situ gel delivered effective antimicrobial and antioxidant properties for potential ophthalmic applications, showing superior inhibition of methicillin-resistant Staphylococcus aureus adhesion.

This article reviews the current literature on rosacea, focusing on the new subtype classification system and the main theories of its pathogenesis, but reports no new clinical results.

This review discusses the shift in toxicity profiles of cancer therapies from traditional chemotherapy to targeted agents, noting similar overall toxicities but with different side effects, and reports no new findings.

This study found that female COVID-19 survivors were more likely than males to experience multiple long-term post-COVID symptoms, including fatigue, pain, hair loss, and mood disorders.

In this study, researchers examined two new cases of trichothiodystrophy and observed that the condition is linked to decreased synthesis of high-sulfur matrix proteins in hair.

This study found that Demodex folliculorum and Demodex brevis mites can cause eyelid follicular and glandular changes, potentially contributing to ocular disease in humans.

This study found that stem cells from mouse hair follicles successfully reconstructed the ocular surface in most limbal stem cell deficiency mice, demonstrating potential for treating the condition in a mouse model.

This review discusses the range of long-term complications, including mucocutaneous, ocular, and psychological sequelae, for survivors of Stevens–Johnson syndrome and toxic epidermal necrolysis, but reports no new clinical results.

This article reports a case where the IOP-lowering drug bimatoprost was associated with eyelash hypertrichosis.

This review highlights essential preoperative assessments for ophthalmologists and non-oculo-facial surgeons performing upper facial rejuvenation, emphasizing the importance of understanding ocular and periocular anatomy to achieve both cosmetic and functional improvements.

This case report identified lash ptosis as a potential complication of latanoprost therapy in a 61-year-old man with ocular hypertension.

This study reports that a clinical sequence can help eye care practitioners identify Demodex mites, which are often underdiagnosed and undertreated in ocular surface diseases.

This review discusses the cutaneous application of bimatoprost ophthalmic solution 0.03% for enhancing upper eyelash growth and suggests it is both safe and effective; no new clinical results are reported.