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Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Some medicinal plants can help heal wounds and may lead to new treatments.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Women with PCOS face higher risks of diabetes and heart disease, and these risks increase with obesity.

Dermatoscopy and videodermatoscopy are useful for diagnosing and monitoring various skin, hair, and nail conditions.

Too much androgen can cause hair loss; finasteride may help.

Periodontal ligament stem cells show promise for regrowing tissues but require more research for safe, effective use.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Hair elemental analysis could be useful for health and exposure assessment but requires more standardization and research.

Treatments for permanent hair loss from scarring aim to stop further loss, not regrow hair, and vary by condition, with partial success common.

New hormonal contraceptives are safer, have fewer side effects, and offer health benefits for women.

Skin problems in COVID-19 patients are rare and may be due to the body's complex immune response or blood clotting issues.

Despite progress, better treatments and understanding are needed for the high rates of long-term issues and deaths linked to eating disorders.

Fat tissue cells are a promising option for healing various diseases, but more research is needed to ensure they are safe and effective.

Androgens play a role in female sexual function, and testosterone therapy can help women with low sexual desire, but more research is needed on treatments and long-term safety.

Some heart drugs show promise for other conditions, but more research is needed to confirm their effectiveness and safety.

European guidelines recommend regular eye and ear exams, skin care, vitamin D supplements, and cautious use of medications for managing congenital ichthyoses.

Finasteride effectively treats male pattern baldness, improving hair growth and density.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Dupilumab is being tested for many new skin, respiratory, and gastrointestinal conditions.

Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

Testosterone therapy can help improve sexual desire and function in postmenopausal women but may cause side effects and is not FDA-approved for this use.

Adult female acne requires a comprehensive treatment approach, including medical options and lifestyle changes, with attention to psychological well-being.