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research Table of Contents
![Diseases of the Hair and Scalp in the Elderly](/images/research/3edb9f63-feb8-4127-b306-cf38a9fc1d35/small/15561.jpg)
research Diseases of the Hair and Scalp in the Elderly
Aging can lead to poorer scalp and hair health, including less hair and more scalp diseases, which should be managed to help older people feel better.
![Cutaneous Mycoses in the Elderly](/images/research/9d8d9822-aee2-4713-9a1a-c02581884a24/small/15563.jpg)
research Cutaneous Mycoses in the Elderly
Skin fungal infections are more common in older adults due to factors like obesity, poor circulation, reduced mobility, and weakened immune defenses from certain medications.
![Sex Differences in COVID-19: The Role of Androgens in Disease Severity and Progression](/images/research/dec5d405-a880-4ffa-93c2-fa19700a400c/small/13332.jpg)
research Sex Differences in COVID-19: The Role of Androgens in Disease Severity and Progression
Male hormones like testosterone may make COVID-19 worse, and testing for sensitivity to these hormones could help predict how severe a patient's symptoms might be. Treatments that reduce these hormones are being explored.
![Kisspeptin and LH Pulsatile Temporal Coupling in PCOS Patients](/images/research/27af8e45-cd6b-4b52-ac49-3c487edd5e45/small/13629.jpg)
research Kisspeptin and LH Pulsatile Temporal Coupling in PCOS Patients
Women with regular menstrual cycles and PCOS have linked kisspeptin and LH hormone patterns, unlike those with irregular cycles.
![The Role of Pannexin 3 in Bone Biology](/images/research/f88e572a-c30c-4236-a1e8-0b6274596b2b/small/26299.jpg)
research The Role of Pannexin 3 in Bone Biology
Pannexin 3 is important for bone formation and the development of bone cells.
![Characterization and Chromosomal Localization of Human Hair-Specific Keratin Genes and Comparative Expression During the Hair Growth Cycle](/images/research/41c7206a-64af-41c7-97d4-cf0b1ec3a312/small/29681.jpg)
research Characterization and Chromosomal Localization of Human Hair-Specific Keratin Genes and Comparative Expression During the Hair Growth Cycle
Two specific hair keratin genes are active during hair growth and decline as hair transitions to rest.
![Gene Expression of Type 2 17β Hydroxysteroid Dehydrogenase in Scalp Hairs of Hirsute Women](/images/research/fe399dd0-cd41-4109-b3b0-69032311536e/small/32635.jpg)
research Gene Expression of Type 2 17β Hydroxysteroid Dehydrogenase in Scalp Hairs of Hirsute Women
Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.
![Tumor Necrosis Factor-Alpha and Polycystic Ovarian Syndrome: A Clinical, Biochemical, and Molecular Genetic Study](/images/research/7c04dea7-ab8e-482b-8704-8cbe4163007e/small/14379.jpg)
research Tumor Necrosis Factor-Alpha and Polycystic Ovarian Syndrome: A Clinical, Biochemical, and Molecular Genetic Study
High levels of TNF-α may contribute to obesity and insulin resistance in PCOS, but not due to the C850T genetic variation.
![Skin Manifestations of Chronic Kidney Disease](/images/research/9d366684-9f80-454d-9f5a-3fe4e6a07846/small/24308.jpg)
research Skin Manifestations of Chronic Kidney Disease
Chronic kidney disease can cause skin problems that affect patient quality of life, and treating these conditions can improve outcomes.
![Prevalence of Vitamin D Deficiency in Slovak Women with Polycystic Ovary Syndrome and Its Relation to Metabolic and Reproductive Abnormalities](/images/research/a2f25ee0-2988-4ca0-9f8a-eb2fd0fb8ac3/small/14280.jpg)
research Prevalence of Vitamin D Deficiency in Slovak Women with Polycystic Ovary Syndrome and Its Relation to Metabolic and Reproductive Abnormalities
Vitamin D deficiency is common in women with PCOS and linked to some metabolic problems, but not the main cause of their metabolic issues.
![The Use of Complementary and Alternative Medicine Among Dermatology Outpatients in Eastern Turkey](/images/research/baee3018-c419-48f8-9542-30ee520c9b9a/small/24477.jpg)
research The Use of Complementary and Alternative Medicine Among Dermatology Outpatients in Eastern Turkey
Almost half of the dermatology patients in Eastern Turkey use alternative medicine, which can be risky and delay proper treatment.
![Long-Term Response of Hirsutism and Other Hyperandrogenic Symptoms to Combination Therapy in Polycystic Ovary Syndrome](/images/research/23277e4d-48e4-419a-b7b5-127102e297ea/small/13625.jpg)
research Long-Term Response of Hirsutism and Other Hyperandrogenic Symptoms to Combination Therapy in Polycystic Ovary Syndrome
Combination therapy with oral contraceptives and spironolactone improves hair growth, menstrual issues, and acne in women with PCOS.
![Capitalizing on Aging Anxieties: Promissory Discourse and the Creation of an Anti-Aging Treatment Market](/images/research/acbeaddd-0d36-4e1c-9597-d975299192b1/small/21588.jpg)
research Capitalizing on Aging Anxieties: Promissory Discourse and the Creation of an Anti-Aging Treatment Market
The anti-ageing treatment market is growing by exploiting fears of ageing with unproven promises, which could harm public trust and genuine science.
![DNA Phenotyping: Current Application in Forensic Science](/images/research/6cd1822a-c057-4fe4-b3f8-459b22664123/small/13479.jpg)
research DNA Phenotyping: Current Application in Forensic Science
DNA phenotyping helps predict physical traits from DNA with varying accuracy and requires careful ethical and legal handling.
![Expression of an Olfactomedin-Related Gene in Rat Hair Follicular Papilla Cells](/images/research/061a2e44-5c15-4691-9a60-b753b8e97e5b/small/29515.jpg)
research Expression of an Olfactomedin-Related Gene in Rat Hair Follicular Papilla Cells
FP-1 is a key protein in rat hair growth, active only during the growth phase.
![Whole Exome Sequencing in Alopecia Areata Identifies Rare Variants in KRT82](/images/research/7fc8bfe0-a1a3-450b-8eb0-bd17b1387bcd/small/30582.jpg)
research Whole Exome Sequencing in Alopecia Areata Identifies Rare Variants in KRT82
Rare changes in the KRT82 gene are linked to a higher risk of Alopecia Areata.
![Polymeric Micelle Mediated Follicular Delivery of Spironolactone: Targeting the Mineralocorticoid Receptor to Prevent Glucocorticoid-Induced Activation and Delayed Cutaneous Wound Healing](/images/research/f8bae941-45a2-4684-8aff-176148925211/small/20790.jpg)
research Polymeric Micelle Mediated Follicular Delivery of Spironolactone: Targeting the Mineralocorticoid Receptor to Prevent Glucocorticoid-Induced Activation and Delayed Cutaneous Wound Healing
Using polymeric micelles to deliver spironolactone topically could improve wound healing in skin affected by glucocorticoids.
![Androgenetic Alopecia May Be Associated With Weaker COVID-19 T-Cell Immune Response: An Insight Into a Potential COVID-19 Vaccine Booster](/images/research/8467622f-f658-451f-8369-264b49afce83/small/5071.jpg)
research Androgenetic Alopecia May Be Associated With Weaker COVID-19 T-Cell Immune Response: An Insight Into a Potential COVID-19 Vaccine Booster
Hair loss may link to weaker COVID-19 immunity, suggesting possible need for extra vaccine boost.
![Use of H-1 Antihistamine in Dermatology: More Than Itch and Urticaria Control: A Systematic Review](/images/research/1d8d840a-6993-4327-8065-41d584adb532/small/17235.jpg)
research Use of H-1 Antihistamine in Dermatology: More Than Itch and Urticaria Control: A Systematic Review
H-1 antihistamines may help with various skin conditions, but more research is needed to confirm their effectiveness.
![Early Dengue Virus Infection in Human Skin: A Cycle of Inflammation and Infectivity](/images/research/d3967e0e-ec0b-4914-b0ea-6cc20c9c4d4d/small/14180.jpg)
research Early Dengue Virus Infection in Human Skin: A Cycle of Inflammation and Infectivity
Chicken feather gene mutation helps understand human hair disorders.
![Influence of the Alkylsulfonylamino Substituent Located at the 6-Position of 2,2-Dimethylchromans Structurally Related to Cromakalim: From Potassium Channel Openers to Calcium Entry Blockers?](/images/research/030af8b9-199e-4ace-8edd-cbb135cda36b/small/14305.jpg)
research Influence of the Alkylsulfonylamino Substituent Located at the 6-Position of 2,2-Dimethylchromans Structurally Related to Cromakalim: From Potassium Channel Openers to Calcium Entry Blockers?
New compounds similar to cromakalim were less effective at inhibiting insulin release but improved in solubility and one acted as a calcium entry blocker, not a potassium channel opener.
![Synthesis and Bioactivity of New Finasteride Conjugate](/images/research/085e36e9-cf48-4b43-9864-2b87da3971a7/small/3057.jpg)
research Synthesis and Bioactivity of New Finasteride Conjugate
New Finasteride conjugate improves prostate treatment and vital signs in rats.
![A Novel Technique for Repositioning Lower Eyelid Fat via the Transoral Approach in Association with Midface Lift](/images/research/40b00c43-cb3f-4334-8ea2-5685ea869241/small/39509.jpg)
research A Novel Technique for Repositioning Lower Eyelid Fat via the Transoral Approach in Association with Midface Lift
The new technique for repositioning lower eyelid fat with a midface lift is easier, faster, and has better results with fewer complications.
![Polycystic Ovarian Syndrome (PCOS) Awareness Among Female Students at Qassim University, Qassim Region, Saudi Arabia](/images/research/7b037e49-f1ae-4812-a465-cb8b43ad3bc1/small/30199.jpg)
research Polycystic Ovarian Syndrome (PCOS) Awareness Among Female Students at Qassim University, Qassim Region, Saudi Arabia
Most female students at Qassim University know about PCOS, but there are still misunderstandings about it.
![Implantation of Biocompatible Fibers for the Temporary Correction of Scalp Scars and Androgenetic Alopecia](/images/research/1e7a5e6e-25f3-4eff-a0e8-5c4cb8974951/small/2483.jpg)
research Implantation of Biocompatible Fibers for the Temporary Correction of Scalp Scars and Androgenetic Alopecia
Fiber implants effectively treat permanent hair loss with over 85% success and minimal complications.
![Transgenic HPV11-E2 Protein Modulates URR Activity In Vivo](/images/research/cf011911-4de3-44e8-9b9c-b53932c9cb99/small/39540.jpg)
research Transgenic HPV11-E2 Protein Modulates URR Activity In Vivo
The E2 protein affects gene activity in hair follicles of mice.
![Alopecia Universalis After Sitagliptin Intake](/images/research/17ec3778-dbe7-47a5-9df4-9a1dac7ece16/small/30160.jpg)
research Alopecia Universalis After Sitagliptin Intake
A patient's hair loss may be linked to their diabetes medication, Sitagliptin.
![A Small Scale Study to Evaluate the Efficacy of Microneedling With or Without Platelet-Rich Plasma in the Treatment of Post-Clipping Alopecia in Dogs](/images/research/f10fe27e-e428-4d4f-b3b2-76ef40375269/small/4849.jpg)
research A Small Scale Study to Evaluate the Efficacy of Microneedling With or Without Platelet-Rich Plasma in the Treatment of Post-Clipping Alopecia in Dogs
Microneedling with platelet-rich plasma helps dog hair regrow faster than microneedling alone.