research Cutaneous Reactions to Drugs
Skin reactions are a common reason for emergency visits due to drug allergies, with some severe cases needing intensive care.
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research Non-Clinical Safety Evaluation and Risk Assessment of Aleglitazar, a Dual PPAR α/γ Agonist, and Its Major Human Metabolite
Aleglitazar and its major metabolite are safe enough to proceed to Phase 3 clinical trials.
research Steroid Hormones: Overview and Medical Applications
Steroid hormones are crucial for body functions and have various medical uses, but their misuse can lead to dependence.
research Innovative Sequence of Docetaxel–Gemcitabine Based on Preclinical Data in the Treatment of Advanced Non-Small Cell Lung Cancer: A Phase I Study
The new chemotherapy combination for advanced lung cancer showed a 35.7% response rate but caused significant side effects.
research Investigational Medications in the Treatment of Alopecia
New treatments for hair loss are being developed using molecular biology.
research Leydig Cell Hyperplasia and Adenomas in Mice Treated with Finasteride, a 5α-Reductase Inhibitor: A Possible Mechanism
Finasteride causes abnormal growth in male mice cells at high doses.
research Treatment of Hidradenitis Suppurativa Evaluation Study: The THESEUS Prospective Cohort Study
Laser treatment and deroofing are effective options for hidradenitis suppurativa.
research Effect of Optimal Mixing Ratio of Dendropanax, Sea Salt, and Other Extracts on the Alleviation of Hair Loss Symptoms
The optimal mix of Dendropanax, sea salt, and other extracts can help reduce hair loss.
research Scalp Hair Sweating as a Predictor of Hair Cortisol Level in Humans Compared to Obesity and Other Confounders
Scalp hair sweating is a significant predictor of hair cortisol levels.
research Non-Invasive Human Skin Transcriptome Analysis Using mRNA in Skin Surface Lipids
The conclusion is that analyzing RNA from skin oils is a promising way to understand skin diseases.
research Androgenic Modulation of Arterial Baroreceptor Dysfunction and Neuroinflammation in Endotoxic Male Rats
Testosterone affects blood pressure control and inflammation in male rats with endotoxic shock, and blocking certain hormones may help treat it.
research Factors Influencing the Effect of Photobiomodulation in the Treatment of Androgenetic Alopecia: A Systematic Review and Analysis of Summary-Level Data
Higher energy, longer exposure, and pulse irradiation improve hair density in androgenetic alopecia treatment.
research Trichogenic Effect of Topical Ketoconazole Versus Minoxidil 2% in Female Pattern Hair Loss: A Clinical and Trichoscopic Evaluation
Minoxidil works faster, but ketoconazole is a safer alternative for female hair loss.
research Lipid Nanoparticles for Topical and Transdermal Delivery of Pharmaceuticals and Cosmeceuticals
Lipid nanoparticles improve drug delivery through the skin, offering stability, controlled release, and better compatibility with skin.
research Efficacy of Subcutaneous Injection of Platelet-Rich Plasma in Alopecia: A Clinical and Histological Pilot Study on a Rat Model with a Six-Month Long-Term Follow-Up Experience
Injecting platelet-rich plasma under the skin significantly improves hair growth and quality without harmful effects.
research Non-Invasive Method Distinguishes Chronic Telogen Effluvium From Mild Female Pattern Hair Loss: Clinicopathological Correlation
Washing test helps identify hair loss type, low iron levels significant.
research Skin Stem Cells: At The Frontier Between The Laboratory And Clinical Practice. Part 1: Epidermal Stem Cells
Epidermal stem cells show promise for future dermatology treatments due to ongoing advancements.
research Development of Uniform Protocol for Alopecia Areata Clinical Trials
A standard protocol for alopecia areata clinical trials was created to improve consistency and encourage more research.
research High-Resolution Mass Spectrometric Investigation of the Phase I and II Metabolites of Finasteride in Pig Plasma, Urine, and Bile
Finasteride metabolites found in pigs match human studies, making pigs a valid model for human drug research.
research Chemotherapy-Induced Alopecia
Chemotherapy often causes hair loss, which usually grows back within 3 to 6 months, but there's no effective treatment to prevent it.
research Mucosal TLR5 Activation Controls Healthspan and Longevity
Activating TLR5 in the gut can extend lifespan and improve health in aged mice.
research Engineered Exosomes and Composite Biomaterials for Tissue Regeneration
Exosomes show promise for future tissue regeneration.
research Assessing the Impact of Alopecia on Quality of Life, Depression, and Self-Esteem in Saudi Arabia
Alopecia significantly impacts mental health and quality of life, requiring psychological support.
research TLR2 Regulates Hair Follicle Cycle and Regeneration via BMP Signaling
TLR2 is important for hair growth and can be targeted to treat hair loss.
research Lineage Commitment of Dermal Fibroblast Progenitors Is Mediated by Chromatin De-repression
Skin cell types develop when specific genes are turned on by removing certain chemical tags from DNA.
research Efficient Editing of CSLD2 Orthologue by CRISPR/Cas9 Affects Cell Morphogenesis of Root Hair in Spinach
CRISPR/Cas9 editing in spinach affects root hair growth by altering specific genes.
research New Donor Excision Design for Better Hair Alignment in Hair Restoration Surgery
The new triangular flag-shaped design for incisions in hair transplant surgery provides better hair alignment and cosmetic appearance without extra scarring, especially for patients with specific hair directions.
research 3D Analysis of Facial Morphology in Dutch Children with Cancer
Children with cancer had slightly more unusual facial shapes than healthy kids, but not enough to easily tell them apart.
research Advances in the Chemical Structure of the Hair Surface, Surface Forces and Interactions
Understanding hair surface properties is key for effective hair care products.
research Molecular Basis of Maintaining Circannual Rhythm in the Skin of Cashmere Goat
Goat skin changes with the seasons due to genes affected by daylight and hormones.