46 citations
,
December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that Acvr1b signaling is crucial for both hair follicle development and cycling in mice, with the genetic disruption leading to hair loss and a thickened epidermis.
44 citations
,
September 2014 in “Cell Death & Differentiation” This review discusses the role of tumor suppressors in controlling tumor-associated inflammation and suggests that targeting this inflammation may counteract the effects of tumor suppressor loss.
43 citations
,
October 2008 in “Indian Journal of Plastic Surgery” This narrative review explores the historical use and significance of cosmetics in ancient India, detailing various formulations and botanical ingredients documented in Ayurvedic texts, but it reports no new research findings.
43 citations
,
September 2006 in “Annals of Plastic Surgery” This article presents a unique case of hair-thread tourniquet syndrome in a 3-month-old, with a hair causing bony erosion of the toe, and includes a literature review and meta-analysis.
42 citations
,
September 2018 in “Journal der Deutschen Dermatologischen Gesellschaft” This review discusses the distinct clinical and psychological aspects of adult female acne and reports no new clinical results, highlighting the need for a comprehensive management approach.
41 citations
,
April 2017 in “JAMA Dermatology” This study found that the top 10 film villains have a higher frequency of significant dermatologic features than the top 10 heroes, which may contribute to societal prejudice against individuals with skin conditions.
41 citations
,
March 1987 in “Journal of The American Academy of Dermatology” This study observed that 2% minoxidil solution was at least as effective as 3% for increasing hair growth and stabilizing bald areas in men with male pattern baldness.
40 citations
,
June 2023 in “Dermatology and Therapy” This study found that the emotional impact of alopecia areata is significant, but it may not correlate directly with the extent of hair loss since some individuals adapt to the condition.
39 citations
,
June 1982 in “The BMJ” Blood tests confirmed a baby in the womb had a CMV infection.
38 citations
,
January 2016 in “Cell Death and Disease” This review discusses the role of the TCL1 transgenic mouse model in understanding chronic lymphocytic leukemia biology and highlights the importance of exploring new pathogenetic and therapeutic targets.
38 citations
,
September 2014 in “Cell and Tissue Research” This review explores the infundibulum's role and importance in skin diseases and emphasizes the need for further research into its biology and potential therapeutic targeting, but it presents no new findings.
38 citations
,
May 2009 in “European journal of dermatology/EJD. European journal of dermatology” This study found that the TrichoScan method for evaluating hair loss showed excellent correlation with manual marking and provided more consistent, reproducible results with less variability and operator error.
38 citations
,
June 2005 in “Contact Dermatitis” This case report describes a patient with an allergic sensitization to minoxidil, indicating that such patients should pursue alternative therapies to treat androgenetic alopecia.
36 citations
,
April 1990 in “Dermatologic Clinics” This review discusses skin changes and dermatoses during pregnancy and reports no clinical findings, emphasizing a need for better understanding of their causes.
34 citations
,
September 2020 in “BMC Endocrine Disorders” This review highlights that while dexamethasone may reduce mortality in severe COVID-19, no other drugs have proven effectiveness for treatment, emphasizing the need for clinical trials of existing medications.
34 citations
,
November 2013 in “Breast Cancer Research and Treatment” This study found that female breast cancer survivors using aromatase inhibitors were observed to have a higher likelihood of experiencing hair loss and thinning compared to those not treated with these drugs.
34 citations
,
January 2012 in “Journal of Dermatological Science” In this mouse study, researchers found that hydrogen peroxide and monoethanolamine in hair dyes may be key contributors to dermatitis and hair loss due to oxidative stress.
34 citations
,
July 1987 in “The Journal of dermatologic surgery and oncology” This article reviews advanced dermabrasion techniques for acne scars and skin lesions, detailing patient selection and procedural steps to enhance therapeutic outcomes and avoid pitfalls, but reports no new findings.
34 citations
,
January 1977 in “American Journal of Cardiology”
34 citations
,
April 1973 in “The American journal of clinical nutrition” This study found that inadequate maternal pyridoxine during pregnancy led to lower body weight, slow physical development, and impaired neuromotor development in rat pups, with the severity increasing as pyridoxine levels decreased.
33 citations
,
November 2008 in “European Journal of Pharmaceutical Sciences” This study found that St. John's wort treatment for two weeks induced finasteride metabolism and reduced its plasma exposure in healthy men.
32 citations
,
June 2017 in “Journal of infection/The Journal of infection” This source discusses the diagnosis and treatment of Tinea capitis in children, highlighting that Trichophyton tonsurans is the prevalent cause in the UK and that terbinafine is an effective treatment option.
31 citations
,
November 2016 in “Cell Reports” This study reveals that somatosensory neurons in mouse skin exhibit structural plasticity during hair-follicle regeneration, which may temporarily impair the reliability of encoding gentle touch.
31 citations
,
September 2014 in “Journal of Pharmaceutical Sciences” This study found that Er–YAG laser treatment significantly enhanced skin absorption and follicular delivery of antialopecia drugs, suggesting a potential laser-assisted approach to treat alopecia.
30 citations
,
February 2018 in “Journal of Pharmacy and Pharmacology” This review discusses the traditional uses and pharmacological properties of Hedychium spicatum, noting that while some traditional uses are supported by scientific studies, further research on its applications is needed.
30 citations
,
June 2008 in “Dermatologic Surgery” In this study, the SAFE System for follicular unit extraction demonstrated a favorable average follicle transection rate of 6.14% and is accessible for physicians with basic technical skills, showing promise for wider adoption.
30 citations
,
March 2001 in “Environmental Health Perspectives” This review explores the significant impacts of hormonal changes within normal physiological ranges and suggests examining low-dose effects from chemicals disrupting hormonal activity; it presents no new clinical results.
30 citations
,
April 1990 in “Clinical Pharmacology & Therapeutics” This study found that coadministering minoxidil with tretinoin cream increased minoxidil absorption nearly threefold in healthy males, attributed to increased stratum corneum permeability.
29 citations
,
February 2013 in “Proceedings of the National Academy of Sciences of the United States of America” This study found that Merkel cell clusters require Frizzled6 signaling for their polarity information, while other hair follicle-associated structures align their orientation based on the hair follicle itself.
28 citations
,
September 2015 in “Wiener Klinische Wochenschrift” New skin substitutes for treating severe burns and chronic wounds are being developed, but a permanent solution for deep wounds is not yet available commercially.