6 citations,
June 2022 in “Dermatologic Therapy” Honokiol from Magnolia plants may be beneficial for treating various skin conditions and promoting hair growth.
1 citations,
February 2023 in “ACS Biomaterials Science & Engineering” The new microwell device helps grow more hair stem cells that can regenerate hair.
1 citations,
December 2022 in “Pharmaceutics” Finasteride-loaded microemulsions can effectively enhance skin delivery for treating hair loss.
1 citations,
January 2018 in “Skin appendage disorders” The complement system might be involved in the development of alopecia areata and could lead to new treatments.
Sonic hedgehog helps hair follicle stem cells grow and can effectively regenerate hair follicles.
January 2022 in “Springer eBooks” The document reviews historical studies on hair follicle neogenesis, highlighting the role of fibroblast growth factors (FGFs) in dermal condensation and hair follicle development. Key findings include FGF-2's ability to induce dermal condensations, FGF20's role in forming primary and secondary dermal condensations, and FGF9's involvement in hair follicle neogenesis post-wounding. The studies collectively underscore the importance of epithelial-mesenchymal interactions and molecular signaling pathways in hair follicle morphogenesis and regeneration.
The study investigated protein expression in forehead epidermal corneocytes to distinguish between frontal fibrosing alopecia (FFA) and androgenetic alopecia (AGA). Samples from 5 FFA patients, 5 AGA patients, and 12 controls revealed that FFA had 72 proteins significantly different from controls, with most showing lower expression, while AGA had only 3 proteins significantly different. This suggests FFA affects protein expression systemically, beyond the scalp. The findings support non-invasive monitoring of FFA through forehead epidermis protein profiling, indicating a potential for better diagnosis and treatment monitoring.
November 2022 in “Journal of Nanobiotechnology” The developed system could effectively treat hair loss and promote hair growth.
231 citations,
October 1999 in “Journal of Clinical Investigation” Activating the Sonic hedgehog gene in mice can start the hair growth phase.
176 citations,
June 2019 in “Cells” Different fibroblasts play key roles in skin healing and scarring.
133 citations,
July 2020 in “Cells” Creating fully functional artificial skin for chronic wounds is still very challenging.
79 citations,
December 2017 in “Cosmetics” The document reviewed in vitro studies on sunscreen permeation and retention, emphasizing the importance of formulation strategies to prevent systemic absorption and potential DNA damage. It discussed the effectiveness and stability of various UV filters, the impact of nanotechnology, and the use of three-dimensional human skin cultures as alternatives to animal testing. Techniques like encapsulation in lipid nanoparticles and bioadhesive nanoparticles were found to reduce skin penetration and enhance photoprotection. The review highlighted the need for standardized in vitro methods to predict in vivo performance and ensure regulatory compliance.
58 citations,
August 2015 in “The Indonesian Biomedical Journal” Different types of stem cells help maintain and heal skin.
51 citations,
August 2013 in “The Journal of experimental medicine/The journal of experimental medicine” Loss of a specific protein in skin cells causes symptoms similar to psoriasis.
35 citations,
December 2020 in “International Journal of Molecular Sciences” Mast cells likely promote skin scarring and fibrosis, but their exact role is still unclear.
31 citations,
August 2015 in “Stem Cells Translational Medicine” Human skin can provide stem cells for tissue repair and regeneration, but there are challenges in obtaining and growing these cells safely.
26 citations,
January 2007 in “Organogenesis” Bioengineering can potentially treat hair loss by regenerating hair follicles and cloning hair, but the process is complex and needs more research.
20 citations,
November 2021 in “Frontiers in cell and developmental biology” Skin organoids from stem cells could better mimic real skin but face challenges.
15 citations,
January 2023 in “Biomaterials Research” 3D bioprinting in plastic surgery could lead to personalized grafts and fewer complications.
14 citations,
May 2022 in “Asian Journal of Pharmaceutical Sciences” New hair follicle-targeting treatments show promise for hair disorders but need more research on safety and effectiveness.
14 citations,
January 2019 in “Advances in experimental medicine and biology” Skin stem cells are promising for healing wounds and skin regeneration due to their accessibility and regenerative abilities.
8 citations,
June 2023 in “Journal of clinical medicine” Nanofat shows promise for facial rejuvenation and treating skin issues but needs more research for long-term safety.
5 citations,
February 2022 in “Acta Biomaterialia” Nanomaterials can improve hair care products and treatments, including hair loss and alopecia, by enhancing stability and safety, and allowing controlled release of compounds, but their safety in cosmetics needs more understanding.
5 citations,
January 2021 in “Frontiers in cell and developmental biology” Skin cysts might help advance stem cell treatments to repair skin.
4 citations,
December 2022 in “Frontiers in Bioengineering and Biotechnology” Exosomes show promise for improving wound healing, reducing aging signs, preventing hair loss, and lightening skin but require more research and better production methods.
3 citations,
March 2023 in “Biology” Genes affecting wool fiber thickness in Angora rabbits were identified, which could help breed finer wool.
3 citations,
January 2020 in “Plastic and Aesthetic Research” Non-surgical procedures can help reduce wrinkles and stimulate skin repair by understanding skin aging at the molecular level.
2 citations,
May 2023 in “International Journal of Molecular Sciences” The TRPV3 ion channel is important for skin and hair health and could be a target for treating skin conditions.
2 citations,
September 2022 in “Cytotherapy” Fat-derived stem cells show promise for treating skin issues and improving wound healing, but more research is needed to confirm the best way to use them.
2 citations,
June 2022 in “International Journal of Molecular Sciences” Lower levels of certain genes in hair cells improve hair loss treatment outcomes.