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Chinese domestic goats have unique genetic traits due to domestication and geographic isolation.

Androgens and SARMs play a role in body mass, frailty, skin health, and hair growth, and are used in treating prostate cancer, acne, and hair loss, with potential for new uses and improved versions in the future.

Shorter CAG repeats may cause hair and skin issues, while longer ones may link to acne.

Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.

E211 G>A gene linked to lower risk of severe prostate cancer and hair loss.

The exact cause of increased 5α-reductase activity leading to hirsutism in women is still unknown.

Blocking the androgen receptor in skin cells reduces their growth response to male hormones, suggesting a possible treatment for skin conditions linked to androgens.

Certain genetic variants in the androgen receptor are linked to higher PSA levels, potentially affecting prostate cancer screening outcomes.

Certain gene variations might be linked to severe acne in women but not in men.

A genetic variant in the androgen receptor gene increases heart disease risk in women but not in men.

A new mutation linked to partial Androgen Insensitivity Syndrome and prostate cancer was found in a patient unhappy with their female gender assignment.

Removing part of the vitamin D receptor stops vitamin D from working properly.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Reduced AR gene methylation may cause early pubic hair growth in girls.

Four patients with a type of rickets and hair loss had different mutations in their vitamin D receptor gene, causing it to not work properly.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.

Finasteride side effects in young men may be linked to specific gene variations.

Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.

Changes in testosterone and estrogen receptor genes can affect how men age, influencing body fat, hair patterns, and possibly leading to skin disorders.

Scientists made a sensor that can detect a specific type of RNA related to androgen receptors quickly and accurately.

The vitamin D receptor has many roles in the body beyond managing calcium, affecting the immune system, hair growth, muscles, fat, bone marrow, and cancer cells.

Vitamin D receptor is crucial for starting hair growth after birth.

PPAR-γ may be a key target for treating alopecia areata and other skin conditions.

A specific drug can help treat Lichen Planopilaris, a condition causing permanent hair loss.

OCT binds strongly to hair sheath cells and may affect skin and hair growth with fewer side effects than vitamin D3.

The proteins transthyretin and megalin are more present in the growth phase of hair, suggesting they might affect hair health and growth.

Vitamin D receptor knockout mice have significant motor impairments but no cognitive deficits.

Androgens cause oil-producing skin cells with androgen receptors to mature and produce more oil.

Researchers developed new compounds that target the androgen receptor effectively with fewer side effects.