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Abusing steroids can damage your heart, muscles, reproductive system, liver, skin, and brain, and may increase the risk of Alzheimer's disease.

GLI1 might protect against the start of skin cancer and is not linked to cancer severity.

Women with PCOS are more likely to have skin problems like excessive hair, acne, and hair loss.

Long-term use of finasteride in women can cause hormonal changes, DNA damage, and menstrual issues.

SAHA syndrome is a condition in women involving skin and hair issues, often related to hormonal imbalances, and is treated based on the underlying cause.

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

Certain gene variations might help protect against insulin resistance and glucose intolerance in people with Polycystic Ovary Syndrome.

Capsaicin cream quickly relieved itching in two patients with brachioradial pruritus.

Retinoids are effective for skin conditions like severe acne and psoriasis but must be used with caution due to potential side effects and risks during pregnancy.

The conclusion is that tritium-labeled testosterone metabolites can be made and are better converted into dihydrotestosterone in skin cells than in prostate tissue.

Finasteride's sexual side effects not caused by androgen deficiency or SRD5A inhibition.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

RACB in barley is crucial for cell polarity and nucleus positioning, aiding fungal infection.

Most hirsutism cases are due to PCOS, and treatment focuses on lowering testosterone and blocking its effects.

Finasteride helps prevent kidney stones, but side effects need more research.

Baricitinib shows promise as a new treatment for certain skin conditions like alopecia areata.

The PLP2 gene affects cashmere fiber quality in goats and is linked to hair growth and loss.

Neuroactive steroids may affect the risk and treatment of alcohol use disorders.

Human prostate cells produce more WISP1/CCN4 when there's not enough oxygen.

Hair loss, prostate size, and urinary issues are related due to androgen effects.

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.

Spironolactone is a safe and effective treatment for reducing excessive hair growth in women.

CDP is crucial for lung and hair follicle cell development.

Eating a high-glycemic diet may worsen acne by increasing certain protein levels and expressions in the skin.

Genetics and hormones play a role in male and female hair loss, but more research is needed to fully understand it.

Restoring mitochondrial function in mice reversed their skin wrinkling and hair loss.