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Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Anticancer drugs are increasingly found in surface waters, and their long-term environmental effects are not well understood, requiring better testing methods.

Air pollution worsens skin diseases and aging by causing inflammation and oxidative stress.

PGD2 stops hair growth and is higher in bald men with AGA.

Latanoprost can make eyelashes longer, thicker, and darker.

Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.

Some vitamins and minerals like vitamin D and iron can help with certain types of hair loss, but more research is needed for others.

Thyroid hormones help hair grow, reduce hair loss, and increase hair pigment.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

The document concludes that hair is complex, with a detailed growth cycle, structure, and clinical importance, affecting various scientific and medical fields.

Chemotherapy often causes temporary hair loss, which is distressing and needs better treatment and support.

Laminin-511 is crucial for early hair growth and maintaining important hair development signals.

All-trans retinoic acid causes hair loss by increasing TGF-β2 in hair follicle cells.

The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.

Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.

Activating the Wnt/β-catenin pathway could lead to new hair loss treatments.

Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.

Blocking the virus's entry into cells by targeting certain pathways could lead to early COVID-19 treatments.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.

Wnt signaling is crucial for skin and hair development and its disruption can cause skin tumors.

Acne is a chronic disease linked to various systemic conditions and has significant psychological and social effects.

Estrogens and SERMs can help with skin aging, but their safety and effectiveness need more research.

An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.

Skin problems can be caused or worsened by physical forces and pressure on the skin.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.

Eating healthy, exercising, and taking certain supplements can help manage Polycystic Ovary Syndrome symptoms.

Eclipta alba has many health benefits and contains compounds with potential for drug development.