research A Mouse Model of Androgenetic Alopecia
Mice with human gene experienced hair loss when treated with DHT.
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research Innovative Use of Spironolactone as an Antiandrogen in the Treatment of Female Pattern Hair Loss
Spironolactone helps regrow hair in women with hair loss.
research Treatment of Androgen Excess in Females: Yesterday, Today, and Tomorrow
The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.
research Other Antiandrogens: Alternative Treatments for Acne and Hirsutism
Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.
research Androgen Receptor-Mediated Inhibition of Cutaneous Wound Healing
Blocking testosterone speeds up wound healing in males.
research Androgen Receptor-Mediated Inhibition of Cutaneous Wound Healing
Blocking testosterone speeds up wound healing in males.
research 5α-Reductase Isozymes and Androgen Actions in the Prostate
5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.
research Female Androgenetic Alopecia: New Pathophysiological Factors and Future Trends for a More Comprehensive Clinical Approach
New factors in female hair loss include genetics, hormones, stress, and inflammation; future treatments should also focus on these areas and consider the patient's emotional well-being.
research Characteristics of Androgenetic Alopecia in Asian Populations
Asian hair loss differs from Europeans; consider individual needs and psychological well-being for treatment.
research The Endocrinology of Baldness
Hormones and genetics play key roles in male and female baldness, which can affect mental health and may be linked to other health issues.
research Progressive Expression of PPARGC1α Is Associated with Hair Miniaturization in Androgenetic Alopecia
Increased PPARGC1α relates to hair thinning in common baldness.
research Intratumoral De Novo Steroid Synthesis Activates Androgen Receptor in Castration-Resistant Prostate Cancer and Is Upregulated by Treatment with CYP17A1 Inhibitors
Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.
research Men With Kennedy Disease Have a Reduced Risk of Androgenetic Alopecia
Men with Kennedy disease have less chance of hair loss.
research Androgenetic Alopecia in Men: An Update on Genetics
Androgenetic alopecia in men is genetic and linked to health issues like obesity and heart disease, with treatments including minoxidil, finasteride, and hair transplants.
research Regional Difference in Sebum Production by Androgen Susceptibility in Human Facial Skin
The T-zone on the face has more androgen receptors and produces more oil than the U-zone.
research Sex Differences in SARS-CoV-2 Infection Rates and the Potential Link to Prostate Cancer
Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.
research Trazodone By Epigenetic Mechanism Can Reverse The Post Finasteride Syndrome
Trazodone might help reverse post finasteride syndrome.
research Anti-Alopecia Activity of Coumarin Derivatives from Merremia Peltata Leaves and Their Binding to Androgen Receptors: A Molecular Study
Scopolin and scopoletin from Merremia peltata leaves may help treat hair loss and showed promising results in rabbit tests.
research Exosomes Derived From Umbilical Cord Mesenchymal Stem Cells Promote Hair Regrowth in C57BL/6 Mice Through Upregulation of the RAS/ERK Signaling Pathway
Exosomes from stem cells help hair regrowth by activating a specific signaling pathway.
research The Postnatal Offspring of Finasteride-Treated Male Rats Shows Hyperglycemia, Elevated Hepatic Glycogen Storage, and Altered GLUT2, IR, and AR Expression in the Liver
Finasteride-treated male rats' offspring had altered glucose metabolism, potentially increasing diabetes risk.
research Impact of Cernitin on Induced Chronic Prostatitis in Animal Model for Understanding Management of Lower Urinary Tract Symptoms
Cernitin™, a pollen extract, was found to significantly reduce pain and inflammation in rats with chronic prostatitis, suggesting it could be a useful alternative to certain anti-inflammatory drugs.
research New Therapeutic Approach to the Hirsute Patient
Spironolactone can reduce hair growth in women with hirsutism.
research Gender Differences in Cardiac Hypertrophy
Women generally handle heart enlargement better than men, but it's riskier for them if it occurs; hormones like estrogen offer some protection.
research Development of Prostate Cancer in a Patient with Primary Hypogonadism: Intratumoral Steroidogenesis in Prostate Cancer Tissues
Prostate cancer can progress even with low testosterone due to internal hormone production in the tumor.
research Acne: Diet and Acnegenesis
Eating dairy and high glycemic foods may increase the risk of acne.
research Recent Advances in Drug Design and Drug Discovery for Androgen-Dependent Diseases
New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.
research Connarus Semidecandrus Jack Exerts Anti-Alopecia Effects by Targeting 5α-Reductase Activity and an Intrinsic Apoptotic Pathway
Connarus semidecandrus Jack extract promotes hair growth and thickness, reduces prostate cancer cell growth, and could potentially be used as a treatment for hair loss.
research Lack of Androgen Receptor Transcriptional Activity in Human Keratinocytes
Human keratinocytes do not naturally respond to androgens.
research Intrinsic Versus Extrinsic Aging: A Histopathological, Morphometric, and Immunohistochemical Study of Estrogen Receptor β and Androgen Receptor
The study concluded that both estrogen and androgen receptors, which decrease with age, are linked to skin aging and may be hormonally regulated.
research The AR/miR-221/IGF-1 Pathway Mediates the Pathogenesis of Androgenetic Alopecia
A specific pathway involving AR, miR-221, and IGF-1 plays a key role in causing common hair loss.