This study reports two cases of severe alopecia areata showing seemingly permanent hair regrowth with a modified triamcinolone acetonide regimen involving epinephrine, and suggests a potential role for epinephrine in enhancing treatment efficacy.
July 2022 in “Singapore Medical Journal” Most children with alopecia areata improved with treatment, but those with more hair loss had worse outcomes.
March 2022 in “Journal of Survey in Fisheries Sciences” This review discusses the diverse phytochemical constituents and medicinal applications of Asteraceae family plants, noting their significance in traditional and modern medicine, but provides no new clinical results.
August 2017 in “International journal of research in dermatology” This study found that topical 0.05% betamethasone dipropionate was the most effective treatment for patients with patchy alopecia areata, with less than 25% hair loss, over a 12-week period, compared to other topical treatments.
This study utilized a pigmented human epidermal equivalent model to incorporate melanocytes into the epidermis and found enhanced differentiation potential compared to conventional in vitro systems, reflecting in vivo cellular trajectories and highlighting melanocyte-to-keratinocyte communication pathways.
May 2026 in “Discover Chemistry.” This review presents recent advancements in bio-degradable polymers made through green chemistry, highlighting eco-friendly raw materials and methods, while also identifying challenges and future research areas to enhance their sustainability and commercial viability.
This study suggests that 9-Octadecenoic acid (Z)-, 2,3-dihydroxypropyl ester from African Yam bean seeds may inhibit the human 5α-reductase II enzyme, potentially helping manage BPH, although further studies are needed.
August 2025 in “International Journal of Environmental Sciences” In this descriptive cross-sectional study, researchers observed that less than 10% of female nursing students in Dharmapuri have been diagnosed with polycystic ovarian syndrome, though many show increasing symptom prevalence and poor health-related behaviors, underlining the need for better education and regular gynecological check-ups.
This scoping review found that microneedle patches loaded with exosomes, primarily derived from mesenchymal stem cells, show promising potential for delivering exosome therapies to treat non-cicatricial alopecia, suggesting new directions for enhancing hair follicle regeneration.
August 2024 in “Journal of Home Economics Research” This source reports that among female youths in Umunneochi, common hair care products like serums, sprays, and lotions fall below average usage, and it concludes that consulting dermatologists and avoiding counterfeit products could prevent hair damage.
December 2023 in “Research and reports in urology” This case report from the authors highlights a rare diagnosis of high-grade prostate cancer in a 35-year-old man, showing strong functional recovery and no detectable PSA one year after robotic-assisted radical prostatectomy despite the usual onset being significantly later in life.
June 2023 in “International journal of pharmaceutical quality assurance” This study found that Eclipta alba extracts exhibit 5α-reductase inhibitory activity, with the methanolic extract showing a higher concentration of β-sitosterol compared to petroleum ether extract, indicating potential for treating androgenic conditions like male pattern baldness.
January 2023 in “Advances in pharmacology and clinical trials” This review highlights that human hair is a valuable biological matrix for clinical and toxicological analyses, demonstrating its applicability in detecting various active substances from different pharmacological classes.
September 2022 in “Tropical grasslands-Forrajes tropicales” This study observed that smallholder cattle farmers in West Nusa Tenggara, Indonesia using leucaena as feed managed more cattle and focused more on fattening rather than breeding, but leucaena toxicity led to illnesses such as hair loss and, in a few cases, reproductive issues.
In this observational study, men with early onset androgenic alopecia exhibited a statistically significant correlation with more severe forms of coronary artery disease compared to those without the condition.
This study explored the structure and function of lipocalin prostaglandin D synthase, revealing its dual role in substrate catalysis and as a lipophilic ligand carrier, potentially informing future drug delivery design.
January 2019 in “Clinical Dermatology Open Access Journal” This report describes two cases of extensive alopecia areata successfully treated with a combination of intralesional corticosteroids and fractionated laser, suggesting the potential of laser treatment to promote hair regrowth.
October 2017 in “Indian heart journal” Higher levels of small, dense LDL cholesterol are linked to a greater risk of heart attack in young adults.
April 2016 in “Plastic and reconstructive surgery. Global open” This article from the PRS Global Open and ASPS Education Network does not present any new research findings; it likely serves as an introductory or descriptive overview.
November 2015 in “European journal of dermatology/EJD. European journal of dermatology” This report describes a 55-year-old African woman with a 4-year history of frontotemporal alopecia and total eyebrow loss, who experienced scalp itching and had unsuccessfully undergone hair transplantation.
January 2014 in “IOSR journal of pharmacy” This case report identifies alopecia universalis as a probable adverse drug reaction to adalimumab in a patient with psoriasis and psoriatic arthritis.
June 2018 in “The Journal of Sexual Medicine” In this study, finasteride was found to significantly reduce DHT levels and affect spermatogenic markers in rats, while DA-9401 co-treatment indicated potential ameliorative effects.
October 1990 in “Archives of Dermatology” This piece describes a study designed to quantify hair density in the frontoparietal area of women without self-reported androgenetic alopecia, but it reports no results.
April 2021 in “Journal of Investigative Dermatology” This study found that oral spironolactone improved or maintained hair condition in females with scarring alopecia and female pattern hair loss, with 83% of patients tolerating the treatment well, despite some side effects like hyperkalemia and leg cramps.
451 citations
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March 2005 in “Endocrine Reviews” This paper discusses the role of steroid sulfatase in hormone-dependent tumors and highlights the development of potent inhibitors, noting the commencement of a phase I trial for one inhibitor in postmenopausal breast cancer patients.
118 citations
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July 2005 in “Journal of Ethnopharmacology” In this study, the aqueous extract of Eclipta alba and its hydrolyzed fraction showed nootropic activity and reduced stress-induced alterations in rats.
111 citations
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October 2008 in “Nature Genetics” In their study, Tim Spector and colleagues identified a new genetic association at chromosome 20p11.22 with male-pattern baldness, confirmed by the increased risk when combined with a known androgen receptor gene variant.
75 citations
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November 2009 in “Gynecological Endocrinology” This study found that both myo-inositol and metformin helped restore normal menstrual cycles in patients with PCOS, but myo-inositol appeared to be more effective in inducing pregnancy.
59 citations
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September 1994 in “The Journal of Clinical Endocrinology and Metabolism” This study found that 4 weeks of finasteride treatment significantly decreased DHT levels in bald scalp to levels similar to hair-containing scalp in men with male pattern baldness.
43 citations
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February 2020 in “Clinica chimica acta” This review discusses the role of phytochemical nanoparticles in cervical cancer therapy and reports no new clinical results; the authors highlight their potential advantages over conventional chemotherapy.