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This study demonstrated that dominant mutations in mouse gasdermin A3 disrupt mitochondrial oxidative stress regulation, suggesting a gain-of-function effect on epidermal differentiation.

This study demonstrates that the transcription factor DLX5 can promote hair follicle stem cell differentiation through regulating the c-MYC/miR-29c-3p/NSD1 axis.

This study found that using a combination of Virgin Coconut Oil and Nigella Sativa Oil improved wound healing in diabetic rats by reducing inflammation and enhancing skin thickness compared to single treatments or controls, suggesting a potentially valuable approach for managing diabetes-related wounds.

This study found that the antioxidant N-acetylcysteine attenuated ferroptosis in the uterus and placenta of a PCOS-like rat model, indicating its potential as a therapeutic strategy for PCOS-related complications.

This study found that conditional knockout of N-WASP in keratinocytes of mice led to skin barrier defects, increased immune cell infiltration, and hyperproliferation of keratinocytes, indicating its crucial role in skin homeostasis.

This study found that the n-hexane fraction from Leea indica leaves significantly increased hair growth in mice and showed potential as a natural treatment for alopecia.

This study found that N,N-dimethylglycine sodium salt promoted proliferation and migration of cultured human epidermal keratinocytes and had anti-inflammatory and antioxidant effects in vitro.

PLGA nanospheres in cosmetics improve skin and hair treatment effectiveness.

This study developed a mouse model to simulate chronic radiation-induced salivary dysfunction, revealing dose-dependent saliva reduction and glandular changes, which may help advance salivary regenerative therapies.

This study reviews the mechanisms and recent findings of immunotherapies for NSCLC, highlighting their potential to improve treatment outcomes and reduce side effects compared to traditional therapies.

This study found that overexpression of NSD3 in the mammary gland of transgenic mice led to mammary hyperplasia, dysplasia, and invasive ductal carcinoma, mirroring patterns seen in human breast cancer.

This study suggests that two approved drugs may inhibit the SARS-CoV-2 helicase based on significant activity in laboratory models, offering hope for potential COVID-19 treatments.

This study found that Golvatinib, Gliquidone, and Dihydroergotamine may inhibit the binding of SARS-CoV-2's Nsp1 protein to the host ribosomal subunit, suggesting potential as treatments against COVID-19 variants.

This article reviews skin toxicity classifications and management in patients undergoing molecularly targeted therapy, noting significant dermatotropic side effects associated with Epidermal Growth Factor Receptor Inhibitors.

In this study, the authors review how epigenetic regulation influences the role of iPSC-derived neural stem/progenitor cells in spinal cord injury therapy, highlighting challenges in the cells' generation, differentiation, and transplantation, and the effect of therapeutic tools on these processes.

This review provides an overview of androgenetic alopecia, detailing its causes, diagnostic methods, and current treatments, noting that combination therapies show promise but newer options like cell-based treatments require more research.

This meta-analysis suggests that combining Kang-ai injection with platinum-based chemotherapy may improve tumor response, performance status, immune functions, and reduce adverse reactions in patients with advanced non-small cell lung cancer.

This study found that paclitaxel poliglumex showed limited effectiveness and was relatively well tolerated in post-menopausal women with advanced NSCLC, suggesting further testing of this treatment may not be justified.

This study found that while the carboplatin-paclitaxel regimen for advanced lung cancer is more affordable than newer treatments and maintains a good performance status, it significantly increases risks of alopecia and peripheral neuropathy.

This case report details a 13-year-old Thai boy with Hutchinson-Gilford progeria syndrome, who presented with cardiovascular complications, including coronary artery calcification and non-ST-segment elevation myocardial infarction.

The study reported that Demodex musculi infestation was notably higher in immunodeficient mice, while infested immunocompetent mice, particularly the BALB/c strain, showed increased IgE levels and developed alopecia over time.

This study reviews the significant prevalence of organic etiologies, especially vascular causes, in erectile dysfunction among men under 40 and emphasizes thorough evaluation and consideration of treatment options like exercise and PDE-5 inhibitors.

This guideline outlines the management of systemic lupus erythematosus in adults but reports no new clinical findings.

This review discusses the pharmacology and toxicology of cyclooxygenase in skin, highlighting its role in inflammation, wound healing, and tumorigenesis, without presenting new clinical results.

This article suggests that modern lifestyle changes, including diet, stress, and chronic anti-inflammatory medication use, may disrupt the natural process of inflammation resolution, increasing vulnerability to chronic disease.

This review examines the patent literature on AKR1C3 inhibitors and suggests that although numerous potent inhibitors exist, further preclinical optimization is necessary before assessing their therapeutic potential in human diseases.

This article discusses the history and terminology of toxic epidermal necrolysis but reports no new clinical results.

This study found that nanoemulsion-based formulations, such as nanoemulgel and NFs, might serve as promising topical delivery systems for treating inflammatory diseases, potentially offering an alternative to traditional nonsteroidal anti-inflammatory drugs, which are associated with adverse effects.

This review discusses the role of tumor suppressors in controlling tumor-associated inflammation and suggests that targeting this inflammation may counteract the effects of tumor suppressor loss.

This report describes an 11-year-old boy with Netherton syndrome who developed Cushing syndrome after using low-potency hydrocortisone ointment extensively, highlighting caution with long-term topical treatments in such conditions.