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In this study, PEVIII, a nanocomposite chitosan-coated vesicle containing both α-hederin and hederacoside C, demonstrated notable antibacterial activity against Pseudomonas aeruginosa in a keratitis model, showing significant lesion reduction, tissue improvement, and decreased bacterial load and inflammatory markers compared to other treatments.

In this animal study, AGO (agomelatine) effectively alleviated testosterone-induced benign prostatic hyperplasia in rats by reducing oxidative stress and inflammation, indicating its potential as a therapeutic option for managing BPH through specific signaling pathways.

This study found that treating secondary hair follicle stem cells from Arbas cashmere goats with 10 μg/mL quercetin for 48 hours significantly boosted cell proliferation and reduced apoptosis by activating several signaling pathways, suggesting a potential strategy to enhance cashmere production.

In this study, black wolfberry ferment was found to promote hair regrowth in mice with androgenetic alopecia by increasing hair weight, follicle count, and skin thickness, potentially through PI3K/AKT, NF-kappa B, and MAPK signaling pathways.

The researchers reported that DHT may reduce the inflammatory responses induced by C. acnes in androgen-sensitive human sebocyte cells, suggesting a potential link between androgens and infection in sebaceous disorders.

This study found that bioelectric and biochemical signaling mechanisms coordinate collective cell movement during chicken feather bud morphogenesis, suggesting a potential new angle for research in skin development and wound healing.

This study suggests that human hair follicles may operate their own Cori cycle, synthesizing glycogen from lactate under conditions of lactic acidosis.

This review discusses the interplay between signaling/transcription factor-mediated and epigenetic mechanisms in skin development and regeneration, highlighting the need for further exploration of epigenome reorganization in these processes.

This study found that Chrysanthemum zawadskii extract may promote hair growth by inducing an earlier conversion of telogen to anagen and increasing the proliferation of dermal papilla cells in mice and human hair follicle cultures.

This study found that human umbilical cord blood-derived mesenchymal stem cells (hUCB-MSCs) significantly prevented hair loss induced by dexamethasone in a mouse model and enhanced cell proliferation in human hair follicle cells, suggesting a protective effect against stress-related hair loss.

This study found that exogenous glutamic acid can promote hair growth and keratinocyte proliferation, suggesting a novel signalling pathway in the skin.

This study suggests that LONRF1 may play a vital role in linking oxidative damage responses and tissue remodeling during wound healing, with distinct mechanisms in senescent and non-senescent cells.

This study reviews how oxidative stress affects hair follicle development and hair growth, discusses antioxidant-based treatments for hair loss, and evaluates natural antioxidant products that promote hair growth, emphasizing the need for further research due to existing limitations.

This study found that Eucommia ulmoides bark extract shows potential antioxidant and hair follicle-support properties in vitro and in vivo, but further validation is needed to confirm these effects.

This review highlights exosomes as a promising treatment for skin damage from UV light, infrared radiation, burns, and disorders due to their anti-inflammatory properties, ability to induce macrophage polarization, and acceleration of skin repair and regeneration.

This study found that astilbin downregulates effector CD4+ T cell activities through the CYP1B1/ROS/PPARγ pathway, suggesting its potential use in treating inflammation.

This study found that autophagy is impaired in Birt-Hogg-Dubé syndrome-associated renal tumors and identified that the FLCN protein interacts with key autophagy components regulated by ULK1.

This study reported that inhibiting the JAK-STAT pathway with baricitinib restored cellular homeostasis, delayed senescence, and reduced proinflammatory markers in Hutchinson-Gilford progeria syndrome cell models.

This review highlights the mixed roles of testosterone in COVID-19, noting both potential benefits through anti-inflammatory effects and risks due to increased virus entry, with low testosterone linked to increased severity.

This ex vivo study reported that melatonin significantly improved certain aging biomarkers in aged human skin, including reduced mTORC1 activity, increased fibrillin-1, and enhanced collagen and elastic fiber organization, though other key biomarkers remained unchanged.

This study found that adipose-derived exosomes may inhibit adipogenesis and lipogenesis in adipose-derived stem cells by activating Hedgehog signaling, suggesting potential applications for improving wound healing in obesity.

This study found that chitosan nanoparticle-encapsulated Cordyceps militaris significantly reduced inflammation and oxidative stress in particulate matter-exposed mice, suggesting potential use for managing lung inflammation.

This review highlights the promise of small extracellular vesicles (sEVs) as biomarkers for sepsis, emphasizing their potential to improve early detection and guide therapeutic decisions by reflecting the immune status and pathogen presence in patients.

This study reported that atelocollagen enhances collagen synthesis and reduces oxidative stress in aged skin by increasing glycine uptake through GlyT1, resulting in improved skin elasticity and collagen density in aged mice, with effects superior to glycine alone.

This study found that Ishige sinicola ethanol extract and its butanol fraction can protect against lipopolysaccharide-induced muscle atrophy in C2C12 myotubes through antioxidant and anti-inflammatory activities.

This study found that adding keratin to a collagen hydrogel improved keratinocyte differentiation compared to a pure collagen hydrogel, particularly when calcium was also present in the media.

This study found that hair follicle-derived mesenchymal stem cells can alleviate pyroptosis and improve ulcerative colitis symptoms in mice, suggesting potential new treatments for the condition.

In this study, Eremochloa ophiuroides-derived fractions were found to significantly promote hair regrowth in a mouse model, demonstrating effects comparable to minoxidil and suggesting potential as natural hair growth agents through modulation of follicular activation markers and growth-regulatory factors.

This study found that Grateloupia angusta extract improved wound healing by promoting matrix production and pro-angiogenic activity in cell cultures and enhanced early wound repair in a mouse skin incision model.

This study found that 3-hydroxypropionic acid improved the function of hair follicle cells under oxidative stress, suggesting potential as a treatment for stress-related hair loss.