August 2023 in “Scientific reports” In this study, researchers differentiated human induced pluripotent stem cells into dermal papilla-like cells and observed gene expression dynamics during five stages of dermal differentiation, demonstrating the potential of these cells to interact with epidermal cells in functional assays.
7 citations
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July 2023 in “International Journal of Molecular Sciences” In this study, human nucleus pulposus cells treated with hyaluronic acid showed increased proliferation and reduced oxidative stress compared to those treated with EDTA-PBS, suggesting a potential role for hyaluronic acid in enhancing intervertebral disc therapy.
43 citations
,
February 2020 in “Clinica chimica acta” This review discusses the role of phytochemical nanoparticles in cervical cancer therapy and reports no new clinical results; the authors highlight their potential advantages over conventional chemotherapy.
12 citations
,
November 2015 in “Cell Death & Differentiation” This study found that immune cells, including T cells and macrophages, significantly influence stem cell behavior and tissue regeneration by secreting cytokines and inflammatory factors in mice.
60 citations
,
January 2023 in “Biogerontology” This review examines testosterone's role in male health and aging but reports no new clinical results; the authors highlight the need for further research on optimal testosterone levels to prevent age-related conditions.
January 2017 in “Elsevier eBooks” This chapter discusses charnolopharmacotherapeutics for various medical conditions and suggests antioxidant-loaded nanoparticles may improve treatment by enhancing central nervous system delivery and inducing charnolophagy.
252 citations
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February 2018 in “npj Regenerative Medicine” This review explores recent advances in understanding molecular mechanisms of tissue regeneration in mammals and suggests potential therapeutic targets, but it reports no new clinical results.
191 citations
,
September 2011 in “Cell stem cell” This study found that polycomb-group-mediated repression plays a key role in regulating hair follicle stem cell states and lineage progression by distinct mechanisms in adult mouse skin.
119 citations
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March 2020 in “Frontiers in Bioengineering and Biotechnology” This review provides an overview of recent tissue engineering and regenerative medicine developments in Asia, highlighting significant advances, representative research achievements, and discussing future directions, without presenting new research results.
91 citations
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August 2014 in “Development” This review discusses how circadian clocks may influence diverse physiological functions beyond their established role in daily timekeeping, but it reports no new experimental findings.
87 citations
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July 2018 in “Biochimica et Biophysica Acta (BBA) - Molecular Cell Research” This review discusses the essential roles and complex regulation of PP2A in various physiological processes and reports no clinical results; the authors highlight the need for further mouse model research to explore PP2A's therapeutic potential.
76 citations
,
July 2019 in “Cellular and Molecular Life Sciences” This article reviews the role of stem cells in tissue development, tumor formation, and organoid generation, and highlights the potential of epigenetic regulation in advancing regenerative medicine and cancer treatment, without presenting new experimental results.
45 citations
,
September 2012 in “Life Sciences” This study observed that Aconiti Ciliare Tuber extract may promote hair growth in mice by activating the Wnt/β-catenin signaling pathway.
16 citations
,
July 2020 in “Advanced functional materials” This review discusses the development and application of cell-derived matrices in regenerative medicine and disease modeling, presenting various fabrication techniques and future perspectives, but reports no new results.
13 citations
,
December 2024 in “Cellular and Molecular Life Sciences” This study reviews recent advancements in understanding caspases, highlighting their roles beyond apoptosis in cancer, inflammation, and neurological disorders, and discusses the potential and challenges of targeting caspases for therapeutic purposes.
12 citations
,
November 2020 in “Journal of Dermatological Science” In this study, miR-324-3p was found to promote differentiation and migration in cultured keratinocytes and is highlighted as a potential target for treating androgenic alopecia.
9 citations
,
December 2020 in “International Journal of Medical Sciences” This article reviews the development and use of induced pluripotent stem cell models and artificial organoids for studying neurodevelopmental disorders, but it reports no new clinical findings.
5 citations
,
September 2011 in “Cell stem cell” This study found that histone methylation patterns in hair follicle stem cells differ from those in embryonic stem cells.
January 2018 in “Stem cell biology and regenerative medicine” This review discusses how the nuclear lamina integrates biochemical and mechanical signals to influence gene expression and skin homeostasis, but reports no new clinical results.
January 2008 in “Durham e-Theses (Durham University)” This study observed that stem cells from the hair follicle dermis share similarities with bone marrow-derived mesenchymal stem cells and have potential to form neural-like cells under specific conditions.
1 citations
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April 2022 in “Frontiers in Bioengineering and Biotechnology” This study found that mouse astrocytes formed cell spheres on agarose surfaces, acquired stem cell-like features, and their derived stem cells effectively differentiated into neurons that helped regenerate damaged nerves.
10 citations
,
January 2019 in “The Nurse Practitioner” This article reviews diagnostic and treatment guidelines for polycystic ovary syndrome, discussing how nurse practitioners can enhance patients' quality of life through education; it reports no new clinical results.
3 citations
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March 2018 in “Journal of Continuing Education in Nursing” This study found that a continuing education program significantly improved rural nurse practitioners' knowledge about assessing, diagnosing, and managing PCOS.
January 2016 in “cIRcle (University of British Columbia)” This literature review discusses the need for a clinical practice guideline to help Canadian Nurse Practitioners in diagnosing and managing PCOS, noting its complexity and lack of existing guidelines.
June 2026 in “Health Nanotechnology” This narrative review suggests that nanoformulated phytochemicals hold promise for managing polycystic ovarian syndrome, but their efficacy and safety compared to standard treatments require further validation through clinical studies.
This study found that CPA-loaded nanoparticles, particularly SLN formulations, increased CPA epidermal penetration compared to a conventional cream and may reduce side effects in treating androgen-dependent conditions.
This chapter reviews the challenges and future prospects of using nanotechnology and phytochemistry in developing safe, effective, and precision-based therapies for Polycystic Ovary Syndrome, without reporting new clinical findings.
This chapter reveals how nano-antioxidants and immune-modulatory agents could offer innovative treatment strategies for PCOS by addressing the inflammation and immune system dysregulation often overlooked in traditional hormonal treatments.
4 citations
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February 2023 in “Frontiers in Oncology” In this study, Nano-Pulse Stimulation Therapy successfully cleared up to 91% of melanoma tumors in mice with less skin damage compared to cryoablation, which cleared up to 66% of tumors.
May 2026 in “Advanced Pharmaceutical Bulletin” In this study, black cumin oil-based nanostructured lipid carriers enhanced the delivery and effectiveness of fluticasone for psoriasis in a mouse model, improving skin targeting, inflammation reduction, and permeability compared to standard cream.