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Notch1 signaling is impaired in hidradenitis suppurativa, affecting skin and hair cells.

Two microRNAs affect hair follicle development in sheep by targeting specific genes.

The Notch signaling pathway is important for hair follicle development and could help create treatments for hair disorders.

Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.

Stromal stem cells may help heal wounds by becoming structural cells or affecting the immune system, but more research is needed to understand how.

Mitochondrial reactive oxygen species are essential for skin and hair development.

Melanocyte stem cells in hair follicles are key for hair color and could help treat greying and pigment disorders.

The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.

Stem cell niches are crucial for regulating stem cell renewal and differentiation, and understanding them can help in developing regenerative therapies.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

Stem cell niches support, regulate, and coordinate stem cell functions.

Hair growth and development are controlled by specific signaling pathways.

Understanding hair growth involves complex interactions between molecules and could help treat hair disorders.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Mutations in the RBPJ gene cause Adams-Oliver Syndrome.

The Hedgehog signaling pathway is important for skin and hair growth and can lead to cancer if it doesn't work right.

The study found key genes and pathways involved in cashmere goat hair growth stages.

Keratin 79 marks a new group of cells that are key for creating and repairing the hair follicle's structure.

Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.

Different skin stem cells help heal wounds, with hair follicle cells becoming more important over time.

GRHL3 is important for controlling gene activity in skin cells during different stages of their development.

Desmoglein 4 is controlled by specific proteins that affect hair growth.

STAT5 activation is crucial for starting the hair growth phase.

The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.

Acne is significantly influenced by genetics, and understanding its genetic basis could lead to better, targeted treatments.

Gene therapy, especially using atoh1, shows promise for creating functional sensory hair cells in the inner ear, but dosing and side effects need to be managed for clinical application.

Cashmere and milk goats have different hair growth cycles and gene expressions, which could help improve wool production.

The document concludes that certain mutations may contribute to the inflammation in hidradenitis suppurativa and suggests that targeting TNFα could be a treatment strategy.

The environment around melanocyte stem cells is key for hair regeneration and color, with certain injuries affecting hair color and potential treatments for pigmentation disorders.

Androgenetic alopecia is mainly caused by genetic factors and increased androgen activity, leading to hair follicle miniaturization.