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Overexpressing a specific enzyme in mice causes hair loss and female infertility.

Mutations in the vitamin D receptor cause hereditary vitamin D-resistant rickets, leading to poor bone health and requiring high calcium doses for treatment.

The right amount of retinoic acid is essential for normal hair growth and development.

Pmg-1 and Pmg-2 are new genes important for skin and mammary gland development.

The AVET system effectively delivers genes to human keratinocytes and may help treat skin diseases.

Increasing miR-149 reduces hair follicle stem cell growth and hair development by affecting certain cell growth pathways.

Removing part of the vitamin D receptor stops vitamin D from working properly.

Aging alone rarely causes significant hair loss; hormones are a bigger factor.

LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.

The research found that the molecule lncRNA-H19 helps hair follicle cells grow by affecting certain cell pathways in cashmere goats.

A new mutation in the hairless gene causes hair loss and skin wrinkling in mice.

AXR3 and SHY2 genes control the growth and timing of root hair development in plants.

Researchers found key regions in the mouse hairless gene that control its activity in skin and brain cells, affecting hair follicle function.

The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.

The Wnt signaling pathway is not a major factor in the development of keratoacanthoma, a type of skin tumor.

Sex steroids affect the MafB gene differently in male and female hamsters.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Olive oil compounds may help prevent cancer in animals, but human results are mixed.

Fatty acid transport protein 4 is essential for skin and hair development.

S100A4 and S100A6 proteins may activate stem cells for hair follicle regeneration and could be potential targets for hair loss treatments.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Ziziphus jujuba Mills may have health benefits, but more research is needed to confirm its safety and effectiveness.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

ECM1-modified stem cells can effectively treat liver cirrhosis.

VDUP1 is found in skin and hair follicles, interacts with sciellin, and may help regulate skin cell differentiation.

Male pattern baldness involves hormone-related hair thinning, shorter hair, and inflammation.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

Mice genetically modified to produce more Del1 protein had faster hair regrowth.

Fat tissue stem cells show promise for repairing different body tissues and are being tested in clinical trials.