8 citations
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March 2011 in “Endocrine” In this study, researchers identified a novel p.R50X mutation in the vitamin D receptor gene, linked to hereditary vitamin D-resistant rickets in two siblings.
January 2010 in “JOURNAL of SIBERIAN MEDICAL SCIENCES” This study found indications of phosphorus-calcium exchange abnormalities in children with chronic renal disease before kidney insufficiency, suggesting that early diagnostic methods like ultrasonic osteodensitometry could be beneficial.
13 citations
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April 1964 in “PubMed” This study found no significant differences in phosphatide distribution between normal and cancerous mouse epidermis during different stages of growth, despite variations in total phosphatide levels.
1 citations
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November 2022 in “Diagnostics” This case report identifies a 32-year-old woman with undiagnosed PHPT-1a who exhibited complete pseudo-anodontia and persistent patchy alopecia areata, suggesting these may be new nonclassical features of a GNAS pathogenic variant.
31 citations
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February 1972 in “Experientia” This study found that the diphosphonate ethan-1-hydroxy-1,1-diphosphonat was the most effective compound in preventing calcifications in rats induced by DHT, compared to other phosphatase inhibitors and polyphosphates tested.
May 2025 in “Hormone Research in Paediatrics” This case study described a girl with vitamin D-dependent rickets type 2A who developed long-standing tertiary hyperparathyroidism, yet this did not hinder the healing of her rickets or normalization of hypophosphatemia; high doses of intravenous calcium were pivotal for recovery.
8 citations
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December 1981 in “Journal of The American Academy of Dermatology” This review addresses clinical findings in parathyroid disease and discusses the metabolism of calcium, phosphorus, vitamin D, and parathyroid hormone, reporting no new results.
October 2025 in “Journal of the Endocrine Society” In this case report, an 80-year-old woman experienced elevated alkaline phosphatase levels due to the use of Viviscal hair supplements. Her levels returned to normal after discontinuing the supplement, highlighting the need for clinicians to consider supplements as potential causes of abnormal lab results.
50 citations
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January 1941 in “Annals of Internal Medicine” Idiopathic hypoparathyroidism is rare and can be managed with dihydrotachysterol.
January 2025 in “JCEM Case Reports” This report describes a 27-year-old patient with Ehler-Danlos syndrome who also presented with hypophosphatasia and mastocytosis, and suggests enzyme replacement therapy might alleviate symptoms in such overlapping genetic conditions.
June 2026 in “World Journal of Clinical Pediatrics” This study highlights the importance of recognizing non-nutritional forms of rickets, which can manifest with subtle symptoms like alopecia and cataracts, and emphasizes that a comprehensive diagnostic approach, including genetic testing, can improve management and treatment outcomes.
170 citations
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May 1979 in “The journal of pediatrics/The Journal of pediatrics” This report describes two sisters with rickets and alopecia unresponsive to high doses of vitamin D2, where oral phosphorus supplements led to significant clinical improvement.
October 2023 in “Journal of the Endocrine Society” This case report describes ALP elevation in a patient with severe OA that normalized after bilateral knee replacements, highlighting a potential link between OA and ALP levels.
21 citations
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October 2023 in “The Journal of Physical Chemistry C” This study used theoretical calculations to show that phosphates strongly bind to cerium dioxide surfaces in various stable configurations, with spectral signatures identifiable in the infrared and Raman spectra, informing future experimental efforts in controlling the enzymatic activity of ceria nanoparticles.
1 citations
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September 2018 in “Apollo (University of Cambridge)” In this study, phosphorus starvation in Arabidopsis thaliana roots strongly affected stress-induced cytosolic calcium ion modulations, which were reversible with phosphorus resupply.
January 2024 in “Arquivos de Neuro-Psiquiatria” This case study reported on a 49-year-old male with muscle weakness and low potassium levels, suggesting a diagnosis of thyrotoxic hypokalemic periodic paralysis.
January 2024 in “Wiadomości Lekarskie” This study reports a successful combination treatment for phospho-organic compound poisoning, using standard therapy with atropine and toxogonin along with exogenous cholinesterases via blood transfusion, showing positive outcomes in patients whose endogenous cholinesterase levels dropped to 20%.
10 citations
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April 1965 in “Journal of Nutrition” Changing mineral levels in rats' diets can prevent kidney stones, affect hair growth, and influence weight gain.
May 2021 in “Journal of the Endocrine Society” This case report describes the rare association of an ovarian Leydig cell tumor and primary hyperparathyroidism in a postmenopausal woman, highlighting the importance of considering rare causes in patients with virilizing symptoms.
35 citations
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February 2012 in “The New England Journal of Medicine” Early diagnosis and treatment of TPP can prevent complications.
3 citations
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April 2017 in “Medicine” This case report describes a rare instance of pediatric idiopathic hypoparathyroidism in an 11-year-old Saudi boy, characterized by extensive cranial calcifications beyond the basal ganglia, with no other neurological abnormalities.
May 2021 in “Journal of the Endocrine Society” This case report describes severe hypothyroidism exacerbated by nephrotic syndrome in a 62-year-old woman, with a diagnosis of membranous nephropathy linked to significant proteinuria.
15 citations
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March 1987 in “Phycologia” This study found that phosphorus limitation in Chaetophorales strains led to enhanced hair formation and increased phosphatase activity, suggesting a significant relationship between phosphorus status and morphology.
This study found that holding abatacept infusions for four weeks or longer before elective hip or knee arthroplasty did not reduce the risk of post-operative infections or readmissions.
1 citations
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July 2016 in “Nottingham ePrints (University of Nottingham)” This study developed mathematical models to simulate phosphate uptake in rice and Arabidopsis, suggesting a phosphate-sensitive repressor could regulate PHO2 mRNA levels, and highlighting potential targets and traits for improving phosphorus-use efficiency.
January 2024 in “Wiadomości Lekarskie” This case study reports that bisphosphonate therapy, used to treat osteoporosis, can lead to jawbone necrosis, as demonstrated in an 82-year-old patient who experienced severe complications requiring surgical intervention. The authors recommend comprehensive dental care before and avoidance of invasive procedures during bisphosphonate treatment.
546 citations
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February 2008 in “PLANT PHYSIOLOGY” This study found that overexpression of OsPHR2 in rice leads to increased phosphate accumulation and root architecture changes even under phosphate-sufficient conditions.
216 citations
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June 2015 in “PLANT PHYSIOLOGY” This study found that OsPHR3 overexpression in rice led to significant tolerance to low-phosphorus stress and normal growth under normal conditions, suggesting its potential for improving phosphorus uptake efficiency.
21 citations
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January 1997 in “Nephron” In this study, two dialysis patients with high plasma silicon levels exhibited symptoms like painful skin eruptions and unusual hair growth, suggesting silicon may influence calcium metabolism similarly to aluminum.
20 citations
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November 1968 in “The Lancet” This study found that during dialysis, lower plasma-potassium levels were associated with hyperglycemia, suggesting potassium correction is vital when using glucose-rich dialysate.