3 citations
,
November 2010 in “Rheumatic Diseases Clinics of North America” This article reviews how normal pregnancy changes can mimic rheumatologic disorders, emphasizing the importance of distinguishing these from true autoimmune inflammation, but reports no new evidence.
124 citations
,
February 2018 in “Nature Reviews Genetics” This review covers recent findings on stem cell plasticity under normal and cancerous conditions but presents no new experimental results, highlighting implications for regenerative medicine and cancer treatments.
February 2010 in “ePrints Soton (University of Southampton)” This research found that androgen bioactivity plays a role in normal female sexual differentiation, suggesting females develop within a significant androgenic environment, with implications for understanding conditions like congenital adrenal hyperplasia.
176 citations
,
January 2003 in “Journal of Investigative Dermatology” This review summarizes the roles of bone morphogenetic proteins in the development and regulation of normal and diseased skin, but it does not provide new clinical results.
31 citations
,
September 2014 in “International Journal of Dermatology” This article reviews anthralin's pharmacology, mode of action, and its use for psoriasis and other dermatoses, but reports no new clinical results.
2 citations
,
May 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that sebaceous glands in the skin are primarily renewed by their own stem cells during normal conditions, but after injury, they regenerate through stem cells from hair follicles, highlighting stem cell plasticity and regeneration capabilities.
94 citations
,
February 1994 in “The journal of investigative dermatology/Journal of investigative dermatology” This study concluded that epidermal growth factor may induce a 'catagen-like' phase in human hair follicles by disrupting normal cellular proliferation and migration patterns.
50 citations
,
October 1986 in “European journal of pediatrics” This case study reported that absence of alopecia does not reliably predict responsiveness to vitamin D treatment in Vitamin D-dependent rickets type II, as demonstrated by a patient with normal hair growth who showed extreme resistance.
37 citations
,
July 2016 in “Current Opinion in Cell Biology” This review summarizes recent discoveries about how tissue-resident stem cells interact with their environments during normal conditions and after injury, without reporting new results.
11 citations
,
March 2020 in “American Journal of Medical Genetics Part A” This study identified a novel homozygous EDNRA variant linked to Oro-Oto-Cardiac Syndrome and showed that EDNRA signaling is essential for normal craniofacial and cardiovascular development.
10 citations
,
January 2019 in “Journal of Chromatography B” This study used a newly validated method to find that one-year finasteride treatment resulted in no significant differences in urinary androgen and prostaglandin levels between male pattern baldness patients and normal controls.
1 citations
,
February 2018 in “The Journal of Sexual Medicine” This study found that young men with post-finasteride syndrome may experience erectile dysfunction due to potential histologic changes in penile tissue, despite having normal penile Doppler hemodynamics.
September 2009 in “European Urology Supplements” This study demonstrates that a new Adaptive Modulation and Coding method can improve control performance in Communication-Based Train Control systems using WLAN by reducing average delay through effective transmission mode selection.
62 citations
,
August 2018 in “Frontiers in Endocrinology” This review discusses the physiological roles of ovarian androgens in follicle development and atresia, emphasizing their contributions to polycystic ovary syndrome and normal follicle maturation but provides no new clinical results.
34 citations
,
January 2014 in “International Journal of Trichology” This study reported that polarized dermoscopy was better for visualizing vascular patterns, scaling, and reticular pigmentation, while nonpolarized mode better documented features like black dots and tapered hair in various hair and scalp conditions.
13 citations
,
September 2019 in “EBioMedicine” This study found that Secretory Phospholipase A2-IIA (sPLA2-IIA) promotes proliferation through JNK/c-Jun signaling, distinctively affecting normal stem cells and cancer cells, suggesting it as a potential target for cancer treatment.
9 citations
,
December 1981 in “International Journal of Dermatology” The document concludes that early diagnosis is key for treating common baldness in women, but reassurance is often the best approach as hair thinning can be a normal part of aging.
May 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, primary cilia were found to contribute to meibomian gland enlargement and lipid production, though they are not necessary for normal gland development.
This study suggests that raising the lower normal serum ferritin level to 50 ng/mL may improve organ functions even when hemoglobin levels are normal.
17 citations
,
April 1972 in “PubMed” Minoxidil lowers blood pressure and spreads throughout the body in normal rats.
375 citations
,
June 2013 in “Biochimica et biophysica acta. Molecular cell research” This review examines the process of cornification as a mode of programmed cell death and outlines how keratinocytes activate anti-cell death mechanisms to maintain epidermal homeostasis, but reports no new results.
69 citations
,
August 1995 in “Annals of Plastic Surgery” This study showed that ultrapulse carbon dioxide laser ablation can precisely remove rabbit skin without scarring, facilitating normal skin and hair restoration within one month.
1533 citations
,
October 2008 in “Endocrine reviews” This research highlights that engineered mice lacking the vitamin D receptor show multiple health issues similar to human vitamin D deficiency, underscoring the widespread impacts of the vitamin D endocrine system.
180 citations
,
January 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” This study observed that vitamin D receptor knockout mice exhibit impaired epidermal differentiation and progressive hair loss, suggesting the importance of the vitamin D receptor in normal skin and hair follicle development.
35 citations
,
January 2006 in “Journal of Dermatological Treatment” This review found little evidence supporting zinc as a first-line treatment for dermatological conditions, except in cases of systemic zinc deficiency, and suggests further research is needed.
24 citations
,
September 1985 in “Journal of The American Academy of Dermatology” The report suggests a possible link between hair loss and hidden scalp tumors but states more evidence is needed to confirm this.
9 citations
,
May 2021 in “Frontiers in aging neuroscience” This study found that long-term use of triterpenoids from Ganoderma lucidum may improve brain function and alleviate aging-related issues in normal and Alzheimer's mouse models.
4 citations
,
January 1989 This paper reviews the principles and challenges of cytotoxic drug therapy in cancer treatment, including effects on normal tissues, drug resistance, administration methods, and the clinical role of chemotherapy, without reporting new experimental results.
1 citations
,
July 2024 in “Frontiers in Pharmacology” In this study, a pregnant woman inadvertently exposed to spironolactone delivered a healthy male infant with normal genitalia, highlighting the need for more research on the safety of spironolactone and new-generation mineralocorticoid receptor antagonists during pregnancy.
1 citations
,
October 1984 in “Clinics in dermatology” This article discusses the psychological impact of skin imperfections and suggests establishing a Cosmetic Dermatology Service within public health systems to address these issues ethically.