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The nature of the side chain in RU 58841 derivatives greatly affects its AR affinity, with the N-(iodopropenyl) derivative 13 showing the highest AR binding affinity, suggesting its potential for developing high-affinity radioiodinated AR radioligands.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

Men with higher androgen levels may have severe COVID-19 symptoms, but those on antiandrogen therapy are less likely to contract the virus and have milder symptoms. Anti-androgen drugs could potentially treat COVID-19, but more research is needed.

RU 58841 may treat acne, hair loss, and excessive hair growth.

Flutamide rarely causes liver toxicity in prostate cancer patients.

The more lipophilic the progesterone derivative, the better it binds to androgen receptors and has antiandrogenic effects.

Birth control pills help treat acne, especially when caused by excess male hormones, and are safe to use with antibiotics.

Tamoxifen effectively treats gynecomastia without causing impotence.

Hormonal treatments are effective as a second-line option for moderate-to-severe acne in females, but should be used with caution due to health risks.

Finasteride may cause kidney damage.

Hormonal therapy changes skin and hair in transgender patients, who need better researched dermatologic care.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Gynecologists should provide comprehensive care for transgender patients, including mental health evaluation, hormone therapy, and surgical options, while monitoring for side effects and ensuring patient safety.

Nanoparticulate systems improve drug delivery by controlling release, protecting drugs, changing absorption and distribution, and concentrating drugs in targeted areas.

Scutellaria baicalensis extract and baicalin may help prevent hair loss.

Rice bran extract might help prevent hair loss.

New treatments for skin conditions related to the sebaceous gland are being developed based on current research.

The document concludes that hormone therapy is essential for treating gender dysphoria, with specific drugs and monitoring protocols recommended for safety and effectiveness.

Early diagnosis and treatment of PCOS in teenagers can help prevent more severe adult PCOS.

Birth control pills increase certain receptor activities in female gerbil prostate glands and can lead to prostate changes.

Accurate diagnosis and timely, tailored treatments improve outcomes in obstetrics and gynecology.

Avicennia Marina extract and avicequinone C can reduce hair loss hormone production and increase hair growth factors, suggesting they could be used to treat androgenic alopecia.

A new, efficient method has been developed to detect darolutamide and thalidomide, drugs used for certain hair loss and prostate cancer treatments, in pharmaceuticals and body fluids.

Riboflavin 5′-phosphate (FMN) shows potential for treating androgen-related conditions but may be limited in treating prostate cancer.

The document discusses a young boy with autism and early puberty but does not provide a conclusion on managing his behavior.

Proxalutamide significantly lowered hospital admissions for male COVID-19 patients compared to a placebo.

Minoxidil and finasteride are the best for non-scarring hair loss; more research is needed for scarring hair loss treatments.

Two drugs, finasteride and minoxidil, are approved for hair loss treatment, but new therapies are being developed.

Gefitinib and Sasam-Kyeongokgo together significantly reduce cancer growth and improve immune response in mice.