4 citations
,
May 2025 in “Stem Cell Research & Therapy” This review explores the potential of extracellular vesicle therapy as a novel strategy to delay intervertebral disc degeneration and enhance tissue repair, by modulating key pathogenic mechanisms, with a focus on the molecular components and bioengineering modifications of extracellular vesicles.
5 citations
,
November 1992 in “Current problems in dermatology” This review discusses the role of glucocorticoids in treating severe inflammatory disorders and highlights their potential adverse effects, recommending dosage management to minimize these risks; no new clinical results are reported.
1 citations
,
January 2013 in “Springer eBooks” Cosmeceuticals may benefit skin health but need more research for efficacy and safety confirmation.
August 2025 in “Journal of Pure and Applied Microbiology” This review discusses various therapeutic properties of bee venom, including its potential against cancer, infections, and inflammatory diseases, but notes limitations in clinical application due to variability and safety concerns, calling for further research.
20 citations
,
June 2022 in “Molecules” This review discusses three classes of thiazole-bearing compounds in drug development and presents preclinical findings but reports no new experimental results, highlighting the need for further drug discovery.
14 citations
,
January 2017 in “Elsevier eBooks” This review explores cannabigerol (CBG) as a potential therapeutic agent with various pharmacological activities but reports no new clinical results, emphasizing the need for further research on its efficacy and safety.
22 citations
,
June 2021 in “Plants” This study found that a methanolic extract of Sterculia foetida seeds demonstrated significant thrombolytic, anti-arthritic, analgesic, and antipyretic activities, with moderate cytotoxic effects in vitro and in vivo.
7 citations
,
June 2015 in “Cutaneous and Ocular Toxicology” This study attempts to classify histomorphologic reactions to drugs to aid in diagnosing drug eruptions, which are common in hospitalized patients but lack specific diagnostic features.
72 citations
,
December 2012 in “Expert Opinion on Drug Delivery” This review discusses niosomes' increasing popularity in dermatology for topical drug delivery due to their ability to enhance drug penetration, provide sustained release, and carry various drugs, while reporting no new clinical findings.
1 citations
,
March 2004 in “Military Medicine” This case report describes a 57-year-old male who developed bilateral ankle swelling and pain, potentially linked to a recent episode of fever and chills following prostatitis treatment.
46 citations
,
September 2014 in “Steroids” This review suggests that brassinosteroids may have similar biological activities in both plants and other organisms, prompting further exploration of steroid regulation mechanisms across different life forms.
61 citations
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September 2020 in “Bioactive Materials” This study found that the multifunctional FEA-PCEI dressing significantly accelerated wound healing, reduced scar formation, and promoted hair follicle neogenesis while providing antibacterial and anti-inflammatory benefits.
105 citations
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August 2010 in “Pharmacology & therapeutics” This article explores the potential of formyl-peptide receptor 2 agonists as innovative anti-inflammatory drugs, highlighting their ability to mimic the body's natural inflammation response, but it presents no new clinical findings.
2 citations
,
April 2023 in “Pharmacognosy Journal” This study found that bio fabricated herbal silver nanoparticles from Blumea lacera extracts demonstrated significant antibacterial activity against Staphylococcus aureus and Escherichia coli, and notable anti-inflammatory effects, though their antioxidant capacity was insignificant compared to the extract.
May 2019 in “Asian Journal of Pharmaceutical and Clinical Research” This study found that the ethyl acetate and chloroform fractions of Eclipta prostrata Linn. exhibited significant anti-inflammatory activity in a carrageenan-induced paw edema model and showed notable anti-arthritic potential in a formaldehyde-induced arthritis model.
January 1988 in “Chemical and Pharmaceutical Bulletin” This study found that ointments containing indomethacin and its calcium salt showed potent anti-inflammatory effects on rat paw edema and arthritis with minimal skin irritation, suggesting potential for clinical use.
February 2026 in “Frontiers in Materials” In this study, researchers developed iron-curcumin-coordinated nanoparticles to enhance curcumin's bioavailability and therapeutic effects, finding that these nanoparticles accelerate wound healing in diabetic mice by reducing inflammation and oxidative stress more effectively than free curcumin.
3 citations
,
January 2017 in “Revista chilena de nutrición” This review highlights that several clinical and epidemiological studies link a diet high in terpenoid compounds with a decreased risk of prostate cancer, supporting the potential use of terpenoids as therapeutic ingredients in treating this disease.
January 2025 in “Scripta Medica” This review suggests that natural compounds, particularly hydrolates, may improve burn wound healing and counter antibiotic resistance through their anti-inflammatory, antioxidant, and antimicrobial properties, offering promising complementary interventions.
July 2005 in “SKINmed/Skinmed” This study reported that BRL 7660 significantly reduced sebum secretion and acne symptoms in human studies with topical administration, but the placebo effect and commercial pressures halted further investigations.
10 citations
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March 2023 in “Journal of Chemistry” This study identified ten novel compounds that may effectively target steroid 5 alpha-reductase 2 (5αR-2) for potential treatment of benign prostate hyperplasia, exhibiting comparable binding energies to existing drugs like finasteride and dutasteride.
59 citations
,
June 2022 in “Frontiers in medicine” This review discusses the complex causes and treatment challenges of chronic inflammatory skin diseases, emphasizing the need for biomarkers to predict treatment responses; it reports no new clinical results.
9 citations
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April 2025 in “International Journal of Nanomedicine” This research highlights a hydrogel system that could significantly improve diabetic wound healing by releasing ibuprofen to both suppress inflammation and promote tissue regeneration, indicating a strong potential for future clinical use.
32 citations
,
January 2022 in “Oxidative Medicine and Cellular Longevity” This study found that cedrol, administered orally, exhibited potential antiarthritic effects in rats by reducing inflammation, oxidative stress, and arthritis severity.
20 citations
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December 2021 in “Plants” This review concludes that Tamarix aphylla, used traditionally for ailments such as tuberculosis and hepatitis, demonstrates various pharmacological activities, including antidiabetic and wound-healing effects, but stresses the need for further research to confirm its safety and effectiveness in humans.
15 citations
,
March 2021 in “Journal of clinical medicine” This review discusses common skin eruptions caused by biologics in treating inflammatory bowel disease and proposes tailored therapeutic approaches for managing these adverse reactions.
11 citations
,
August 1997 in “Expert Opinion on Therapeutic Patents” This review discusses nearly 70 patent applications for the treatment of androgenetic alopecia and other hair conditions, highlighting the mechanisms of action explored but reports no clinical results.
9 citations
,
May 2005 in “Expert Review of Clinical Immunology” This article examines anticytokine therapies for autoimmune diseases, highlighting the potential of anti-interferon-γ as a universal treatment for certain conditions and noting varying effectiveness of tumor necrosis factor-α inhibitors.
17 citations
,
January 2023 in “Frontiers in Pharmacology” This study found that 10,11-dibrominecrebanine (2Br-Cre) and Stephanine demonstrate significant anti-inflammatory and analgesic properties in various experimental models, with 2Br-Cre showing enhanced efficacy over Cre and both compounds potentially mediating their analgesic effects through opioid receptors.
7 citations
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May 2018 in “Indian Journal of Pharmacology” This study found that the methanolic extract of Carthamus caeruleus roots significantly reduced inflammation, promoted wound healing, and enhanced hair growth in experimental models, supporting its traditional use in Northern Algeria as a skincare remedy.