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In 2017, a new method was created to efficiently produce a topical antiandrogen, a compound used to treat excess sebum and acne, with a high yield and purity.

A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

Both estrogens and androgens are important for health in both males and females.

Hair loss, known as Androgenetic Alopecia, is often caused by hormones and can be diagnosed using noninvasive techniques. Treatments include topical minoxidil and oral finasteride, with new treatments being explored. There may also be a link between this type of hair loss and heart disease risk.

The study found key factors in the cause of hidradenitis suppurativa, its link to other diseases, and identified existing drugs that could potentially treat it.

The main prostate diseases in dogs are benign growth, infections, and cancer, with various treatments ranging from drugs to surgery, but cancer treatments have limited success.

Some cosmetic procedures show promise for treating hair loss, but more research is needed to confirm their safety and effectiveness.

Some common medications may harm male fertility by affecting hormones, sperm production, and sexual function.

PCOS management includes lifestyle changes and medications, with ongoing research into repurposed drugs for better treatment options.

The document concludes that Catalyst software is effective for drug design, identifying potent compounds for various medical conditions.

Finding new uses for existing drugs is promising and can lead to safer, more effective medicines.

Tumor suppressors help control inflammation in cancer and restoring their function could lead to new treatments.

Cyclodextrins improve how steroid drugs work and are used in marketed medications and environmental applications.

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

Menopause causes dry skin, wrinkles, and hair changes, with hormone therapy helping but not recommended just for these issues.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

A new compound, 3a, effectively fights prostate cancer better than finasteride.

New treatments for hair loss are being developed using molecular biology.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

Certain natural compounds called terpenes may help prevent prostate cancer.

Scientists made a chemical (compound 4e) that can be applied on skin to reduce oil production, which can help with acne, but it might cause skin sensitivity to light.

Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.

A compound made by Pfizer can potentially stimulate hair growth and reduce oil production, making it a good candidate for topical use.

Pfizer found that pantolactam-based compounds can reduce sebum (skin oil) production when applied topically.

New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.

Estrogens are key for bone growth spurts in both boys and girls and affect growth into adulthood.

High doses of testosterone disrupt hormone levels and receptor expression in the uterus, affecting fertility.

Five preservatives may disrupt hormone function and need more health and environmental risk assessment.