research An Open-Label Phase II Study of the Safety and Efficacy of Etanercept for the Therapy of Hidradenitis Suppurativa
Etanercept is safe and may help improve hidradenitis suppurativa, but more research is needed.
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research Genetic Alteration of Cyclic Adenosine 3',5'-Monophosphate-Dependent Protein Kinase Subunit Expression Affects Calcium Currents and Beta-Endorphin Release in AtT-20 Clonal Pituitary Cells
Changing protein kinase levels in pituitary cells affects calcium flow and beta-endorphin release.
research Treatment of Hair Loss
Finasteride and minoxidil are effective for hair loss, but continued research is needed for better treatments.
research Oligomeric Procyanidins in Apple Polyphenol Are Main Active Components for Inhibition of Pancreatic Lipase and Triglyceride Absorption
Apple polyphenol, especially oligomeric procyanidins, can reduce fat absorption and lower blood fat levels.
research Biology of Estrogens in Skin: Implications for Skin Aging
Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.
research Safety of Dermatologic Medications in Pregnancy and Lactation
Some skin medications are safe during pregnancy and breastfeeding, but others can harm the baby and should be avoided.
research Role of Cholesterol Sulfate in Epidermal Structure and Function: Lessons from X-Linked Ichthyosis
Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.
research Action of Topical Minoxidil in the Bald Stump-Tailed Macaque
Minoxidil promotes hair growth but stops working when discontinued.
research The Dark Art of Light Measurement: Accurate Radiometry for Low-Level Light Therapy
Most low-level light therapy studies did not accurately report how light was measured, affecting treatment reliability.
research Dose-Response Study of Topical Minoxidil in Male Pattern Baldness
Lowest effective minoxidil concentration is 1%, but 2% works better for male pattern baldness.
research Development of Search Strategies for Systematic Reviews: Validation Showed the Noninferiority of the Objective Approach
The objective approach for creating search strategies is as effective as the traditional method and might be better and more efficient.
research Hair Growth Induction: Roles of Growth Factors
EGF and FGF help hair growth by affecting cell differentiation and fiber growth.
research Long-Term Efficacy of Topical Minoxidil in Male Pattern Baldness
Topical minoxidil effectively treats male pattern baldness and prevents hair loss.
research Update on the Dermatologic Use of Systemic Glucocorticosteroids
Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.
research Refinement of Technique in Injection Lipolysis Based on Scientific Studies and Clinical Evaluation
Injection lipolysis effectively reduces small fat deposits and should be done with care and proper patient selection.
research Pseudopelade of Brocq: A Review of a Rare Hair Disorder Leading to Cicatricial Alopecia
Pseudopelade of Brocq is a unique hair loss condition, but its cause and development are still not fully understood.
research Quantitative Models for the Study of Hair Growth In Vivo
The conclusion is that small hair follicles cause baldness in macaques, and treatments like antiandrogens and minoxidil can prevent hair loss and promote regrowth.
research A Comparative Study of Minoxidil-Induced Myocardial Lesions in Beagle Dogs and Miniature Swine
A study found that minoxidil can damage the hearts of dogs and pigs, cautioning its use in humans.
research Inhibition of the Androgen Receptor by Antisense Oligonucleotides Regulates the Biological Activity of Androgens in SZ95 Sebocytes
Blocking the androgen receptor in skin cells reduces their growth response to male hormones, suggesting a possible treatment for skin conditions linked to androgens.
research Interaction of Chronic Ethanol Exposure and Finasteride: Sex and Strain Differences
Finasteride reduces alcohol withdrawal effects, especially in female mice.
research The CD44+ALDH+ Population of Human Keratinocytes Is Enriched for Epidermal Stem Cells with Long-Term Repopulating Ability
Certain human skin cells marked by CD44 and ALDH are rich in stem cells capable of long-term skin renewal.
research Genome-Wide Association Study of Skin Complex Diseases
Genetic variants linked to ten skin diseases were found, showing both immune and non-immune factors play a role.
research Sex-Specific Difference of Hippocampal Synaptic Plasticity in Response to Sex Neurosteroids
Sex neurosteroids cause different effects on hippocampal synaptic plasticity in males and females.
research Effect of Ultraviolet Radiation, Smoking, and Nutrition on Hair
Ultraviolet rays damage hair, smoking may cause hair loss, and good nutrition is important for hair health, but genetics mainly decide hair thickness.
research Candidate SNP Markers of Reproductive Potential Predicted by Significant Change in Affinity of TATA-Binding Protein for Human Gene Promoters
Certain genetic markers linked to reproductive potential were identified by their impact on a protein's ability to bind to genes.
research Dermatologic Signs and Symptoms of Substance Abuse
Substance abuse can cause various skin problems, including marks from injections, sores, premature aging, and increased cancer risk.
research Fetal Wound Healing Using a Genetically Modified Murine Model: The Contribution of P-Selectin
P-selectin is not the only factor that prevents scarring in fetal wound healing in mice.
research Types and Treatment of Hair Loss in Men and Women
The article concludes that different types of hair loss require specific treatments and psychological support is important.
research Effects of Oral Contraceptives on the Quality of Life of Women with Polycystic Ovary Syndrome: A Crossover Randomized Controlled Trial
Birth control pills containing cyproterone acetate improve the quality of life more for women with polycystic ovary syndrome after 6 months of use.
research Correction of Hair Shaft Defects Through Allele-Specific Silencing of Mutant Krt75
Using special RNA to target a mutant gene fixed hair problems in mice.