research Neurological Post-Acute Sequelae of SARS-CoV-2 Infection
Long COVID affects over half of COVID-19 survivors, causing a range of symptoms like fatigue and neurological issues, with no specific treatment yet.
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research Autoimmune Cicatricial Alopecia and the Role of Trichoscopy in Its Diagnosis: A Literature Review
Trichoscopy is essential for diagnosing and treating autoimmune cicatricial alopecia early.
research Rare Cutaneous Side Effects of Imiquimod: A Review on Its Mechanisms, Diagnosis, and Management
Imiquimod can cause rare skin side effects, some irreversible, and long-term follow-up is important for users.
research PC037: Vertical Root Fracture: Two Case Reports
Finasteride may cause gum side effects in some patients.
research Table of Contents
Understanding drug effects and careful monitoring are crucial for safe and effective dermatology treatments.
research New England Dermatological Society Meeting on October 1, 1961
Reassurance is important for postpartum hair shedding as it likely won't cause complete baldness.
research Queries and Minor Notes
Washing can prevent cancer from lubricating oils, extreme body temperatures need more study, Sulfomid is not recognized, no reliable diphtheria carrier treatment except surgery, eyelid injuries should heal before repair, heterophile antibody test is specific for mononucleosis, chlorine inhalations for colds are outdated, and wheat germ is safe.
research Challenges, Progress, and Prospects of Developing Therapies to Treat Autoimmune Diseases
More precise, personalized therapies are needed for autoimmune diseases.
research Crafting Polymeric and Peptidic Hydrogels for Improved Wound Healing
Advanced hydrogel systems with therapeutic agents could greatly improve acute and chronic wound treatment.
research Minoxidil: Right Atrial Cardiac Pathology in Animals and Humans
Minoxidil may cause heart issues in animals and humans.
research Multiplex matrix network analysis of protein complexes in the human TCR signalosome
The study applied a multiplex matrix system to analyze protein complexes in the T cell receptor (TCR) signalosome, focusing on samples from Jurkat cells and 7 alopecia areata patients compared to 5 controls. It identified distinct PiSCES biosignatures in alopecia areata patients, characterized by enhanced basal TCR signaling network activity and a potential imbalance between GADS and GRB2 activity. This imbalance might influence pathways related to cytoskeletal remodeling and integrin signaling. The study demonstrated that PiSCES analysis could effectively distinguish between disease and control conditions, providing insights into the underlying signaling pathways involved in alopecia areata. Despite limitations in detecting all protein interactions, the approach offered valuable insights into protein network activities and potential disease pathways.
research Melatonin-Loaded Nanocarriers: New Horizons for Therapeutic Applications
Melatonin-loaded nanocarriers improve melatonin delivery and effectiveness for various medical treatments.
research New Pharmaceutical Concepts for Sebaceous Gland Diseases: Implementing Today's Pre-Clinical Data into Tomorrow's Daily Clinical Practice
New treatments for skin conditions related to the sebaceous gland are being developed based on current research.
research Fox Fordyce Disease in a Prepubertal Girl
A 10-year-old girl with Fox Fordyce disease improved with treatment, suggesting the disease can occur before puberty and might be underdiagnosed in young girls.
research Drug-Induced Postinfantile Giant Cell Hepatitis
Certain liver diseases respond well to specific treatments and have varying risks for liver cancer.
research Amino Acids, Peptides, And Proteins In Cosmetic Science
The document concludes that cosmetics need biocompatible, eco-friendly ingredients due to aging populations and demand for effective products.
research Secondary Syphilis in HIV-Infected Men Who Have Sex with Men: A Case Report
HIV-infected men who have sex with men are at higher risk for aggressive syphilis, but treatment and tests are effective.
research Inconsolable Crying in Infants: Differential Diagnosis in the Pediatric Emergency Department
Most inconsolable crying in infants is not due to a serious cause, and a detailed check-up is typically enough to find the reason.
research Mast Cells and Scarring Alopecia: Is There a Clear Pathophysiological Relationship?
The document suggests a possible link between mast cells and scarring alopecia, recommending more research for potential treatments.
research Case 1: Severe Acne – Not Just Skin Deep
Severe acne in a young girl may indicate underlying hormonal issues.
research ZO-1 Boosts the In Vitro Self-Renewal of Pre-Haematopoietic Stem Cells from OCT4-Reprogrammed Human Hair Follicle Mesenchymal Stem Cells Through Cytoskeleton Remodeling
ZO-1 helps hair follicle stem cells renew better by changing their structure.
research Hereditary, Congenital, And Acquired Alopecias
Alopecia in animals can be hereditary, congenital, or acquired, with treatments and outcomes varying widely.
research Steroid Sulfatase: Molecular Biology, Regulation, and Inhibition
The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.
research Lichen Planopilaris and Frontal Fibrosing Alopecia as Model Epithelial Stem Cell Diseases
Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.
research Clinical and Histological Challenge in the Differential Diagnosis of Diffuse Alopecia: Female Androgenetic Alopecia, Telogen Effluvium, and Alopecia Areata – Part II
Diagnosing diffuse alopecia, a hair loss condition, can be challenging and may require a scalp biopsy or tracking the disease's progression when symptoms and skin tests aren't enough.
research Alopecia Areata: Pathogenesis, Genetic Factors, and Treatments Using Mouse Models
The document concludes that ongoing research using animal models is crucial for better understanding and treating Alopecia Areata.
research Geographic Tongue in Two Children with Nonpustular Psoriasis
Fox Fordyce disease might be more common in prepubertal girls than thought and can be managed with treatment.
research Phrynoderma and Acquired Acrodermatitis Enteropathica in Breastfeeding Women After Bariatric Surgery
Women who had bariatric surgery risk nutritional deficiencies causing skin issues during pregnancy and breastfeeding.
research The Hair Shaft: Normality, Abnormality, and Genetics
Hair microscopy is useful for diagnosing hair disorders, but clear definitions are needed for accurate genetic analysis.
research Cutaneous Reactions to Drugs
Skin reactions are a common reason for emergency visits due to drug allergies, with some severe cases needing intensive care.