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Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Finasteride affects frog testes by increasing testosterone, decreasing 5α-DHT, and impacting genes related to reproduction and other functions.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Menopause and aging can affect women's quality of life and sexuality, but hormone therapies may help alleviate these issues.

Routine thyroid tests for diffuse alopecia in women may not be necessary, but checking for iron deficiency anemia could be useful.

Aging scalp skin contributes to hair aging and loss, and more research is needed to develop better hair loss treatments.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

Spironolactone might help protect against severe lung problems in COVID-19 patients.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

Some hormone-related drugs may protect brain cells in Parkinson's disease differently in men and women.

Sex hormones affect brain injury differently in males and females.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

5-alpha reductase inhibitors may help protect the brain and gut in Parkinson's disease.

Mice without the enzyme HSD17B3 still produce normal testosterone, suggesting they have different ways to make it compared to humans.

DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.

Acne treatment with isotretinoin increases the presence of p53, a protein, in skin and oil glands, which may help reduce acne severity.

Environmental factors and chemicals might affect hormone balance and contribute to common hair loss.

The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.

Male hormones indirectly affect skin cell development by increasing growth factor levels from skin fibroblasts.

Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.

PFS and PSSD are similar conditions with persistent sexual dysfunction after stopping medication.

The review found no clear link between vitamin D receptor gene variations and polycystic ovary syndrome.

Finasteride blocks progesterone's effect on absence seizures in rats.

Testosterone reduces key molecules needed for early pregnancy in rats.

Females have higher estrogen receptor levels in hair than males, and these levels decrease in white hair compared to black hair.

Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.