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High androgen levels and genetic factors likely cause Becker's nevus and related symptoms.

The document talks about hard-to-treat and rare acne types, their connection with other health issues, the importance of correct diagnosis, and the challenges in managing them.

The document concludes that a systematic approach is crucial to identify causes of androgen excess in women beyond the most common cause, Polycystic ovary syndrome (PCOS).

Some women with PCOS have CYP21 mutations and IRS1 variants, but these genetic factors are not major contributors to PCOS.

An over-the-counter vitamin/mineral supplement improved hair loss and blood sugar control in a woman with non-classic 11-hydroxylase deficiency.

Some conditions mimic PCOS symptoms and need careful diagnosis to treat potentially serious health issues.

Insulin resistance contributes to hormone imbalances in many women with polycystic ovary syndrome.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Effective hirsutism management requires identifying the cause, combining new and traditional treatments, and setting realistic expectations for patients.

Hyperandrogenism increases heart disease risk in premenopausal women, but this risk is linked to obesity in postmenopausal women.

PCOS is a genetic disorder affecting women's reproductive health, with treatments focused on symptoms like insulin resistance and fertility.

Gene mutations can cause problems in male genital development.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Hormonal therapy is a treatment option for acne, the only medical treatment for hirsutism, and the most promising for androgenetic alopecia.

About 7% to 15% of Iranian women have polycystic ovary syndrome, depending on the criteria used to diagnose it.

Different types of polycystic ovary syndrome (PCOS) have varying severity, with Type I being the most severe and common.

PCOS is a complex condition that can lead to serious health issues, but early diagnosis and treatment can reduce these risks.

The document concludes that treatments for female hair loss and excess body hair are available, but managing expectations is important.

The guidelines help doctors diagnose and treat hormone-related disorders in women.

Female pattern hair loss is caused by multiple factors and while treatments like topical minoxidil, hormone therapy, and low-level light therapy can help, none can fully cure it.

Some women with PCOS have rare genetic variants linked to the condition.

Women with Polycystic Ovary Syndrome (PCOS) have lower levels of a substance called DIAPH1 in their blood, which is linked to changes in sugar metabolism and insulin resistance.

Losing 5-10% body weight can improve PCOS symptoms, letrozole is better than clomiphene for fertility, and managing weight and blood sugar is important to reduce pregnancy complications.

The N363S gene variant does not cause higher adrenal androgen levels in women with polycystic ovary syndrome.

Researchers found a new ABCD1 gene mutation linked to a rare brain and nerve disorder with unusual brain changes.

Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.

People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.

The document concludes that secondary syphilis cases are increasing and often misdiagnosed, pityriasis rubra pilaris can be distinguished from psoriasis by skin cell features, and different skin layers produce specific components during skin repair.

The guide recommends specific methods for diagnosing PCOS and various treatments for its symptoms, while considering the health impacts on adolescents.

Higher Lnk protein levels in ovaries may lead to insulin resistance in women with PCOS.