1 citations
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January 2016 in “Australasian Journal of Dermatology” This case study describes a 54-year-old man with an E600A mutation in the NOD-2 gene associated with Blau syndrome, who presented with skin involvement, differing from typical cases, and initially responded to colchicine treatment.
This study observed that nevus melanocytes do not exhibit signs of senescence, suggesting that their growth arrest is due to cell interactions and not directly caused by BRAF activation.
205 citations
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March 2012 in “Science Translational Medicine” PGD2 stops hair growth and is higher in bald men with AGA.
84 citations
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April 2015 in “Cosmetics” This review discusses various types of hair dyes, their mechanisms of action, molecular structures, application methods, and formulation aspects, but reports no new research findings.
78 citations
,
May 2012 in “Journal of Investigative Dermatology” A specific gene mutation causes woolly hair and hair loss.
36 citations
,
August 2022 in “Molecular Therapy — Nucleic Acids” This review discusses various gene therapy and non-viral delivery methods to promote angiogenesis for chronic wound healing, but it reports no new clinical results.
35 citations
,
April 2008 in “Journal of Biological Chemistry” This study found that the lack of expression and deletion of specific hair keratin genes on chromosome 7q36 in Hirosaki hairless rats suggests the crucial role of these genes in hair growth.
20 citations
,
August 2022 in “Archives of Medical Science” This publication discusses the 2021 ESC Guidelines for the prevention of cardiovascular disease in clinical practice and reports no new results.
18 citations
,
January 2018 in “BMC dermatology” This paper describes a case of epidermolysis bullosa simplex with muscular dystrophy associated with a novel PLEC mutation and diffuse alopecia, highlighting a potential genetic link that remains uncertain.
15 citations
,
September 2016 in “Hair transplant forum international” This abstract reviews the evolution of hair restoration techniques, from 19th-century surgical scalp flaps to modern FUE and FUT methods, without providing new clinical findings.
11 citations
,
January 2022 in “Journal der Deutschen Dermatologischen Gesellschaft” This review discusses current and emerging therapies for alopecia areata, highlights the challenges in managing this chronic disease, and emphasizes the importance of addressing its psychosocial impacts; it reports no new clinical results.
11 citations
,
September 2021 in “American Journal of Medical Genetics Part A” This study reports that newly diagnosed patients with Bachmann-Bupp syndrome exhibit a broader phenotype than previously documented, including late-onset seizures, and suggests a possible universal biochemical mechanism involving elevated ODC activity.
11 citations
,
January 2018 in “IET Nanobiotechnology” In this study, poly (ɛ-caprolactone)–chitosan–poly (vinyl alcohol) nanofibrous scaffolds used on canine skin wound models were found to significantly accelerate healing rates of excision and burn wounds, without inducing immunogenic reactions.
10 citations
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November 2023 in “Frontiers in Pharmacology” In this study, researchers developed a self-assembling hydrogel called RADA-PDGF2 and found it to accelerate wound closure in a mouse model due to its pro-proliferative and pro-migratory properties, without causing cytotoxicity or immunogenicity.
7 citations
,
August 2022 in “Journal of Nanobiotechnology” This review discusses recent advances in stimuli-responsive nanoformulations for CRISPR-Cas9 delivery, highlighting their design rationales and potential biomedical applications, but reports no new experimental results.
7 citations
,
October 2011 in “BMC Cancer” This study found no evidence that HDGF expression transforms melanocytes into tumors in a mouse model, although it may play a role in cell differentiation and tumor progression.
6 citations
,
March 2015 in “European Journal of Public Health” This study suggests that long-term use of hair dyes may be associated with higher testosterone levels among premenopausal Japanese women.
5 citations
,
September 2021 in “Clinical case reports” This case report documents the first known instance of Graham‐Little Piccardi Lassueur Syndrome in Saudi Arabia, observed in an adult dark-skinned male.
4 citations
,
March 2023 in “Journal of medical case reports” The authors concluded that coagulopathy can result from vitamin E supplementation, even at marginally elevated levels, especially when combined with other drugs that increase bleeding risk.
3 citations
,
June 2023 in “Medicines” This review identified alopecia as a significant cosmetic side effect of antiseizure medications, particularly with valproate, lamotrigine, and carbamazepine, noting that hair loss often improves after dose adjustment.
3 citations
,
September 2016 in “Hair transplant forum international” This abstract outlines the clinical onset of androgenetic alopecia as the most common cause of male pattern baldness but reports no further results.
1 citations
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September 2024 in “Animals” In this study, researchers identified six unique genetic variants of a sheep gene, KRTAP19-3, with specific variants linked to changes in wool fibre traits, such as increased fibre diameter variability, suggesting these genetic differences affect wool characteristics in Chinese Tan sheep.
1 citations
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January 2025 in “Proceedings of the National Academy of Sciences” This study used cryoelectron microscopy to unveil the structure of LPA-bound human LPAR6, revealing unique ligand binding and recognition modes distinct from LPAR1, which may aid in designing targeted compounds for hair loss and cancer.
August 2026 in “Journal of Cosmetic Dermatology” This systematic review reported that both hair transplantation and topical minoxidil were associated with cosmetic improvement in patients with temporal triangular alopecia, but noted that the evidence is based on low-level studies and highlighted the need for higher-quality research, especially in pediatric populations.
January 2026 in “British Journal of Health Psychology” This review highlights the significant impact of alopecia on personal identity and social interactions, emphasizing the need for personalized, non-pharmacological interventions and improved collaboration in healthcare training to better support those with appearance-altering conditions.
March 2025 in “International Journal of Molecular Sciences” This review explores melatonin's role in hair follicle cycles and its molecular mechanisms that enhance antioxidant capacity and modulate gene expression, offering potential strategies to improve cashmere production and treating human alopecia, according to the authors.
March 2025 in “Cosmetics” This study found that combining PRP with topical minoxidil or finasteride significantly improved hair density and thickness, with patient satisfaction highest for multiple treatment combinations and longer durations.
July 2023 in “IntechOpen eBooks” Some types of hair loss can be reversed, others are permanent, and treatments vary by type.
July 2023 in “Journal of Cosmetic Dermatology” This study investigated AGA professionals' perspectives and found that 42% were misled by commercial influences, underestimated these biases' extent, and faced ethical challenges in treatment due to societal pressures and misinformation, highlighting a need for evidence-based guidance and research scrutiny tools.
July 2023 in “Developmental medicine and child neurology/Developmental medicine & child neurology” This study found that patients with Bachmann-Bupp syndrome treated with DFMO showed improvements in hair growth, muscle tone, and development.