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Valproate is a mood stabilizer for bipolar disorder but has side effects and risks, especially during pregnancy.

Scientists made a chemical (compound 4e) that can be applied on skin to reduce oil production, which can help with acne, but it might cause skin sensitivity to light.

Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.

Compound 15a was effective in inhibiting 5α-reductase.

Mexican patients had a lower incidence of skin reactions to drugs and no significant link between these reactions and the TNF2 gene variant.

Some off-label treatments increase hair density, but long-term safety unknown.

New drug delivery systems improve treatment effectiveness and patient experience.

The document concludes that individualized treatment for malignant epithelial tumors is necessary and more research on metastatic squamous cell carcinoma treatments is needed.

Pfizer found that pantolactam-based compounds can reduce sebum (skin oil) production when applied topically.

The combination therapy improved skin pigmentation.

A new, less toxic and more efficient method to create the anti-baldness compound RU58841 was developed in 2014.

The right dosage of CPA and TB can work as a safe and reversible male contraceptive in monkeys.

Germacrene analogs, especially 8-Hydroxy germacrene B, are more effective than germacrone at blocking a hormone-related enzyme and could help treat hair loss.

Sex hormones might influence bladder cancer development, and aromatase inhibitors could increase risk in postmenopausal women.

Female pattern hair loss affects 32.3% of women, increasing with age and showing no racial differences.

Taking Saw palmetto and Pygeum africana can change the levels of certain steroids in urine, which could cause confusion in doping tests.

Cernitin™, a pollen extract, was found to significantly reduce pain and inflammation in rats with chronic prostatitis, suggesting it could be a useful alternative to certain anti-inflammatory drugs.

Formononetin, found in red clover, may treat hair loss with fewer side effects.

SM04554 may increase hair growth as a topical treatment for androgenetic alopecia.

Fever and rash can be early signs of lupus.

The research shows how certain drug molecules form stable structures with polymers, which could help create new drug forms.

Scalp needle mesotherapy can effectively treat hair loss and improve hair growth.

Platelet-rich plasma is a promising and cost-effective treatment for hair and skin issues in older adults in India.

PRP is a versatile and affordable treatment for improving appearance in the elderly, with patient needs and expectations being important.

A 44-year-old woman with Down's syndrome was diagnosed with both rheumatoid and gouty arthritis and treated with multiple medications.

Removing a testicular tumor in a dog reduced its aggressive behavior and skin problems.

Adiantum capillus extract reduces pain and swelling in animals.

The document concludes that various topical treatments show promise for skin conditions like atopic dermatitis, psoriasis, and hair loss.

SM04755 may be an effective topical treatment for psoriasis.

Fisetin may help treat psoriasis and reduce skin inflammation.