Search

everythinglearnresearchcommunity

for

Search:↓

Scientists created iodinated arylhydantoins and arylthiohydantoins that could potentially be used for imaging prostate cancer. Some versions with specific side-chains showed high potential for this use.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Scientists at the University of Michigan Medical School successfully created a special compound that can be used to improve imaging of prostate cancer.

Three compounds were found to inhibit a prostate disease-related enzyme and reduce prostate size more effectively than the current treatment, suggesting they could be used for treating benign prostatic hyperplasia.

Diagnosing hyperandrogenism in women is complex and requires accurate testing methods and consideration of SHBG levels.

DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.

SHBG binding properties are unchanged in male liver cirrhosis patients.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

Certain Dibenzo derivatives may help treat prostate cancer.

Researchers created a model to understand heart aging, highlighting the role of microRNAs and identifying key genes and pathways involved.

The X5 Hairlaser might help treat male hair loss, but more research is needed.

Researchers created a model to understand heart aging, highlighting key genes and pathways, and suggesting miR-208a as a potential heart attack biomarker.

Enobosarm significantly increased muscle mass and improved physical function in elderly men and postmenopausal women without serious side effects.

Sex hormones may influence COVID-19 severity, with males at higher risk, and certain hormone therapies could potentially treat the virus.

Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.

New compounds were made that block an enzyme linked to breast cancer better than existing treatments.

Current treatments for Alopecia Areata have mixed success, and there's a need for better, more accessible options and support for affected individuals.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

A new method accurately measures steroid hormones in a few hair strands and could help study chronic stress and hair loss.

Cocaine impairs male sexual behavior and alters testosterone metabolism in the brain.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

Men and women have different levels and production of brain steroids, which may affect their risk for certain brain disorders.

The Androgen Receptor could be a target for treating diseases like cancer, but more research is needed to confirm the effectiveness of potential treatments.

17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.

The conclusion is that endocrinology significantly impacts medicine with various common medications used for treatment.

Vitamin D receptor binds similarly to natural and synthetic ligands, affecting gene regulation.

The vitamin D receptor can work without its usual activating molecule.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

The nature of the side chain in RU 58841 derivatives greatly affects its AR affinity, with the N-(iodopropenyl) derivative 13 showing the highest AR binding affinity, suggesting its potential for developing high-affinity radioiodinated AR radioligands.