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Exemestane may protect bones by stimulating osteoblast growth through androgen-related pathways.

Fulvestrant is a well-tolerated new treatment for advanced breast cancer that may delay chemotherapy.

Non-hormonal treatments should be used first for sexual dysfunction in postmenopausal breast cancer patients on aromatase inhibitors, with hormones as a second option.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Sex hormones might influence bladder cancer development, and aromatase inhibitors could increase risk in postmenopausal women.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Testosterone helps human pancreatic cells increase insulin release.

Exemestane is effective and safe for treating certain breast cancers, with mild side effects, but needs more research on long-term effects.

The document explains how certain drugs block hormones to treat cancers like breast and prostate cancer.

CDK4/6 inhibitors have improved treatment outcomes for certain advanced breast cancer patients.

Exposure to certain sex hormones can increase health risks, while some hormone therapies may offer benefits for specific conditions.

Letrozole reduces seizures but not brain damage in mice.

Patients with HR+/HER2- advanced breast cancer commonly experience fatigue, hair loss, and pain, which significantly affect daily activities.

There are many ways to treat Polycystic Ovary Syndrome, including lifestyle changes, surgery, and various medications, but more research is needed for better treatments.

New treatments for PCOS focus on insulin resistance and reducing testosterone levels, along with traditional hormone therapies.

Nandrolone and oxandrolone could help treat male health issues like muscle loss and low testosterone.

Estrogens are key for bone growth spurts in both boys and girls and affect growth into adulthood.

Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

Anticancer drugs are increasingly found in surface waters, and their long-term environmental effects are not well understood, requiring better testing methods.

5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.

Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.

Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

New treatments for male hypogonadism are effective and should be personalized.

Estrogen therapy can reduce skin aging but has cancer risks.

Honokiol might help reduce male skin aging by maintaining testosterone levels.

Stinging nettle has compounds that help with joint pain, arthritis, and prostate issues.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.