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The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

Blocking CRF1 receptors improved male hormone levels and reduced testicular tumor size in men with a specific adrenal condition.

PPAR-γ is important for healthy hair and its problems, and more research on PPAR-γ treatments is needed.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Over 50% of women over 50 experience hair loss, with minoxidil being the only proven effective treatment.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Cyproterone acetate is the preferred treatment for women's hyperandrogenism when estrogen/progestogen use is safe.

Nutraceuticals that promote hair growth do not reduce tamoxifen's effectiveness in breast cancer treatment.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

Using finasteride or dutasteride may cause long-lasting erectile dysfunction.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Some treatments work for common baldness, but there's less evidence for other hair loss types, and more research is needed.

Hormone therapy affects hair growth in transgender individuals, with testosterone potentially causing hair loss in trans men and estrogen reducing facial/body hair in trans women; treatment options vary.

DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.

Spironolactone can cause side effects like high potassium levels and breast enlargement, and patients need careful monitoring.

Exposure to certain sex hormones can increase health risks, while some hormone therapies may offer benefits for specific conditions.

The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.

Men and women react differently to opioids, with hormones potentially influencing these differences.

5α-reductase inhibitors don't stop bladder cancer from developing or getting worse.

For women with moderate to severe unwanted hair growth or acne, birth control pills are the first choice, with other medications like cyproterone, spironolactone, flutamide, or finasteride as alternatives, and permanent hair removal should be done with electrolysis or laser.

Birth control pills help treat skin and hair growth problems linked to high male hormone levels.

Menopause can cause skin issues, and seeing a dermatologist helps.

A new compound that could treat various androgen-related conditions was created and analyzed.

The compound was successfully made and shows potential for treating prostate cancer.

Testosterone replacement therapy helps manage deficiency and has various methods, but requires careful monitoring to avoid side effects.

We need better ways to test and understand SARMs to make safer and more effective treatments.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

Testosterone is crucial for development, growth, and various body functions in mammals.