75 citations,
September 2015 in “Acta biomaterialia” Alkylation of human hair keratin allows for adjustable drug release rates in hydrogels for medical use.
153 citations,
June 2015 in “GenomeBiology.com” The environment around the time of conception can change the VTRNA2-1 gene in a way that lasts for years and may affect disease risk.
[object Object] 81 citations,
February 2016 in “Veterinary pathology” Progeroid mouse models show signs of early aging similar to humans, helping us understand aging better.
12 citations,
November 2022 in “Toxics” EtG in hair can help detect alcohol use but may be inaccurate in people with certain health conditions.
11 citations,
January 2020 in “Medical Journal Armed Forces India” Insulin resistance is a complex condition that can lead to many diseases and has few treatment options.
5 citations,
December 2022 in “Toxins” Neurotoxins can affect neurotransmitter release and have potential in treating muscle, pain, and cancer conditions, but more research is needed on how they work.
1 citations,
March 2023 in “Frontiers in Cardiovascular Medicine” A specific gene variant is linked to heart disease, increased heart muscle, curly hair, and thick skin on palms and soles.
1 citations,
June 2022 in “Pharmaceutics” Minoxidil's absorption is too variable for it to be a reliable reference drug.
1 citations,
January 2021 in “Acta Cirurgica Brasileira” Dutasteride and finasteride cause kidney damage, with dutasteride being more harmful.
Peptide hydrogels show promise for healing skin, bone, and nerves but need improvement in stability and compatibility.
February 2009 in “Mayo Clinic proceedings” A woman's new seizures were caused by a brain tumor likely linked to her past cancer treatment, and choosing safe seizure medications is important for women who can have children.
479 citations,
June 2014 in “Science” Epithelial stem cells can adapt and help in tissue repair and regeneration.
112 citations,
August 2012 in “The American Journal of Human Genetics” Mutations in the RBPJ gene cause Adams-Oliver Syndrome.
81 citations,
September 2009 in “Birth defects research” Different body areas in mice produce different hair types due to interactions between skin layers.
65 citations,
September 2014 in “BMC genomics” Different hair types in mammals are linked to variations in specific protein genes, with changes influenced by their living environments.
57 citations,
April 2009 in “Differentiation” SDF-1/CXCL12 and its receptor CXCR4 are crucial for melanocyte movement in mouse hair follicles.
36 citations,
January 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” The document concludes that understanding genetic mutations in the PI3K-AKT-mTOR pathway can lead to better diagnosis and treatment for certain genetic skin disorders.
22 citations,
March 2021 in “Materials Today Bio” Scaffold-based strategies show promise for regenerating hair follicles and teeth but need more research for clinical use.
19 citations,
December 2021 in “Endocrine Reviews” There are various effective hormone treatments for puberty induction in boys and girls with hypogonadism, and starting treatment early is important.
[object Object] 18 citations,
January 2016 in “Journal of Clinical Medicine Research” A woman with lupus and severe nerve damage improved with specific treatments.
13 citations,
October 2021 in “Anais Brasileiros de Dermatologia” Dermoscopy is effective for diagnosing various skin infestations and infections.
12 citations,
January 2003 in “Dermatology Online Journal” A new treatment for hair loss was tested and most participants saw their hair loss stop within 2-8 weeks, with up to 50% more hair after 4 months, and no side effects.
11 citations,
February 2018 in “Medical science monitor” An alternating inflatable head pad reduced pressure ulcers and hair loss in heart surgery patients.
10 citations,
November 2021 in “International journal of molecular sciences” Sheep and goat hair fibers are complex due to keratin-associated proteins, which are important for fiber properties and growth.
7 citations,
May 2021 in “General and comparative endocrinology” Muskoxen's qiviut cortisol levels indicate their stress hormone activity over the hair growth period.
6 citations,
December 2022 in “International Journal of Molecular Sciences” Hormone imbalance is linked to Hidradenitis Suppurativa, a skin condition, and treatments like anti-androgenic therapy and metformin can help. It's also suggested to check patients for insulin resistance and Polycystic Ovary Syndrome.
5 citations,
January 2018 in “International Journal of Trichology” Hair strength is similar across different scalp areas, and not affected by age, gender, or hair thickness.
4 citations,
February 2023 in “Frontiers in Oncology” Nano-Pulse Stimulation™ Therapy is more effective and less damaging than cryoablation for treating melanoma tumors in mice.
4 citations,
January 2023 in “Andrology” The testes produce sperm and hormones essential for male development.
4 citations,
September 2010 in “Journal of Medical Case Reports” A man developed autoimmune issues after a transplant, improved with treatment, but died from leukemia relapse.