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570-600 / 1000+ resultsresearch Teratogenic effect of isotretinoin in both fertile females and males (Review)
Isotretinoin can cause serious birth defects and needs careful use, especially in pregnant women.
![Psychosocial impact of cicatricial alopecias](/images/research/36d5c575-2e52-49a5-b257-0143c720e36d/small/26214.jpg)
research Psychosocial impact of cicatricial alopecias
Most patients with cicatricial alopecias face significant psychological and social challenges due to their hair loss.
![Hair follicle-derived mesenchymal stem cells decrease alopecia areata mouse hair loss and reduce inflammation around the hair follicle](/images/research/eff0d3b8-aba7-4a72-8f9a-2474cec7db56/small/17098.jpg)
research Hair follicle-derived mesenchymal stem cells decrease alopecia areata mouse hair loss and reduce inflammation around the hair follicle
Hair follicle stem cells reduced hair loss and inflammation in mice with a condition similar to human alopecia.
![Secreted Frizzled-related protein 4 inhibits the regeneration of hair follicles](/images/research/426bc8b7-95dc-420e-b3f2-0842cfc33813/small/19375.jpg)
research Secreted Frizzled-related protein 4 inhibits the regeneration of hair follicles
A protein called sFRP4 can slow down hair regrowth.
![Hair Growth Promoting Effects of 650 nm Red Light Stimulation on Human Hair Follicles and Study of Its Mechanisms via RNA Sequencing Transcriptome Analysis](/images/research/8f5350a5-ae4c-497f-a0eb-02049a267190/small/17320.jpg)
research Hair Growth Promoting Effects of 650 nm Red Light Stimulation on Human Hair Follicles and Study of Its Mechanisms via RNA Sequencing Transcriptome Analysis
650 nm red light helps hair grow and prevents hair loss by affecting certain genes and biological processes.
research Advances in molecular pathogenesis of hidradenitis suppurativa: Dysregulated keratins and ECM signaling
Recent findings suggest that genetic factors, immune system issues, and skin cell defects might contribute to the development of hidradenitis suppurativa.
![Trace element zinc and skin disorders](/images/research/8463c66c-6e99-4744-a036-b13c47bbfe16/small/23609.jpg)
research Trace element zinc and skin disorders
Zinc is important for skin health, and supplements can help treat various skin and hair disorders, but more research is needed for conditions like psoriasis and vitiligo.
![AIRE Deficiency Leads to the Development of Alopecia Areata‒Like Lesions in Mice](/images/research/2a8fb76f-7a5e-4275-9ac4-e3c2f93353d0/small/36929.jpg)
research AIRE Deficiency Leads to the Development of Alopecia Areata‒Like Lesions in Mice
AIRE deficiency causes hair loss similar to alopecia areata in mice.
research Genomic and Transcriptomic Characterization of Atypical Recurrent Flank Alopecia in the Cesky Fousek
The study found that the hair loss condition in Cesky Fousek dogs is influenced by multiple genes affecting skin and muscle structure, fat metabolism, and immunity.
![Apoptosis in Hair and Skin: A Review](/images/research/8ecd20b9-a26f-43df-a862-3de6ad20e3c8/small/17627.jpg)
research Apoptosis in Hair and Skin: A Review
The study concludes that regulating apoptosis could lead to new treatments for various skin and hair conditions.
![Clinical and Genetic Aspects of Alopecia Areata: A Cutting Edge Review](/images/research/f3c55fe5-5417-47bf-a810-fe3601a500d0/small/16571.jpg)
research Clinical and Genetic Aspects of Alopecia Areata: A Cutting Edge Review
Hair loss from Alopecia Areata is caused by both genes and environment, with several treatments available but challenges in cost and relapse remain.
research Alopecia areata
Alopecia areata is an autoimmune disease with genetic links, treatable with certain medications, and can affect mental health.
![Deciphering the molecular mechanisms of stem cell dynamics in hair follicle regeneration](/images/research/1cabbfbb-0d7c-4240-83a4-7eb51f62be13/small/26288.jpg)
research Deciphering the molecular mechanisms of stem cell dynamics in hair follicle regeneration
Different stem cells are key for hair growth and health, and understanding their regulation could help treat hair loss.
![Recent Advances in Understanding of the Etiopathogenesis, Diagnosis, and Management of Hair Loss Diseases](/images/research/735bc27d-e949-4e23-9d9a-2031096287f7/small/15659.jpg)
research Recent Advances in Understanding of the Etiopathogenesis, Diagnosis, and Management of Hair Loss Diseases
New understanding and treatments for hair loss are improving, but more research is needed.
![Which is the ideal JAK inhibitor for alopecia areata – Baricitinib, tofacitinib, ritlecitinib or ifidancitinib - Revisiting the immunomechanisms of the JAK pathway](/images/research/9a3f918e-dc7e-4193-8e5a-35e4529e0593/small/23333.jpg)
research Which is the ideal JAK inhibitor for alopecia areata – Baricitinib, tofacitinib, ritlecitinib or ifidancitinib - Revisiting the immunomechanisms of the JAK pathway
No single ideal JAK inhibitor for alopecia areata has been determined; JAK3 inhibitors may be promising with fewer side effects.
research Hair follicle–derived IL-7 and IL-15 mediate skin-resident memory T cell homeostasis and lymphoma
Hair follicle-derived IL-7 and IL-15 are crucial for maintaining skin-resident memory T cells and could be targeted for treating skin diseases and lymphoma.
research Seaweeds as Source of Bioactive Substances and Skin Care Therapy—Cosmeceuticals, Algotheraphy, and Thalassotherapy
Seaweeds have beneficial compounds for skin care, including anti-aging and protective effects.
research Impaired Notch‐MKP ‐1 signalling in hidradenitis suppurativa: an approach to pathogenesis by evidence from translational biology
Faulty Notch signalling may cause hair follicle changes and inflammation in hidradenitis suppurativa.
research Overview of Alopecia Areata
Alopecia areata is a genetic and immune-related hair loss condition that is often associated with other autoimmune diseases and does not typically cause permanent damage to hair follicles.
research Low‐fluence Q‐switched Nd: YAG 1064‐nm laser and intense pulsed light for the treatment of melasma
Combining LFQS and IPL is more effective and faster for treating melasma than LFQS alone.
research Resident Memory T Cells in Autoimmune Skin Diseases
Certain immune cells contribute to skin autoimmune diseases, and some treatments can reverse hair loss in these conditions.
![Pathomechanisms of immune-mediated alopecia](/images/research/367ad4ea-2c9f-4d0a-a692-230e30eb57db/small/17678.jpg)
research Pathomechanisms of immune-mediated alopecia
The study concluded that immune cells attacking hair follicles cause hair loss in alopecia, with genetics and environment also playing a role, and highlighted the potential of certain treatments.
research Topical immunotherapy of severe alopecia areata with diphenylcyclopropenone (DPCP): experience in an Iranian population
DPCP is effective for treating severe alopecia areata, but relapse is common.
research Alopecia Areata: An Autoimmune Disease of Multiple Players
Alopecia areata is an incurable autoimmune condition causing hair loss, with research aiming for better treatments.
research Medium-dose prednisolone pulse therapy in alopecia areata
Medium-dose prednisolone pulse therapy is effective and safe for multifocal alopecia areata but not for more severe forms.
research Lifestyle Factors Involved in the Pathogenesis of Alopecia Areata
Certain daily habits like stress, diet, and sleep can affect the severity of hair loss in alopecia areata.
![Skin ‑ a vast organ with immunological function (Review)](/images/research/ef816219-bf5b-499d-b877-f63deca35b4d/small/19299.jpg)
research Skin ‑ a vast organ with immunological function (Review)
The skin is a large organ that plays a role in the immune system.
![Lichen planopilaris and frontal fibrosing alopecia: review and update of diagnostic and therapeutic features](/images/research/3c5b9f59-8575-44c2-a614-df90826cec0e/small/26849.jpg)
research Lichen planopilaris and frontal fibrosing alopecia: review and update of diagnostic and therapeutic features
The document concludes that more research is needed to find effective treatments for Lichen planopilaris and Frontal fibrosing alopecia.
![Perspectives on miRNAs Targeting DKK1 for Developing Hair Regeneration Therapy](/images/research/6a017771-677b-460e-a7f5-737c2b526523/small/17091.jpg)
research Perspectives on miRNAs Targeting DKK1 for Developing Hair Regeneration Therapy
Targeting a protein that blocks hair growth with microRNAs could lead to new hair loss treatments, but more research is needed.