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The G60S Connexin43 mutation causes hair growth issues and poor hair quality in mice, similar to human ODDD patients.

The gene SDR5A1 is found in scalp hair of both hirsute and normal individuals, but it does not explain differences in hair growth.

Chemotherapy can cause significant hair thinning and changes in hair texture, while tamoxifen has a smaller effect.

Testosterone conversion to 5α-DHT may not be essential for its effects on the skin.

Different types of scarring alopecia may be stages of one disease, and accurate diagnosis is crucial to prevent permanent hair loss.

The enzyme type 1 5α-reductase is more active in the hair follicle's lower part than in the skin's outer layer.

Skin changes can indicate hormonal imbalances and help diagnose endocrine disorders.

Certain sex hormones and antiandrogens can either slow down or speed up the growth of human hair follicle cells depending on their concentration.

New hair loss treatments may include topical medications, injections, and improved transplant methods.

A gene deletion in mice causes weak protein, immune issues, hair loss, airway problems, and wasting disease.

Androgens can cause hair growth in some areas but hair loss on the scalp.

Scalp cooling to prevent hair loss from chemotherapy works for some but not all, and studying hair damage markers could improve prevention and treatment.

Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.

Using polymeric micelles to deliver spironolactone topically could improve wound healing in skin affected by glucocorticoids.

The study concluded that both estrogen and androgen receptors, which decrease with age, are linked to skin aging and may be hormonally regulated.

The document concludes that the human keratin gene cluster is complex, with a need for updated naming to reflect over 50 functional genes important for hair and skin biology.

Hair loss has many causes and treatments, and losing some hair daily is normal; proper diagnosis is key, and minoxidil can help treat it.

Male pattern baldness may be caused by factors like poor blood circulation, scalp tension, stress, and hormonal imbalances, but the exact causes are still unclear.

Rat skin takes up and processes testosterone differently than other organs, with testosterone being more important for the skin than its metabolite 5α-DHT.

Topical therapies show promise for hair loss and acne treatment with minimal side effects.

The document concludes that various childhood hair and nail disorders exist, some may improve on their own, and advances in genetics and immunology could enhance treatment and counseling.

New acne treatments include combination creams, advanced retinoids, and light therapies, focusing on safety and patient adherence.

Male yak hair growth is influenced by DHT synthesis, which is promoted by 5α-red1 and AR during growth phases, while E2 may inhibit growth through ERα.

Stress, nutritional issues, and chronic diseases can cause hair loss, and nail changes may signal internal diseases; treatment focuses on the underlying cause.

Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.

Steroid hormones are crucial for body functions and have various medical uses, but their misuse can lead to dependence.

Androgens play a key role in hair growth and disorders like baldness and excessive hairiness.

Telogen effluvium is a hair loss condition caused by various factors and requires a thorough examination to diagnose and differentiate from other hair loss types.

Kir6.1 mutations in Cantú syndrome increase channel sensitivity and hyperpolarization, while SUR2B mutations do not.

The document concludes that scalp cooling and treatments like minoxidil can help manage hair loss from cancer therapy.