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Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.

The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.

Researchers found two new genetic variants linked to Alzheimer's disease.

Doctors should recognize and treat PCOS early in primary care to manage symptoms and lower risk of other health issues.

There is no significant link between alopecia areata and the PON1 enzyme polymorphisms studied.

Hirsutism is excessive hair growth in women often caused by polycystic ovarian syndrome, and identifying the cause is important for managing associated health risks.

Cyproterone acetate is effective for treating hirsutism and acne but less so for hair loss, with side effects similar to birth control pills.

Using steroids can increase the risk of heart problems.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

Women with congenital adrenal hyperplasia (CAH) have more sexual function issues than those with polycystic ovary syndrome (PCOS), but physical activity can improve sexual functioning in all women.

The document suggests more research is needed to understand the link between baldness and prostate cancer.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Wnt signaling is crucial for skin wound healing and reducing scars.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

Insulin resistance is significantly linked to a higher risk of depression in women with PCOS.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

Vitamin D and estrogen may help protect heart and kidney health, and maintaining sufficient vitamin D levels could be especially beneficial for African Americans, postmenopausal women, and people with chronic kidney disease.

Transdermal testosterone can improve sexual desire in postmenopausal women but lacks long-term safety data and is not FDA-approved for this use.

Many adult women suffer from persistent or late-onset acne, and while various treatments exist, finding the right one can be challenging.

A woman's mature cystic teratoma caused her virilization by producing testosterone.

400 nm particles penetrate hair follicles best, but mouse models aren't fully reliable for human studies.

Keratinocytes and adipose-derived stem cells can effectively heal difficult skin wounds.

Severe hair loss (androgenetic alopecia) is linked to higher risk of heart disease (cardiovascular atherosclerosis).

Baricitinib effectively and safely improves hair growth in patients with severe alopecia areata.

Androgenetic alopecia in men is genetic and linked to health issues like obesity and heart disease, with treatments including minoxidil, finasteride, and hair transplants.

Many women with PCOS in Saudi Arabia suffer from depression and anxiety.

Baricitinib improved severe hair loss in adults over 52 weeks and was safe to use.

Women with PCOS have a higher chance of experiencing depression, anxiety, and sleep disorders.

Lysophospholipids like LPA and S1P are important for hair growth, immune responses, and vascular development, and could be targeted for treating diseases.

Menopause can cause hair thinning and texture changes due to hormonal and metabolic shifts.