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Menopause significantly reduces skin collagen, leading to thinner, less elastic skin, and hormone replacement may help but requires careful consideration.

Testosterone replacement may improve sexual desire and bone health in women with low androgen levels, but more research is needed on its long-term safety.

Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Certain gene variants in estrogen receptors are linked to polycystic ovary syndrome, mainly affecting metabolism, in Tunisian women.

Most dogs with alopecia had higher than normal levels of certain hormones, but hair loss might not always be linked to these hormone changes.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

Obese women had more testosterone and less acne, but similar hair growth compared to non-obese women.

Two women with very high androgen levels had only slight skin issues, one due to a non-classical adrenal disorder and the other due to an adrenal tumor.

Testosterone therapy can improve sexual satisfaction and mood in surgically menopausal women when used with estrogen, but its long-term safety and effects on naturally menopausal and premenopausal women are unclear.

Neuroimaging suggests that treatments targeting brain steroids could help control epilepsy, especially types linked to the menstrual cycle.

Postmenopausal ovary stromal cells have a unique makeup and limited steroid production, suggesting androgens come from the adrenal gland.

GnRH analogues are effective for diagnosing and treating female androgen excess, offering a non-surgical option.

Oral contraceptives may cause hair loss in women.

Advancements in male reproductive medicine are ongoing, but more research and improved treatments are needed in several areas.

A transwoman developed a brain tumor after nine years of hormone therapy, suggesting a possible link between the treatment and tumor development.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Testosterone may slow down wound healing and increase inflammation.

Menopause and aging can affect women's quality of life and sexuality, but hormone therapies may help alleviate these issues.

The conclusion is that accurately identifying the cause of high androgen levels in women with PCOS is crucial and requires specific tests.

In Japan, sex reassignment surgery for gender identity disorder faces challenges and needs better medical support and education.

Gut microbes significantly affect brain steroid levels.

Diet changes hormone levels in pregnant ewes by affecting metabolism, not placental synthesis.

Men with frontal male pattern baldness may have a higher risk of gastric cancer.

Triptorelin helps evaluate hormone production in Sertoli-Leydig cell tumors.

Long-term use of finasteride in women can cause hormonal changes, DNA damage, and menstrual issues.

Acne can appear or persist in adulthood due to hormonal changes, external factors, or substance use, and requires appropriate treatment.

Pregnancy can cause skin changes and conditions that need correct diagnosis and treatment for the health of the mother and baby.