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Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

The document recommends using both clinical evaluation and various measurement methods to assess skin greasiness, considering factors like temperature and hormones.

Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.

New treatments for male hypogonadism are effective and should be personalized.

The human type II 5α-reductase gene has a specific structure important for understanding certain medical conditions.

Lifestyle changes improve metabolism and fertility in overweight PCOS patients; anti-obesity drugs show potential but need more research.

Many young women who donate blood have hormonal disorders like excess male hormones and PCOS.

Trichoscopy is a quick, cost-effective tool for diagnosing different hair loss conditions.

Hirsutism is a strong sign of high male hormones and metabolic problems in women with PCOS, but acne and hair loss are not.

Some psychiatric medications can cause hair loss, but it usually grows back after adjusting the medication.

New genetic discoveries may lead to better treatments for alopecia areata.

Baldness caused by male hormones in female-to-male transsexuals doesn't increase the risk of heart disease.

Nearly all elderly nursing home residents had a skin disease, with dry skin being the most common.

The document concludes that hair transplantation and gene therapy may be important for future hair loss treatment.

Cytokines and neuropeptides are key in controlling androgen levels, affecting skin and hair conditions.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Testosterone therapy can help improve sexual desire and function in postmenopausal women but may cause side effects and is not FDA-approved for this use.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

Adult female acne requires a comprehensive treatment approach, including medical options and lifestyle changes, with attention to psychological well-being.

Women with PCOS are more likely to have insulin resistance and obesity, especially those with the most severe type I PCOS.

The conclusion is that oral contraceptives and antiandrogens can treat hirsutism and acne in women with cutaneous hyperandrogenism, but more research is needed for effective treatments, especially for hair loss.

Early and personalized treatment for hair loss in young people is crucial to prevent permanent damage and should include psychological support.

The document concluded that more research is needed to find the best treatment for Frontal fibrosing alopecia.

Hair loss requires customized treatments based on its various causes and types.

LEF1 interacts with Vitamin D Receptor, affecting hair follicle regeneration and this could be linked to hair loss conditions.