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Poplar seed hairs grow from the placenta at the ovary base, with endoreduplication playing a key role in their development, and share similar cellulose synthesis processes with cotton fibers.

miR-29a-5p prevents the formation of early hair structures by targeting a gene important for hair growth and is regulated by a complex network involving lncRNA627.1.

EDA signaling is linked to skin disorders, various cancers, and liver disease.

Dermatologists are crucial for managing skin side effects in metastatic melanoma patients using vemurafenib and ipilimumab.

Stem cells from umbilical cords can help regrow hair in mice with hair loss.

Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.

Eicosanoids are crucial for skin health, and targeting their pathways may help treat skin conditions.

Patient-derived melanocytes can potentially treat vitiligo by restoring skin pigmentation.

Extracellular vesicles show promise for treating psoriasis by reducing inflammation and skin lesions.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

Hair thinning causes stem cell loss through a process involving Piezo1, calcium, and TNF-α.

P-cadherin is crucial for hair follicle pigmentation but not skin pigmentation.

Endocannabinoids help control mast cell activity in human skin.

Understanding where cancer cells come from helps create better prevention and treatment methods.

Celsr1 is crucial for skin cell alignment, while Celsr2 has little effect on this process.

Enhancers and super-enhancers are key in controlling specific gene activity and can play a role in cancer development.

Changing light exposure can affect hair growth timing in goats, possibly due to a key gene, CSDC2.

CPK1 helps root hair growth in Arabidopsis by activating channels for calcium signaling.

BMP signaling is essential for the development of touch domes.

Mesenchymal Stem/Stromal Cells (MSCs) help in wound healing and tissue regeneration, but can also contribute to tumor growth. They show promise in treating chronic wounds and certain burns, but their full healing mechanisms and potential challenges need further exploration.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.

EDA and EDAR are important for hair follicle development in cashmere goats and affect other related genes.

Active oxygen species might be involved in skin tumor growth, but their exact role is unclear.

Non-coding RNAs help control hair growth in cashmere goats.

Macrophages are essential for successful skin growth in reconstructive surgery.

Cathepsin L is essential for normal hair growth and development.

Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.

The document explains how to create detailed biological pathways using genomic data and tools, with examples of hair and breast development.