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Tissue environment greatly affects the unique epigenetic makeup of regulatory T cells, which could impact autoimmune disease treatment.

Enhancing cannabinoid signaling may help treat skin inflammation.

Overactivating Hedgehog signaling makes hair follicle cells in mice grow hair faster and create more follicles.

Fibroblasts are important in healing diabetic wounds, but high sugar levels can harm their function and slow down the healing process.

People with reproductive, thyroid disorders, and type 2 diabetes can experience voice changes, but more research is needed to understand this better.

Hormones and neuroendocrine factors control hair growth and color, and more research could lead to new hair treatment options.

PCOS is diagnosed when at least two of these three features are present: polycystic ovaries, irregular ovulation, and high androgen levels.

About 2.2% of women with symptoms of high male hormones have a mild form of congenital adrenal hyperplasia, and measuring a specific hormone level can accurately diagnose it.

The document concludes that hirsutism is the main sign for diagnosing hyperandrogenism, which requires a detailed patient history and physical exam.

Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.

The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.

Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.

High afamin levels are linked to metabolic syndrome and may predict its development in women with insulin resistance.

Women with androgen excess, especially those with PCOS, have a much higher risk of heart disease and stroke.

Using neurohormones to control keratin can lead to new skin disease treatments.

Insulin resistance is linked to high male hormone levels in women, often seen in those with PCOS.

ARL15 is important for fat cell development and the release of the hormone adiponectin.

Most cases of excessive hair growth in women are caused by polycystic ovarian syndrome and are linked to higher free testosterone levels.

Melanoblasts migrate to the skin using various pathways, and understanding this process could help with skin disease research.

Low-dose finasteride effectively reduces hirsutism without serious side-effects.

Blood tests are needed to confirm high male hormone levels in women with PCOS, as physical signs alone are not reliable.

Knuckle Acanthosis Nigricans is common in Latin American youth and may indicate early insulin resistance, especially in those with normal weight.

Antiandrogens are the main treatment for hirsutism, with individualized care and safe, affordable options needed.

A young woman's symptoms suggested PCOS, but tests and surgery confirmed and treated a rare ovarian tumor, resolving her condition.

Women with PCOS often have sexual problems, and treating these issues early can improve satisfaction and reduce healthcare costs.

Wnt5a may slow down hair growth in mice.

The document concludes that hirsutism can be managed with various treatments tailored to the individual, potentially improving quality of life.

Most children with a common hemochromatosis genotype had elevated iron levels but no severe symptoms.

Diagnosing simple-virilizing congenital adrenal hyperplasia can be difficult and requires thorough testing and expert advice.

T cells and bacteria in the gut and skin help maintain health and protect against disease.