research Therapeutic Effect of Combined Platelet-Rich Plasma Strategies on Morphea
Combining platelet-rich plasma injections and gel may effectively treat morphea, improving skin elasticity and reducing pain.
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research LGR5 Is a Conserved Marker of Hair Follicle Stem Cells in Multiple Species and Is Present Early and Throughout Follicle Morphogenesis
LGR5 is a common marker of hair follicle stem cells in different animals and is important for hair growth and regeneration.
research HaCaT-Conditioned Medium Supplemented with Small Molecule Inhibitors SB431542 and CHIR99021 and Growth Factor PDGF-AA Prevents the Dedifferentiation of Dermal Papilla Cells In Vitro
A mix of specific inhibitors and a growth factor helps keep hair growth cells from losing their properties in the lab.
research Selection Signatures for Fiber Production in Commercial Species: A Review
Genomic research can help improve the quality and production of natural fibers in animals.
research Molecular and Spatial Design of Early Skin Development
The research reveals how early embryonic mouse skin develops from simple to complex structures, identifying various cell types and their roles in this process.
research Autophagy Dysfunction: The Kernel of Hair Loss?
Manipulating cell cleanup processes could help treat hair loss.
research Translational Research in the Generation of Therapeutic Medicine for Wound Healing: A Review
New therapies show promise for wound healing, but more research is needed for safe, affordable options.
research Assessment of Vitamin D Level in Patients with Alopecia Areata
Low vitamin D levels are common in people with Alopecia Areata.
research Hair Follicle Reconstruction and Stem Cells
Stem cells could improve hair growth and new treatments for baldness are being researched.
research Hair Follicle Stem Cell Progeny Heal Blisters While Pausing Skin Development
When skin blisters, healing the wound is more important than growing hair, and certain stem cells mainly fix the blisters without helping hair growth.
research Extracellular Vesicles from Activated Dermal Fibroblasts Stimulate Hair Follicle Growth Through Dermal Papilla-Secreted Norrin
Special particles from skin cells can promote hair growth by activating a specific growth signal.
research Alopecia
The document concludes that alopecia has significant social and psychological effects, leading to a market for hair loss treatments.
research RE-ORGA, a Korean Herb Extract, Can Prevent Hair Loss Induced by Dihydrotestosterone in Human Dermal Papilla Cells
RE-ORGA, a Korean herb extract, may help prevent hair loss.
research Topical Sodium Valproate-Loaded Nanospanlastics Versus Conventional Topical Steroid Therapy in Alopecia Areata: A Randomized Controlled Study
Both treatments for alopecia areata showed similar modest effectiveness.
research Single-Cell Sequencing Reveals the Intermediate Cell State and Function of Dermal Papilla Cells in the Hair Follicle Cycle of Cashmere Goats
Researchers found four key stages of cell development that are important for hair growth and shedding in cashmere goats.
research Biology of Melanocytes in Mammals
Melanocytes are important for skin and hair color and protect the skin from UV damage.
research Impaired LEF1 Activation Accelerates iPSC-Derived Keratinocytes Differentiation in Hutchinson-Gilford Progeria Syndrome
Faulty LEF1 activation causes faster skin cell differentiation in premature aging syndrome.
research A Human Prenatal Skin Cell Atlas Reveals Immune Cell Regulation of Skin Morphogenesis
Immune cells are essential for early hair and skin development and healing.
research The Hair Follicle: Functions, Self-Renewal, and Alopecic Disorders
Dogs could be good models for studying human hair growth and hair loss.
research Hair Follicle Stem Cell Progeny Heal Blisters While Pausing Skin Development
Skin healing from blisters can delay hair growth as stem cells focus on repairing skin over developing hair.
research Tissue-Selective Regulation of Androgen-Responsive Genes
The same hormone can affect gene expression differently in various tissues, which could lead to new treatments for conditions like hair loss.
research Olfactory Receptor OR2AT4 Regulates Human Hair Growth
A certain smell receptor in hair follicles can affect hair growth when activated by a synthetic sandalwood scent.
research SIRT7 Activates Quiescent Hair Follicle Stem Cells to Ensure Hair Growth in Mice
SIRT7 protein is crucial for starting hair growth in mice.
research Emerging Role of Dermal White Adipose Tissue in Modulating Hair Follicle Development During Aging
Fat tissue under the skin affects hair growth and aging; reducing its inflammation may help treat hair loss.
research Metabolic Regulation of Stem Cells in Aging
Eating less can improve stem cell function and increase lifespan.
research Macrophages Promote Wound-Induced Hair Follicle Regeneration in a CX3CR1- and TGF-β1-Dependent Manner
Macrophages help hair growth after injury through CX3CR1 and TGF-β1.
research 3,4,5-Tri-O-Caffeoylquinic Acid Promoted Hair Pigmentation Through β-Catenin and Its Target Genes
A substance called TCQA could potentially darken hair by activating certain genes and increasing melanin.
research Historical and Current Adenosine Receptor Agonists in Preclinical and Clinical Development
The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.
research MTORC1 Activity Negatively Regulates Human Hair Follicle Growth and Pigmentation
High mTORC1 activity slows hair growth and causes it to lose color.
research Ectodysplasin Research: Where to Next?
Future research on ectodysplasin should explore its role in diseases, stem cells, and evolution, and continue developing treatments for genetic disorders like hypohidrotic ectodermal dysplasia.