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Methotrexate for rheumatoid arthritis often causes side effects like diarrhea, fatigue, and hair loss, especially at higher doses.

Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.

Biologic agents can be effective for rheumatic diseases but have risks like infections and require careful monitoring and patient information.

The document concludes that lifestyle changes and medical treatments can significantly reduce symptoms of Hidradenitis Suppurativa, a chronic skin condition.

PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.

Patients need better information about the risks of long-term steroid use.

Hair loss greatly affects quality of life, and dermatologists are crucial for proper diagnosis and treatment.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

Baricitinib helps treat several diseases, including COVID-19, but has side effects and needs careful monitoring.

Belimumab effectively controls SLE disease activity and reduces steroid use.

Non-biologic immunosuppressive drugs are crucial for treating autoimmune and chronic inflammatory skin diseases.

HS patients rarely see dermatologists, often get opiates, and need better care.

COVID-19 can cause skin issues like rashes and "COVID toes," and people with skin conditions should adjust their treatments if they get the virus.

Psoriasis treatments don't raise severe COVID-19 risk, except for acitretin.

Patients with chronic skin conditions on systemic treatments did not have worse COVID-19 outcomes and could resume their treatments after recovery.

Cell therapy shows promise for treating severe psoriasis but needs more research to confirm safety and effectiveness.

Basaloid follicular hamartoma's appearance can be similar to other skin conditions, and diagnosis should consider both the look and behavior of the tumor.

The debate focuses on the role of catagen and hair shedding mechanisms in telogen effluvium.

Both parties agree that cell death is important in the hair cycle, but they have different views on the role of the catagen phase and hair shedding.

Alopecia areata is a hair loss condition caused by immune factors and can be treated with JAK inhibitors.

Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

COVID-19 can cause skin issues like "COVID toes," rashes, hair loss, and hand eczema, and dermatologists are important for recognizing these signs.

Anifrolumab treatment improves quality of life and reduces disease activity and steroid use in SLE patients.

Dermoscopy helps diagnose unusual skin lesions like osteonevus of Nanta and can prevent misdiagnosis of serious conditions.

New treatments for non-small cell lung cancer are being tested, with some already in use, focusing on immune response and targeting cancer cells, but side effects vary.

The document summarizes important skin care topics for non-specialist doctors, including treatments for skin conditions and the management of skin diseases.

New treatments for hair loss are showing promise due to better understanding of genetics and the immune system.

More precise, personalized therapies are needed for autoimmune diseases.

Ultrasound shows 96% of young men with erectile dysfunction after using finasteride have abnormal penile tissue.