26 citations,
January 2007 in “Organogenesis” Bioengineering can potentially treat hair loss by regenerating hair follicles and cloning hair, but the process is complex and needs more research.
50 citations,
March 2001 in “Clinics in Dermatology” Genes and hormones cause hair loss, with four genes contributing equally.
January 2022 in “Figshare” Dexamethasone increases androgen receptor activity in scalp cells, which might explain stress-related hair loss.
June 2012 in “Nature digest” A substance called prostaglandin D2 is linked to stopping hair growth in men with common baldness.
3 citations,
May 2008 in “Hair transplant forum international” Common hair loss disorders may not need stem cell therapy, but could benefit from other treatments like hair cycle control and immune restoration therapy.
34 citations,
February 1999 in “Journal of Dermatological Science” Minoxidil boosts enzymes that help hair growth.
8 citations,
October 2008 in “Medical hypotheses” Baldness might be caused by scalp weight pressing on hair follicles.
December 2023 in “Scientific Reports” Scientists created cell lines from balding patients and found that cells from the front of the scalp are more affected by hormones that cause hair loss than those from the back.
49 citations,
August 2003 in “Journal of The American Academy of Dermatology” Higher IGF-1 levels in hair follicles link to better finasteride results for hair loss.
32 citations,
January 1990 in “Clinical Endocrinology” Women with female pattern hair loss have higher levels of certain androgens, suggesting increased androgen exposure to hair follicles.
8 citations,
September 2008 in “Medical Hypotheses” The paper suggests that hair loss might be caused by skull growth, not just DHT's effect on hair follicles, and calls for more research.
3 citations,
November 2021 in “Frontiers in Medicine” Advanced male pattern baldness affects the back of the scalp, reducing hair follicles.
8 citations,
January 2015 in “Scars, burns & healing” Hair transplantation effectively treats burn scar alopecia, improving self-esteem and confidence.
19 citations,
February 2008 in “Archives of Dermatological Research” Mast cells might contribute to hair loss by causing skin thickening.
January 2009 in “Egyptian Journal of Medical Human Genetics” The study suggests that a specific gene variation and higher gene activity are linked to increased baldness in Egyptian men.
8 citations,
June 2019 in “Scientific Reports” Increased PPARGC1α relates to hair thinning in common baldness.
58 citations,
September 2012 in “Dermatologic Clinics” Male pattern hair loss caused by follicular miniaturization; early diagnosis and treatment can reduce psychological burden.
1 citations,
April 2016 in “Journal of Investigative Dermatology” Blocking Prostaglandin D₂ may help treat hair loss.
93 citations,
February 2015 in “Journal of Investigative Dermatology” Oxidative stress affects hair loss in men with androgenetic alopecia.
162 citations,
August 2002 in “Survey of Ophthalmology” Latanoprost can make eyelashes longer, thicker, and darker.
112 citations,
October 2005 in “Mayo Clinic Proceedings” Minoxidil and finasteride can slow hair loss and stimulate regrowth, but won't restore all lost hair or reverse complete baldness.
41 citations,
March 1998 in “Archives of Dermatological Research” The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.
3 citations,
October 2019 in “Dermatologic Therapy” Hair loss in men is mainly caused by hormones and genes, and while current treatments can slow it down, they can't fully stop it.
6 citations,
January 2022 in “Journal of Investigative Dermatology” Male pattern baldness is linked to higher levels of a certain receptor in the scalp, which leads to the shrinking of blood vessels and hair loss. Early treatment targeting this receptor could be more effective.
1 citations,
October 2021 in “Clinical, Cosmetic and Investigational Dermatology” Vitamin B3 may help prevent hair loss and promote hair growth by protecting scalp cells from stress and reducing hair growth-blocking proteins.
May 2009 in “Hair transplant forum international” Androgens affect hair growth and shedding, with genetic and non-genetic factors influencing baldness.
Alopecia areata, a type of hair loss, may be passed through T cells and has genetic links, while treatments vary in effectiveness. Male pattern baldness can be treated with finasteride and is influenced by androgens in hair follicles.
2 citations,
January 2022 in “Skin Pharmacology and Physiology” Dexamethasone increases the activity of androgen receptors in human skin cells, which may link it to certain types of hair loss.
4 citations,
January 2018 in “Annals of dermatology/Annals of Dermatology” Hair transplantation successfully treated hair loss in a patient with Trichorhinophalangeal syndrome.
January 2024 in “Journal of Cosmetic Dermatology” Men's and women's pattern hair loss progress differently, with men showing more hair thinning and women having more widespread hair loss.