328 citations,
November 2020 in “Nature Materials” Hydrogel scaffolds can help wounds heal better and grow hair.
18 citations,
March 2022 in “Drug design, development and therapy” Platelet-rich plasma (PRP) may help with various hair loss types, but more research is needed to find the best use method.
10 citations,
September 2021 in “JAMA Dermatology” Different types of persistent hair loss after chemotherapy respond differently to treatments.
2 citations,
April 2023 in “BMC endocrine disorders” The link between physical signs of high male hormones and hormone levels in women with PCOS changes with age.
January 2020 in “Journal of Cosmetics, Dermatological Sciences and Applications” DEEPLY ROOTED® supplement seems to effectively improve hair growth and quality in women with no side effects.
14 citations,
January 2016 in “Experimental Dermatology” Hair regrowth doesn't convert thin hairs to thick hairs, but increases overall hair density.
6 citations,
February 2016 in “American Journal of Dermatopathology” The boy with woolly hair nevus had thinner hair and abnormal hair follicles, which improved with treatment but worsened when treatment stopped.
18 citations,
August 2019 in “Drug Development and Industrial Pharmacy” Quercetin-loaded nanoparticles can penetrate skin, minimize hair loss, and promote hair regrowth, showing slightly better results than a marketed product.
316 citations,
June 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” Microspheres about 1.5 micrometers in size can best penetrate hair follicles, potentially reaching important stem cells.
19 citations,
March 1996 in “British Journal of Dermatology” Balding hair follicle cells are smaller, grow less well, and need more effort to culture than non-balding cells.
88 citations,
May 2005 in “Journal of Dermatological Science” Versican, a protein, is less present in thinning hair follicles and this decrease might contribute to common hair loss in men.
10 citations,
May 2012 in “PloS one” Low ERCC3 gene activity is linked to non-pigmented hair growth.
39 citations,
August 2018 in “Scientific reports” Claudin-1 is important for the barrier function and growth of hair.
70 citations,
April 2017 in “Lasers in surgery and medicine” Blue light promotes hair growth by interacting with specific receptors in hair follicles.
April 2017 in “Journal of Investigative Dermatology” Dermal Wnt/β-catenin signaling is important for the proper size and development of hair follicles.
1 citations,
May 2017 in “InTech eBooks” Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.
April 2017 in “Journal of Investigative Dermatology” The protein CTCF is essential for skin development, maintaining hair follicles, and preventing inflammation.
9 citations,
November 2009 in “Journal of the European Academy of Dermatology and Venereology” Cutting scalp biopsies in consecutive slices improves diagnosis of hair loss conditions.
7 citations,
December 2016 in “British Journal of Dermatology” The report suggests that hair loss in Cronkhite-Canada syndrome may be caused by alopecia areata incognita, as shown by a patient's improvement with treatment.
February 2024 in “International Journal of Molecular Sciences” Hair loss in Androgenetic Alopecia is caused by genetics, aging, and lifestyle, leading to hair follicle shrinkage and related health risks.
75 citations,
May 1986 in “Clinics in endocrinology and metabolism” Male hormones are important for hair and oil gland development and can cause conditions like excessive hair growth and acne.
53 citations,
October 2012 in “The FASEB Journal” Bimatoprost, a glaucoma medication, may also help treat hair loss.
14 citations,
July 2016 in “Environmental Toxicology and Pharmacology” Cedrol may prevent hair loss caused by chemotherapy better than minoxidil.
January 2023 in “Archives of Disease in Childhood Education & Practice” Hirsutism in teens is often due to polycystic ovarian syndrome and needs careful assessment and support.
28 citations,
September 1998 in “Medical Clinics of North America” Most hair loss can be diagnosed with patient history and physical exam, and a few common types make up most cases.
8 citations,
January 2020 in “Skin Pharmacology and Physiology” Caffeine improves hair growth, thickness, and reduces shedding.
29 citations,
June 2013 in “Journal of the Saudi Society of Dermatology & Dermatologic Surgery” Alopecia areata is an autoimmune hair loss condition treated with corticosteroids, and histologic confirmation is the best diagnosis method.
April 2017 in “Journal of Investigative Dermatology” Certain microRNAs may protect against hair loss in alopecia areata and could be potential treatment targets.
130 citations,
August 2015 in “Experimental Dermatology” Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.
5 citations,
March 2015 in “Clinical and Experimental Dermatology” Chemotherapy caused a woman's permanent hair loss and early menopause.