This study explored new molecular structures as potential COVID-19 treatments, identifying a compound called Hit15 that inhibited viral infection in lab settings and reduced inflammation markers in human neutrophils, suggesting further development is warranted.
This study found that culturing fibroblasts on stiffer substrates mimicking fibrotic wounds led to an aligned EDA fibronectin matrix with thinner fibers and decreased YAP activity, suggesting disrupted signaling that might be restored to promote regenerative wound repair.
April 2024 in “Frontiers in pharmacology” This review of Cynoglossum amabile, a traditional Chinese and ethnomedicine, provides insights into its uses, chemical components, biological activities, and toxicity. Highlighting its market potential, the study underscores the importance of indigenous knowledge in drug development despite noted hepatotoxic risk linked to its pyrrolizidine alkaloids.
March 2024 in “Journal of Pharmaceutical and Sciences” This study investigated the phytochemical composition and antibacterial and antioxidant activities of Zaleya pentandra extracts, finding high total polyphenol and flavonoid content and significant antibacterial effects, particularly in acetone extract, which may be suitable for developing antibacterial agents.
February 2024 in “Trends in Sciences” This study examined the stability of two 5α-reductase inhibitors in Tectona grandis extracts, finding that they are more stable in acidic environments and degrade rapidly under heat and light unless protected, suggesting the need for careful storage when developing anti-hair loss medications.
January 2024 in “Diabetes & metabolism journal” This review explored how the circadian system might influence diabetes development and management, highlighting mismatches like disrupted sleep-wake cycles and gene mutations that could worsen diabetes, and suggests targeting these for future diabetes prevention and treatment strategies.
January 2024 in “Biological & clinical sciences research journal” This review of 355 articles found that apigenin, a compound found in many plants and vegetables, is mainly researched for its anti-inflammatory, neuroprotective, and anti-cancer properties, with enhanced efficacy when combined with allopathic drugs.
January 2024 in “Wiadomości Lekarskie” This source reports that clinical trials using advanced Deep Brain Stimulation systems, augmented with AI to integrate kinematic data, eye tracking, and cognitive assessments, show promise in improving diagnostic accuracy and monitoring symptoms for patients with Parkinson's disease.
January 2024 in “Wiadomości Lekarskie” In this retrospective study conducted at Grodno Regional Children's Hospital, researchers found that children in western Belarus showed more severe COVID-19 symptoms in 2021 compared to 2020, with urban children primarily affected, and family contact emerging as the most common source of infection.
January 2024 in “Wiadomości Lekarskie” This study reported the development of fluorescent markers using wide band gap metal oxides with rare earth ions for early tumor detection and treatment. Testing in animals showed high efficiency and selectivity, with potential applications in contrast-enhanced MRI, targeted drug delivery, and photodynamic cancer therapy.
January 2024 in “Wiadomości Lekarskie” This study developed an AI-driven method for classifying cells in Follicular Lymphoma cases, achieving a 63% F1-score, precision, and recall in distinguishing centroblasts from other cell types using whole slide images at x20 resolution.
January 2024 in “Wiadomości Lekarskie” This article reviews the potential applications of Point of Care procedures in radiology, discussing their ability to enhance the speed of diagnosis and treatment but does not report new results.
This study found that elastin-like recombinamer (ELR) wound dressings promote tissue regeneration and stability without rejection in ex vivo and in vivo models, indicating potential for hard-to-heal wound treatment.
January 2024 in “Wiadomości Lekarskie” This study found that using a combined LH and FSH stimulation protocol significantly increased clinical pregnancy rates in women with low ovarian reserve compared to the standard protocol.
January 2024 in “Wiadomości Lekarskie” This study highlights the growing role of artificial intelligence in vascular surgery, where AI improves diagnostic accuracy, surgical planning, and patient monitoring, ultimately enhancing clinical outcomes, shortening recovery times, and reducing healthcare costs.
January 2024 in “Wiadomości Lekarskie” AI and advanced technologies are improving medical diagnostics and treatments.
January 2024 in “Wiadomości Lekarskie” In this study, researchers analyzed spermogram data from men with diagnosed infertility in Ukraine, aiming to identify the most common sperm disorders, and they found that the study primarily involved men with primary infertility, compared to a control group of healthy men with confirmed fertility.
January 2024 in “Wiadomości Lekarskie” This review discusses the potential of augmented reality to advance vascular and endovascular surgery by improving 3D anatomical understanding and reducing patient risk, but notes that further research is needed to overcome current technological limitations.
January 2024 in “Wiadomości Lekarskie” This abstract outlines a lecture discussing the rise of influencers alongside the internet, highlighting their impact on user behavior in social media by sharing personal experiences and engaging in political and medical discourse.
January 2024 in “Wiadomości Lekarskie” In this study, researchers examined a patient with ZMYM2::FGFR1 fusion-positive leukemia, finding that Pemigatinib showed efficacy, while Ponatinib resistance was linked to a specific FGFR1 mutation. Other FGFR inhibitors demonstrated high effectiveness in ex vivo assays.
January 2024 in “Wiadomości Lekarskie” This study discusses promising research advancements that may improve treatment outcomes for glioblastomas, highlighting stereotactic radiosurgery, FET-PET imaging, and alternating electric field therapy as potential strategies. The abstract emphasizes the need for ongoing and future trials to determine their effectiveness in clinical practice.
January 2024 in “Wiadomości Lekarskie” This presentation discusses the importance of fluid therapy in critical care, reviewing current data, guidelines, and emerging technologies to help clinicians make informed decisions about fluid type and volume for treating critically ill patients. Results are not reported in this abstract.
January 2024 in “Wiadomości Lekarskie” This review highlights that AI-based echocardiography in cardiology can enhance diagnostic precision, automation, and therapeutic strategy development, but also presents challenges like diagnostic errors and high costs, indicating a cautious yet promising progression in its adoption.
January 2024 in “Wiadomości Lekarskie” This study discusses the need for better organization and specialized services in Alzheimer's prevention, focusing on modifiable factors like hearing impairment, vascular risk, and lifestyle habits, and highlights challenges and opportunities from the two-year experience of Brain Health services at Karolinska Institutet in Sweden.
January 2024 in “Wiadomości Lekarskie” This study reports how the Polish-American Medical Society (ZLP Chicago) played a proactive role during the COVID-19 pandemic in the Chicago area, leading efforts in public education, support for administrative measures, and dissemination of health guidelines to the Polish community.
January 2024 in “Wiadomości Lekarskie” This source outlines the potential benefits and challenges of integrating advanced care at home programs with hospital medicine, highlighting their implications for healthcare systems and the necessary technological support. Results are not detailed in the abstract.
January 2024 in “Wiadomości Lekarskie” This review addresses the historical and cultural perceptions of epilepsy and stresses the importance of understanding its diagnosis and management to lessen its psychological and social impacts, especially given the stigma often associated with this condition.
January 2024 in “Wiadomości Lekarskie” In this study, the integration of artificial intelligence in medicine was discussed, highlighting its potential to enhance diagnostic processes, optimize therapies, and provide advanced patient monitoring despite challenges like data inconsistency and limited model transparency.
January 2024 in “Wiadomości Lekarskie” In this case-control study, researchers investigated the association between SIRT1 gene polymorphisms and colorectal cancer risk, finding no statistically significant differences in polymorphism frequencies between patients and controls, but noted trends that warrant further study in larger populations.
January 2024 in “Wiadomości Lekarskie” This study reported that interdisciplinary treatment, combining surgical and rehabilitation methods, led to satisfactory outcomes for patients with extensive facial skull injuries. The authors emphasized the importance of teamwork between surgeons and physiotherapists to minimize complications and enhance recovery, restoring function, aesthetics, and physical fitness.