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New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

Neurosteroids show promise for treating epilepsy and more research is needed.

Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.

The document concludes that more research is needed to understand how to treat muscle pain with drugs.

Human enzymes can detoxify harmful substances but might also increase their cancer risk.

Progesterone boosts alcohol's effect on brain, finasteride counters it.

*Acorus calamus* has many medicinal benefits but needs more safety research.

PFS and PSSD are similar conditions with persistent sexual dysfunction after stopping medication.

Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

Behavioral dermatology treats skin problems by considering both emotional and physical factors.

Blocking CRF-R1 can reduce alcohol intake in stressed mice.

The current system can't fully test all combination treatments, so alternative methods and regulatory flexibility are needed.

The protein SLC1A3 is important for activating skin stem cells and is necessary for normal hair and skin growth in mice.

Some hormone-related drugs may protect brain cells in Parkinson's disease differently in men and women.

Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.

Finasteride reduces alcohol withdrawal severity in male mice but increases it in female mice.

Systemic Lupus Erythematosus has varied symptoms and is hard to diagnose, affecting many body parts and requiring careful clinical judgment.

Finasteride reduces new brain cells in male mice, possibly causing depression.

Ziziphus jujuba Mills may have health benefits, but more research is needed to confirm its safety and effectiveness.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Parkinson's disease is linked to skin disorders and skin cells help in studying the disease.

The enzyme 5α-reductase is key in causing psychotic-like effects from sleep deprivation.

Safflower has been used in traditional medicine for centuries and shows promise in treating heart, brain, and inflammatory conditions, but more research is needed to ensure its safety.