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Stress may trigger hair loss by affecting immune protection in hair follicles.

Quercetin effectively treated and prevented hair loss in mice.

Eating a Mediterranean diet and taking certain supplements may improve symptoms of PCOS.

The nervous system helps control stem cell behavior and immune responses, affecting tissue repair and maintenance.

Obesity leads to physical, metabolic, reproductive issues, higher healthcare costs, and mental health problems.

Melanocytes are important for normal body functions and have potential uses in regenerative medicine and disease treatment.

New treatments and strategies are needed for Alopecia Areata, focusing on immune response and better trial designs.

Mesenchymal Stem/Stromal Cells (MSCs) help in wound healing and tissue regeneration, but can also contribute to tumor growth. They show promise in treating chronic wounds and certain burns, but their full healing mechanisms and potential challenges need further exploration.

Men are more likely to have severe respiratory viral infections like COVID-19 due to hormonal and genetic differences, while women generally have stronger immune responses.

Alopecia areata involves both innate and adaptive immunity, with specific genes linked to the disease.

Lysophospholipids like LPA and S1P are important for hair growth, immune responses, and vascular development, and could be targeted for treating diseases.

Vitamin D is important for bones, hair, blood pressure, and breast development.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Females have higher estrogen receptor levels in hair than males, and these levels decrease in white hair compared to black hair.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Epidermal keratinocytes start wound healing and inflammation after schistosome infection.

Olive leaf compound oleuropein helps grow hair in mice.

Three specific proteins can turn adult skin cells into hair-growing cells, suggesting a new hair loss treatment.

No cure exists for alopecia areata, and treatments are personalized.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Topical JAK inhibitors may help treat alopecia universalis by promoting hair regrowth.

NK cells play a role in skin diseases like eczema and psoriasis.

Canine pemphigus foliaceus involves significant immune activity and shares similarities with human pemphigus.

JAK inhibitors are effective in treating various immune-related diseases, not just rheumatoid arthritis.

Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.

Type I interferons play a key role in the development of various skin diseases.

People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.