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This study indicates that activating K+ channels in dermal papilla cells alone may not promote hair growth, despite some openers being effective on certain channels.

This article reviews the use of hydralazine, minoxidil, and sodium nitroprusside in managing hypertension and hypertensive crises, noting specific indications, adverse effects, and the adjunctive therapies needed to mitigate side effects.

This article discusses the use of direct vasodilators and sympatholytic agents in hypertension management, highlighting their utility in specific cases like refractory hypertension and heart failure, but reports no new clinical results.

Nitrendipine and nifedipine effectively block muscle contractions, while papaverine relaxes them and minoxidil needs high amounts to work.

New drugs like clonidine and prazosin show promise for treating high blood pressure despite some side effects.

Minoxidil lowers blood pressure more effectively but has more side effects, so try hydralazine first.

This article discusses the potential therapeutic applications of topical nitroglycerin formulations in various medical conditions, but it reports no new clinical results.

These drugs raise prostaglandin-like material in dog blood, possibly causing blood vessel widening.

In this study, minoxidil-induced vasodilation in rat aorta was found to be mediated by ATP-sensitive potassium channels and nitric oxide pathways, but was not significantly altered by lipid emulsion pretreatment.

In this study, minoxidil sulfate was found to relax norepinephrine-induced contractions in rabbit mesenteric arteries, possibly by acting as a K+ channel agonist, but it did not relax K+-induced contractions.

This study found that hydralazine and minoxidil, two direct vasodilators, may worsen abdominal aortic aneurysm progression by increasing aortic degeneration and inflammation.

In this study, oral minoxidil combined with other medications improved blood pressure control in patients with severe hypertension but often had to be discontinued due to side effects.

Minoxidil effectively lowers blood pressure in patients with resistant hypertension.

Diazoxide, minoxidil sulphate, and cromakalim relax rat blood vessels by opening K+ channels, with some differences in their actions.

This study found that topically applied minoxidil was more effective than nitroglycerin and placebo in enhancing penile diameter, rigidity, and arterial flow, with the most pronounced effects in patients with neurogenic impotence.

This review discusses nitric oxide's physiological roles and the development of strategies for delivering it exogenously, without presenting new clinical results.

This article provides contact information for Professor A. Brew Atkinson and reports no new research findings; it is not a study abstract.

The authors concluded that diazoxide reduces undesirable side effects compared to minoxidil while increasing elastic fiber content and decreasing cell number in the aorta, suggesting potential suitability for treating vascular conditions with low arterial elastin and hypertension.

This review discusses the development and potential therapeutic effects of nitroxide small molecule agents for age-related macular degeneration and cardiovascular disease, but reports no new clinical results.

This study found that combining 4 mg doxazosin with 0.2 mg tamsulosin improved urinary symptoms with fewer vasodilatory side effects compared to a higher dose of doxazosin in hypertensive males with LUTS.

This study found that minoxidil increased plasma renin activity in patients with hypertension through both an adrenergic mechanism related to heart rate changes and a secondary mechanism unrelated to propranolol.

This study found that supraphysiological doses of testosterone alter endothelial relaxation pathways in hypertensive rats, with varied contributions from nitric oxide, prostanoids, and endothelium-derived hyperpolarizing factors, influenced by estrogen and dihydrotestosterone levels.

This article reviews guidelines and medications for treating benign prostatic hyperplasia but presents no new clinical results.

New treatments improved blood pressure control in patients with resistant hypertension.

This article reviews recent discoveries about the role of the nitroxide free radical NO in vascular physiology and suggests potential implications for minoxidil's vasodilatory action, but reports no new clinical findings.

This chapter reviews adverse effects of anti-anginal and beta-blocker drugs, stating that starting a beta-blocker may temporarily affect driving ability, but it reports no new clinical findings.

This study investigated the effects of 5-alpha-reductase inhibitors on penile histomorphometry in both normotensive and hypertensive rats, reporting no significant changes between treated and untreated groups.

This article discusses the challenges in hypertension management, emphasizing the need to reconsider the use of minoxidil and address excess dietary sodium and arteriolar hypertrophy, but reports no new clinical results.

Minoxidil effectively controls blood pressure in severe cases, but may cause fluid retention and edema.

This review identified two promising therapeutic targets for drug repurposing to treat refractory angina in patients with angina pectoris without obstructive coronary artery disease: endothelin-1 receptor blockers and soluble guanylate cyclase stimulators.